Zobrazeno 1 - 10
of 516
pro vyhledávání: '"Genetic profiling"'
Autor:
Ji Hyun Kim, Jun-Young Shin, Seog-Yun Park, Sang-Soo Seo, Sokbom Kang, Chong Woo Yoo, Sang-Yoon Park, Myong Cheol Lim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract The somatic BRCA1 or BRCA2 Pathogenic Variant (PV)/Likely PV (LPV) from Next Generation Sequencing (NGS) is the most important biomarker for PARP inhibitor use and maintenance-targeted therapies. A discrepancy in the detection rates of BRCA1
Externí odkaz:
https://doaj.org/article/2bbce2b4127d4484afb5d95f69156782
Autor:
Rabab Fatima
Publikováno v:
EXCLI Journal : Experimental and Clinical Sciences, Vol 23, Pp 1229-1231 (2024)
Externí odkaz:
https://doaj.org/article/22f67a388c28496598d101a491e2c4c6
Autor:
Dong-Dong Jia, Tao Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Immune checkpoint inhibitors (ICI) have emerged as a promising therapeutic option for melanoma, which demonstrating improved clinical outcomes in melanoma patients regardless of specific genetic mutations. However, the identification of reli
Externí odkaz:
https://doaj.org/article/40e8f08c699c4ec8a9d35bf260231b81
Autor:
Amit Kumar Malviya, Puneet Khanna
Publikováno v:
National Board of Examinations Journal of Medical Sciences, Vol Volume 2, Iss Special Issue, Pp S22-S31 (2024)
Precision medicine in anesthesia represents a transformative approach aimed at optimizing anesthetic care by tailoring interventions to individual patient characteristics, particularly their genetic profile. Pharmacogenomics, a cornerstone of precisi
Externí odkaz:
https://doaj.org/article/38efeb9181354fbebc95da71b55fd09a
Autor:
Jing Di, Leonard N. Yenwongfai, Talal Arshad, Bin Huang, Jaclyn K. McDowell, Eric B. Durbin, Reinhold Munker, Sainan Wei
Publikováno v:
Biomedicines, Vol 12, Iss 11, p 2476 (2024)
Background: This retrospective cohort study investigates the prognostic significance of genetic mutations in Chronic Myelomonocytic Leukemia (CMML) and their association with treatment responses among patients treated at a single institution, juxtapo
Externí odkaz:
https://doaj.org/article/d344cdd755ee4ac1b5c6990100b50e33
Autor:
Boiko S.M.
Publikováno v:
Ukrainian Botanical Journal, Vol 80, Iss 3, Pp 283-291 (2023)
The expediency of using unique SSR DNA-markers of Schizophyllum commune for population genetic assays in various fungal species has been demonstrated. In Auricularia auricula-judae and Irpex lacteus, we observed formation of heterogeneous amplicons m
Externí odkaz:
https://doaj.org/article/03f297c689994cd994e96525b9873c70
Autor:
Stéphane Sauvagère, Amaury Pussiau, Sylvain Hubac, Audrey Gouello, Alexandre Poussard, Jean-Philippe Lavigne, Amel Larnane, Christian Siatka, Francis Hermitte
Publikováno v:
Forensic Sciences, Vol 3, Iss 2, Pp 316-329 (2023)
The IRCGN (Institut de Recherche Criminelle de la Gendarmerie Nationale) is a forensic science institute built by the French Gendarmerie which has the ability to exploit crime scene evidence. Any piece of evidence, anywhere in the world, in any envir
Externí odkaz:
https://doaj.org/article/87c595600c0440fa8e7470a097efe270
Autor:
Angela Liu, Paige Vicenzi, Ishna Sharma, Kaci Orr, Christa Teller, Micha Koentz, Heidi Trinkman, Kelly Vallance, Anish Ray
Publikováno v:
Hematology Reports, Vol 15, Iss 2, Pp 244-255 (2023)
The application of molecular tumor profiles in clinical decision making remains a challenge. To aid in the interpretation of complex biomarkers, molecular tumor boards (MTBs) have been established worldwide. In the present study, we show that a multi
Externí odkaz:
https://doaj.org/article/a6931db0fe19455eb970c982e6234b49
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundPoorly differentiated non-small cell lung cancer (NSCLC) is characteristic of high rate of distant metastasis and late stages at diagnosis. Small intestine metastasis is a rare but severe complication of lung cancer with a high rate of mort
Externí odkaz:
https://doaj.org/article/9ff9a2c059e14f239ef7124297bf5141
Autor:
Gasljevic Gorana, Boltezar Lucka, Novakovic Srdjan, Setrajcic-Dragos Vita, Jezersek-Novakovic Barbara, Kloboves-Prevodnik Veronika
Publikováno v:
Radiology and Oncology, Vol 57, Iss 2, Pp 249-256 (2023)
Diffuse large B-cell lymphoma (DLBCL) is the most common non-Hodgkin lymphoma. The expression of CD56 in DLBCL is highly unusual. Little is known about its incidence and clinical importance. So far, no genetic profiling was performed in CD56 positive
Externí odkaz:
https://doaj.org/article/30ea96c1ef474f81a6a71ae87081a1de