Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Genetically encoded calcium indicator"'
Autor:
Oksana M. Subach, Anna V. Vlaskina, Yulia K. Agapova, Alena Y. Nikolaeva, Anna M. Varizhuk, Oleg V. Podgorny, Kiryl D. Piatkevich, Maxim V. Patrushev, Konstantin M. Boyko, Fedor V. Subach
Publikováno v:
FEBS Open Bio, Vol 13, Iss 11, Pp 2047-2060 (2023)
Genetically encoded calcium indicators based on truncated troponin C are attractive probes for calcium imaging due to their relatively small molecular size and twofold reduced calcium ion buffering. However, the best‐suited members of this family,
Externí odkaz:
https://doaj.org/article/1f1660325fa647b5af79a6e6567d9c71
Autor:
Johannes Brockhaus, Iris Kahl, Mohiuddin Ahmad, Daniele Repetto, Carsten Reissner, Markus Missler
Publikováno v:
Cells, Vol 13, Iss 11, p 981 (2024)
Presynaptic Ca2+ influx through voltage-gated Ca2+ channels (VGCCs) is a key signal for synaptic vesicle release. Synaptic neurexins can partially determine the strength of transmission by regulating VGCCs. However, it is unknown whether neurexins mo
Externí odkaz:
https://doaj.org/article/aa43ca8fab874f8fa14b7d6695f9303a
Autor:
Katie M. Toperzer, Savannah J. Brennan, David J. Carroll, Eric A. Guisbert, Karen S. Kim Guisbert
Publikováno v:
Biology Open, Vol 12, Iss 9 (2023)
Externí odkaz:
https://doaj.org/article/89e3cc6291c345ed95a27741913c61e4
Akademický článek
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Publikováno v:
IEEE Access, Vol 9, Pp 118610-118623 (2021)
Monitoring the electrical neural signals is an important method for understanding the neuronal mechanism. In particular, in order to perform a cell-type-specific study, it is necessary to observe the concentration of calcium ions using fluorescent in
Externí odkaz:
https://doaj.org/article/440f6d7922a74e31aa1a02d25505ae1c
Autor:
Yohei Okubo
Publikováno v:
Journal of Pharmacological Sciences, Vol 144, Iss 2, Pp 83-88 (2020)
Astrocytes generate robust intracellular Ca2+ signals that are assumed to be key regulators of astrocytic function. Among various Ca2+ mobilization mechanisms, Ca2+ release from the endoplasmic reticulum (ER) via the inositol 1,4,5-trisphosphate rece
Externí odkaz:
https://doaj.org/article/c1f606f66a704b29b5c53d9a7dee7a51
Akademický článek
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Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10004 (2022)
Ca2+ is a ubiquitous second messenger, which allows eukaryotic cells to respond to external stimuli. The use of genetically encoded Ca2+ indicators allows real-time monitoring of cytosolic Ca2+ levels to study such responses. Here we explored the pos
Externí odkaz:
https://doaj.org/article/d05c4f1b60c14b019b0cfa3f0ae97324
Autor:
Christian Lohr, Antonia Beiersdorfer, Timo Fischer, Daniela Hirnet, Natalie Rotermund, Jessica Sauer, Kristina Schulz, Christine E. Gee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Ca2+ imaging is the most frequently used technique to study glial cell physiology. While chemical Ca2+ indicators served to visualize and measure changes in glial cell cytosolic Ca2+ concentration for several decades, genetically encoded Ca2+ indicat
Externí odkaz:
https://doaj.org/article/68c930d6ca174b7388de6584b00af867
Autor:
Lawrence Huang, Peter Ledochowitsch, Ulf Knoblich, Jérôme Lecoq, Gabe J Murphy, R Clay Reid, Saskia EJ de Vries, Christof Koch, Hongkui Zeng, Michael A Buice, Jack Waters, Lu Li
Publikováno v:
eLife, Vol 10 (2021)
Fluorescent calcium indicators are often used to investigate neural dynamics, but the relationship between fluorescence and action potentials (APs) remains unclear. Most APs can be detected when the soma almost fills the microscope’s field of view,
Externí odkaz:
https://doaj.org/article/82e769b44ca8434cb6517c2168640eea