Zobrazeno 1 - 10
of 529
pro vyhledávání: '"Genetically engineered mouse models"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/a9a8996edca849559e3286979818e7ad
Autor:
Daowei Yang, Xinlei Sun, Rohan Moniruzzaman, Hua Wang, Citu Citu, Zhongming Zhao, Ignacio I. Wistuba, Huamin Wang, Anirban Maitra, Yang Chen
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101711- (2024)
Summary: Pancreatic cancer is associated with an oncogenic KRAS mutation in approximately 90% of cases. However, a non-negligible proportion of pancreatic cancer cases harbor wild-type KRAS (KRAS-WT). This study establishes genetically engineered mou
Externí odkaz:
https://doaj.org/article/86f14644049346438d351b6697eb089c
Autor:
Poppy Anjelisa Zaitun Hasibuan, Yogi Simanjuntak, Evamarie Hey-Hawkins, Muhammad Fauzan Lubis, Ade Sri Rohani, Moon Nyeo Park, Bonglee Kim, Rony Abdi Syahputra
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116827- (2024)
Colorectal cancer (CRC) is a major cause of cancer-related deaths worldwide, underscoring the importance of understanding the diverse molecular and genetic underpinnings of CRC to improve its diagnosis, prognosis, and treatment. This review delves in
Externí odkaz:
https://doaj.org/article/076b288dbbd24ca1a0bc4c35369f87e2
Autor:
Tang Y, Gutmann DH
Publikováno v:
Cancer Management and Research, Vol Volume 15, Pp 667-681 (2023)
Yunshuo Tang,1,2 David H Gutmann2 1Department of Ophthalmology, Washington University School of Medicine, St. Louis, MO, USA; 2Department of Neurology, Washington University School of Medicine, St. Louis, MO, USACorrespondence: David H Gutmann, Depar
Externí odkaz:
https://doaj.org/article/f830c922ea644b1cba265fb0eed7a274
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5704-5718 (2023)
Immunotherapy is a promising therapeutic domain for the treatment of gliomas. However, clinical trials of various immunotherapeutic modalities have not yielded significant improvements in patient survival. Preclinical models for glioma research shoul
Externí odkaz:
https://doaj.org/article/11a41bd6dc994db281d5568fe155436b
Autor:
Mary Katherine Montgomery, Chong Duan, Lisa Manzuk, Stephanie Chang, Aiyana Cubias, Sonja Brun, Anand Giddabasappa, Ziyue Karen Jiang
Publikováno v:
Translational Oncology, Vol 40, Iss , Pp 101833- (2024)
Lung cancer remains a leading cause of cancer-related death, but scientists have made great strides in developing new treatments recently, partly owing to the use of genetically engineered mouse models (GEMMs). GEMM tumors represent a translational m
Externí odkaz:
https://doaj.org/article/1f6dec55d9d74c09a1a45c10f6dcee86
Autor:
Tianyu Qin, Junpeng Fan, Funian Lu, Li Zhang, Chen Liu, Qiyue Xiong, Yang Zhao, Gang Chen, Chaoyang Sun
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-27 (2022)
Abstract Ovarian cancer (OC) is a heterogeneous malignancy with various etiology, histopathology, and biological feature. Despite accumulating understanding of OC in the post-genomic era, the preclinical knowledge still undergoes limited translation
Externí odkaz:
https://doaj.org/article/b4267ac11f184ed3952d09ff07905ecd
Autor:
Harikrishna Rallapalli, N. Sumru Bayin, Hannah Goldman, Dragan Maric, Brian J. Nieman, Alan P. Koretsky, Alexandra L. Joyner, Daniel H. Turnbull
Publikováno v:
NeuroImage, Vol 276, Iss , Pp 120198- (2023)
Magnetic Resonance Imaging (MRI) resolution continues to improve, making it important to understand the cellular basis for different MRI contrast mechanisms. Manganese-enhanced MRI (MEMRI) produces layer-specific contrast throughout the brain enablin
Externí odkaz:
https://doaj.org/article/f5291e0394464c1ea3b1b8d620ae031f
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Akademický článek
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