Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Genetic Frontotemporal dementia Initiative"'
Autor:
Alberto Benussi, Enrico Premi, Mario Grassi, Antonella Alberici, Valentina Cantoni, Stefano Gazzina, Silvana Archetti, Roberto Gasparotti, Giorgio G. Fumagalli, Arabella Bouzigues, Lucy L. Russell, Kiran Samra, David M. Cash, Martina Bocchetta, Emily G. Todd, Rhian S. Convery, Imogen Swift, Aitana Sogorb-Esteve, Carolin Heller, John C. van Swieten, Lize C. Jiskoot, Harro Seelaar, Raquel Sanchez-Valle, Fermin Moreno, Robert Jr. Laforce, Caroline Graff, Matthis Synofzik, Daniela Galimberti, James B. Rowe, Mario Masellis, Maria Carmela Tartaglia, Elizabeth Finger, Rik Vandenberghe, Alexandre Mendonça, Pietro Tiraboschi, Chris R. Butler, Isabel Santana, Alexander Gerhard, Isabelle Le Ber, Florence Pasquier, Simon Ducharme, Johannes Levin, Sandro Sorbi, Markus Otto, Alessandro Padovani, Jonathan D. Rohrer, Barbara Borroni, Genetic Frontotemporal dementia Initiative (GENFI)
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The Genetic Frontotemporal Initiative Staging Group has proposed clinical criteria for the diagnosis of prodromal frontotemporal dementia (FTD), termed mild cognitive and/or behavioral and/or motor impairment (MCBMI). The objectiv
Externí odkaz:
https://doaj.org/article/13a74e32930c440d9a0c8f0b5b590de2
Autor:
Emma L. van der Ende, Carolin Heller, Aitana Sogorb-Esteve, Imogen J. Swift, David McFall, Georgia Peakman, Arabella Bouzigues, Jackie M. Poos, Lize C. Jiskoot, Jessica L. Panman, Janne M. Papma, Lieke H. Meeter, Elise G. P. Dopper, Martina Bocchetta, Emily Todd, David Cash, Caroline Graff, Matthis Synofzik, Fermin Moreno, Elizabeth Finger, Raquel Sanchez-Valle, Rik Vandenberghe, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, James B. Rowe, Chris Butler, Simon Ducharme, Alexander Gerhard, Adrian Danek, Johannes Levin, Yolande A. L. Pijnenburg, Markus Otto, Barbara Borroni, Fabrizio Tagliavini, Alexandre de Mendonça, Isabel Santana, Daniela Galimberti, Sandro Sorbi, Henrik Zetterberg, Eric Huang, John C. van Swieten, Jonathan D. Rohrer, Harro Seelaar, the Genetic Frontotemporal Dementia Initiative (GENFI)
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-13 (2022)
Abstract Background Neuroinflammation is emerging as an important pathological process in frontotemporal dementia (FTD), but biomarkers are lacking. We aimed to determine the value of complement proteins, which are key components of innate immunity,
Externí odkaz:
https://doaj.org/article/319fc84ce3124ac6ae190548e67faa37
Autor:
Sofia Bergström, Linn Öijerstedt, Julia Remnestål, Jennie Olofsson, Abbe Ullgren, Harro Seelaar, John C. van Swieten, Matthis Synofzik, Raquel Sanchez-Valle, Fermin Moreno, Elizabeth Finger, Mario Masellis, Carmela Tartaglia, Rik Vandenberghe, Robert Laforce, Daniela Galimberti, Barbara Borroni, Chris R. Butler, Alexander Gerhard, Simon Ducharme, Jonathan D. Rohrer, Anna Månberg, Caroline Graff, Peter Nilsson, on behalf of the Genetic Frontotemporal Dementia Initiative (GENFI)
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-14 (2021)
Abstract Background A detailed understanding of the pathological processes involved in genetic frontotemporal dementia is critical in order to provide the patients with an optimal future treatment. Protein levels in CSF have the potential to reflect
Externí odkaz:
https://doaj.org/article/4c79ff7f1a074b35826ced4f2779339c
Autor:
