Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Genetic interaction network"'
Autor:
Morgan W. B. Kirzinger, Frederick S. Vizeacoumar, Bjorn Haave, Cristina Gonzalez-Lopez, Keith Bonham, Anthony Kusalik, Franco J. Vizeacoumar
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-11 (2019)
Abstract Background Synthetic lethal interactions (SLIs) that occur between gene pairs are exploited for cancer therapeutics. Studies in the model eukaryote yeast have identified ~ 550,000 negative genetic interactions that have been extensively stud
Externí odkaz:
https://doaj.org/article/c4cbce1d4b644fa1b3e16f208ea33c92
Publikováno v:
BMC Genetics, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Two key questions in understanding the genetic control of behaviors are: what genes are involved and how these genes interact. To answer these questions at a systems level, we conducted high-content profiling of Drosophila larval
Externí odkaz:
https://doaj.org/article/49ef9c75707f43febf2e61ed2602500d
Publikováno v:
Expert Review of Anti-Infective Therapy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Introduction COVID-19, a dreadful pandemic that has impacted human life like no other pathogenic invasion, has claimed the lives of over 100 million people. The need for effective treatment strategies is still a subject of intense research considerin
Autor:
Robert R. H. Anholt, Shanshan Zhou, Bahar Patlar, Murat Yılmaz, Wen Huang, Esra Durmaz, Michael M. Magwire, Trudy F. C. Mackay, Ergi Deniz Özsoy, Güzin Emecen
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 10 (2021)
G3: Genes|Genomes|Genetics
G3: Genes|Genomes|Genetics
Epistasis—gene–gene interaction—is common for mutations with large phenotypic effects in humans and model organisms. Epistasis impacts quantitative genetic models of speciation, response to natural and artificial selection, genetic mapping, and
Autor:
Bjorn Haave, Franco J. Vizeacoumar, Morgan W. B. Kirzinger, Cristina Gonzalez-Lopez, Anthony Kusalik, Frederick S. Vizeacoumar, Keith Bonham
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-11 (2019)
BMC Medical Genomics
BMC Medical Genomics
Background Synthetic lethal interactions (SLIs) that occur between gene pairs are exploited for cancer therapeutics. Studies in the model eukaryote yeast have identified ~ 550,000 negative genetic interactions that have been extensively studied, lead
Akademický článek
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Publikováno v:
Molecular Biology and Evolution
Although it is generally accepted that eukaryotic gene order is not random, the basic principles of gene arrangement on a chromosome remain poorly understood. Here, we extended existing population genetics theories that were based on two-locus models
Publikováno v:
BMC Genetics, Vol 18, Iss 1, Pp 1-11 (2017)
BMC Genetics
BMC Genetics
Background Two key questions in understanding the genetic control of behaviors are: what genes are involved and how these genes interact. To answer these questions at a systems level, we conducted high-content profiling of Drosophila larval locomotor
Akademický článek
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Akademický článek
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