Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Genesys Giraldo"'
Autor:
Genesys Giraldo, Christopher Janus
Publikováno v:
Brain research bulletin. 166
Mouse models that replicate facets of human neurological diseases are often used at the pre-clinical stage to better understand the underlying mechanisms of a disease and test the target engagement of potential therapeutic interventions. We recently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c4632f5360542ff67bf9f28a1297cd
https://pubmed.ncbi.nlm.nih.gov/33147520
https://pubmed.ncbi.nlm.nih.gov/33147520
Autor:
Genesys Giraldo, Toshiyuki Fukada, Shintaro Hojyo, Ralf Weiskirchen, Armin Garcia, Jessica Schrier, Supak Jenkitkasemwong, Mitchell D. Knutson, Christopher Janus, Benoit I. Giasson, Adenike Akinyode, Elizabeth Paulus
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Solute carrier family 39, member 14 (SLC39A14) is a transmembrane transporter that can mediate the cellular uptake of zinc, iron, and manganese (Mn). Studies of Slc39a14 knockout (Slc39a14-/-) mice have documented that SLC39A14 is required for system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2b75f5f2dc5420a3776dcc66bcb4b03
https://doi.org/10.1073/pnas.1720739115
https://doi.org/10.1073/pnas.1720739115
Publikováno v:
Neurobiology of aging. 65
Parkinson's disease manifests as a progressive movement disorder with underlying degeneration of dopaminergic neurons in the substantia nigra, consequent depletion of dopamine levels, and the accumulation of Lewy bodies in the brain. Because α-synuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7d211b4e80e40d3220106f420ac425
https://pubmed.ncbi.nlm.nih.gov/29477894
https://pubmed.ncbi.nlm.nih.gov/29477894