Lize C. Jiskoot, Martina Bocchetta, Jennifer M. Nicholas, David M. Cash, David Thomas, Marc Modat, Sebastien Ourselin, Serge A.R.B. Rombouts, Elise G.P. Dopper, Lieke H. Meeter, Jessica L. Panman, Rick vanMinkelen, Emma L. van derEnde, Laura Donker Kaat, Yolande A.L. Pijnenburg, Barbara Borroni, Daniela Galimberti, Mario Masellis, Maria Carmela Tartaglia, James Rowe, Caroline Graff, Fabrizio Tagliavini, Giovanni B. Frisoni, Robert Laforce Jr, Elizabeth Finger, Alexandre deMendonça, Sandro Sorbi, on behalf of the Genetic Frontotemporal dementia Initiative (GENFI), Janne M. Papma, John C. vanSwieten, Jonathan D. Rohrer
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 5, Iss 9, Pp 1025-1036 (2018)
Abstract Objective We aimed to investigate mutation‐specific white matter (WM) integrity changes in presymptomatic and symptomatic mutation carriers of the C9orf72, MAPT, and GRN mutations by use of diffusion‐weighted imaging within the Genetic F
Externí odkaz:
https://doaj.org/article/5ea32abf654c46c99d65c871dd01a86f
Autor:
Sandro Sorbi, Vince D. Calhoun, James B. Rowe, Isabelle Le Ber, Matthis Synofzik, Roberto Gasparotti, Martina Bocchetta, Enrico Premi, Dave Cash, Alexandre de Mendonça, Armin Iraji, Johannes Levin, Stefano Gazzina, A. Danek, Lize C. Jiskoot, Marcello Giunta, Alexander Gerhard, Markus Otto, Raquel Sánchez-Valle, Emily Todd, Genetic Frontotemporal dementia Initiative, Isabel Santana, Silvana Archetti, Rhian S Convery, Robert Laforce, Srinivas Rachakonda, Florence Pasquier, Fermin Moreno, John C. van Swieten, Georgia Peakman, Elizabeth Finger, Jonathan D. Rohrer, Christopher C Butler, Daniela Galimberti, Alberto Benussi, Carmela Tartaglia, Rik Vandenberghe, Caroline Graff, Mario Masellis, Fabrizio Tagliavini, Barbara Borroni, Simon Ducharme
Publikováno v:
Neurobiology of Aging, 108, 155-167. Elsevier Inc.
The presymptomatic brain changes of granulin (GRN) disease, preceding by years frontotemporal dementia, has not been fully characterized. New approaches focus on the spatial chronnectome can capture both spatial network configurations and their dynam
Autor:
Öijerstedt, L, Andersson, C, Jelic, V, van Swieten, JC, Jiskoot, LC, Seelaar, H, Borroni, B, Sanchez-Valle, R, Moreno, F, Laforce Jr, R, Synofzik, M, Galimberti, D, Rowe, JB, Masellis, M, Tartaglia, MC, Finger, E, Vandenberghe, R, de Mendonca, A, Tagliavini, F, Santana, I, Ducharme, S, Butler, CR, Gerhard, A, Levin, J, Danek, A, Otto, M, Frisoni, G, Ghidoni, R, Sorbi, S, Rohrer, JD, Graff, C, Genetic Frontotemporal Dementia Initiative (GENFI), Bocchetta, M
Supplemental material is available at https://jnnp.bmj.com/content/jnnp/93/3/336/DC1/embed/inline-supplementary-material-1.pdf?download=true . This work was supported by grants from SRC/VR 529-2014-7504, VR 2015-02926, VR 2018-02754, VR 2019-02248: J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______900::45f0fde118e61c6521e64b56edff4da0
https://bura.brunel.ac.uk/handle/2438/25721
https://bura.brunel.ac.uk/handle/2438/25721
Autor:
Wilke, Carlo, Reich, Selina, van Swieten, John C, Borroni, Barbara, Sanchez-Valle, Raquel, Moreno, Fermin, Laforce, Robert, Graff, Caroline, Galimberti, Daniela, Rowe, James B, Masellis, Mario, Tartaglia, Maria C, Finger, Elizabeth, Vandenberghe, Rik, de Mendonça, Alexandre, Tagliavini, Fabrizio, Santana, Isabel, Ducharme, Simon, Butler, Chris R, Gerhard, Alexander, Levin, Johannes, Danek, Adrian, Otto, Markus, Frisoni, Giovanni, Ghidoni, Roberta, Sorbi, Sandro, Bocchetta, Martina, Todd, Emily, Kuhle, Jens, Barro, Christian, Genetic Frontotemporal dementia Initiative (GENFI), Rohrer, Jonathan D, Synofzik, Matthis, Nicholas, Jennifer M
