Zobrazeno 1 - 10
of 1 189
pro vyhledávání: '"Genetic alteration"'
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background The corticotropin-releasing hormone-binding protein (CRHBP) plays a crucial role in regulating corticotropin release. Little is known about the role of CRHBP, a major regulator of neuroendocrine, autonomic, and stress adaptation,
Externí odkaz:
https://doaj.org/article/56c2fc7d236241bea2f0368292ef1369
Publikováno v:
مطالعات فقه و حقوق اسلامی, Vol 16, Iss 35, Pp 7-28 (2024)
In the modern era, with the rapid advancement of science, genetic engineering has provided a suitable foundation for producing transgenic animals to achieve important scientific objectives. However, despite the increasing production of these organism
Externí odkaz:
https://doaj.org/article/7985ec32c9fa4a4a84a333da560b75d3
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-15 (2024)
Abstract Background Synaptotagmin 11 (SYT11) plays a pivotal role in neuronal vesicular trafficking and exocytosis. However, no independent prognostic studies have focused on various cancers. In this study, we aimed to summarize the clinical signific
Externí odkaz:
https://doaj.org/article/3b49f7f404c241bc8ce1301a136b400a
Publikováno v:
Pharmacological Research, Vol 206, Iss , Pp 107292- (2024)
Nutrient bioavailability in the tumor microenvironment plays a pivotal role in tumor proliferation and metastasis. Among these nutrients, glutamine is a key substance that promotes tumor growth and proliferation, and its downstream metabolite asparag
Externí odkaz:
https://doaj.org/article/a615d48076ca45d4851d2d98647b381c
Autor:
Zedan Zhao, Ruyu Wang, Ruixue Wang, Jialing Song, Fengjun Ma, Huafeng Pan, Cuiyun Gao, Deqiang Wang, Xuemei Chen, Xiangzhen Fan
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-17 (2024)
Abstract Recent evidence has shed light on the significant role of FANCD2 in cancer initiation, development, and progression. However, a comprehensive pan-cancer analysis of FANCD2 has been lacking. In this study, we have conducted a thorough investi
Externí odkaz:
https://doaj.org/article/cf36e2d0c5ce4cbbb4cd4e17ccff455f
Autor:
Alexandra-Maria HOZA, Andreea-Denisa PATRASCU, Maria-Cristina ORLOV-SLAVU, Ruxandra HOROMNEA, Cornelia NITIPIR
Publikováno v:
Modern Medicine, Vol 30, Iss 4, Pp 269-281 (2023)
Objectives: Treatment of patients with non-small cell lung cancer continues to evolve and the discovery and approval of tyrosine kinase inhibitors in patients with NSCLC and targetable alterations brought an important contribution in treating these p
Externí odkaz:
https://doaj.org/article/d7367b90f2014d11a9361303c211db74
Autor:
Tan Junyin, Feng Ronghao
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 195-305 (2023)
Combined cancer immunotherapy and targeted therapy have proven to be effective against various cancers and therefore have recently become the focus of cancer research. Signal transducer and activator of transcription 3 (STAT3) is a member of the STAT
Externí odkaz:
https://doaj.org/article/8ce686443c8e4cf2b2b0110a7bf2b142
Autor:
Haiyan Gu, Jingnan Wang, Wenwen Ran, Guangqi Li, Shasha Hu, Han Zhao, Xiaonan Wang, Jigang Wang
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract Anaplastic thyroid carcinoma (ATC) is the most advanced and aggressive thyroid cancer, and poorly differentiated thyroid carcinoma (PDTC) lacks anaplastic histology but has lost architectural and cytologic differentiation. Only a few studies
Externí odkaz:
https://doaj.org/article/4850bb6b85f446b296371c523a705f93
Publikováno v:
Global Medical Genetics, Vol 10, Iss 02, Pp 123-128 (2023)
Acute myeloid leukemia (AML) is an immensely heterogeneous disease characterized by the clonal growth of promyelocytes or myeloblasts in bone marrow as well as in peripheral blood or tissue. Enhancement in the knowledge of the molecular biology of ca
Externí odkaz:
https://doaj.org/article/0eca5b7c1d0f43e2b55d3fcd58aaeb16
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12929-12942 (2023)
Abstract Objectives Reporting the clinicopathological information of thyroid cancer (TC) patients from a central medical center of east China, and constructing the nomogram predicting lymph node metastasis (LNM). Methods We collected the patients who
Externí odkaz:
https://doaj.org/article/b7feb4da593149f0b60130a926a0a424