OBJECTIVE: Although the presymptomatic stages of frontotemporal dementia (FTD) provide a unique chance to delay or even prevent neurodegeneration by early intervention, they remain poorly defined. Leveraging a large multicenter cohort of genetic FTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::c9de6a77867f9f0787eb22985672b2a2
Autor:
Christopher C Butler, Johannes Levin, Maria Carmela Tartaglia, Markus Otto, Alain Dagher, Genetic Frontotemporal dementia Initiative, Lize C. Jiskoot, Mario Masellis, Vincent Bazinet, James B. Rowe, Mahsa Dadar, Adrian Danek, Isabel Santana, Robert Laforce, Sandro Sorbi, Fermin Moreno, Simon Ducharme, Daniela Galimberti, Alexandre de Mendonça, Bratislav Misic, Rik Vandenberghe, John C. van Swieten, Raquel Sánchez-Valle, Caroline Graff, Harro Seelaar, Barbara Borroni, D. Louis Collins, Ana L. Manera, Golia Shafiei, Matthis Synofzik, Alexander Gerhard, Fabrizio Tagliavini, Jonathan D. Rohrer, Frontotemporal Lobar Degeneration Neuroimaging Initiative, Elizabeth Finger
Connections among brain regions allow pathological perturbations to spread from a single source region to multiple regions. Patterns of neurodegeneration in multiple diseases, including behavioral variant of frontotemporal dementia (bvFTD), resemble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e49d39f4a957e68d2e0b05d9c0ad60
https://doi.org/10.1101/2021.08.24.457538
https://doi.org/10.1101/2021.08.24.457538
Autor:
Mahsa Dadar, Isabel Santana, Alexandre de Mendonça, Raquel Sánchez-Valle, Fermin Moreno, Christopher C Butler, Frontotemporal Lobar Degeneration Neuroimaging Initiative, Jonathan D. Rohrer, Sandro Sorbi, Fabrizio Tagliavini, Daniela Galimberti, Roberta Ghidoni, Elizabeth Finger, Mario Masellis, Rik Vandenberghe, Robert Laforce, Ana L. Manera, A. Danek, Alexander Gerhard, Simon Ducharme, John C. van Swieten, Maria Carmela Tartaglia, Matthis Synofzik, D. Louis Collins, James B. Rowe, Genetic Frontotemporal dementia Initiative, Barbara Borroni, Johannes Levin, Markus Otto, Caroline Graff, Giovanni B. Frisoni
INTRODUCTIONBrain structural imaging is paramount for the diagnosis of behavioral variant of frontotemporal dementia (bvFTD), but it has low sensitivity leading to erroneous or late diagnosis.METHODSA total of 515 subjects from two different bvFTD da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b6fb1e55ca505e35dabd1261e8b7db
https://doi.org/10.1101/2019.12.19.883462
https://doi.org/10.1101/2019.12.19.883462
Autor:
Bocchetta, Martina, Todd, Emily G, Peakman, Georgia, Cash, David M, Convery, Rhian S, Russell, Lucy L, Thomas, David L, Eugenio Iglesias, Juan, Van Swieten, John C, Jiskoot, Lize C, Seelaar, Harro, Borroni, Barbara, Galimberti, Daniela, Sanchez-Valle, Raquel, Laforce, Robert, Moreno, Fermin, Synofzik, Matthis, Graff, Caroline, Masellis, Mario, Carmela Tartaglia, Maria, Rowe, James B, Vandenberghe, Rik, Finger, Elizabeth, Tagliavini, Fabrizio, De Mendonça, Alexandre, Santana, Isabel, Butler, Chris R, Ducharme, Simon, Gerhard, Alexander, Danek, Adrian, Levin, Johannes, Otto, Markus, Sorbi, Sandro, Le Ber, Isabelle, Pasquier, Florence, Rohrer, Jonathan D, Genetic Frontotemporal Dementia Initiative (GENFI)
BACKGROUND: Studies have previously shown evidence for presymptomatic cortical atrophy in genetic FTD. Whilst initial investigations have also identified early deep grey matter volume loss, little is known about the extent of subcortical involvement,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a156631afe710d763e0979c8d8812571