In Vivo Tumorigenesis, Osteolytic Sarcomas, and Tumorigenic Cell Lines from Transgenic Mice Expressing the Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax Viral Oncogene.

Autor: Lanigan LG; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio; Tox Path Specialists, a StageBio Company, Fredrick, Maryland., Hildreth BE 3rd; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama., Dirksen WP; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Simmons JK; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Martin CK; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio; Department of Pathology and Microbiology, University of Prince Edward Island, Atlantic Veterinary College, Prince Edward Island, Canada., Werbeck JL; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Thudi NK; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Papenfuss TL; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Boyaka PN; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Toribio RE; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio., Ward JM; Global VetPathology, Montgomery Village, Maryland., Weilbaecher KN; Division of Molecular Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Rosol TJ; Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio; Department of Biomedical Sciences, Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio. Electronic address: rosolt@ohio.edu.

Publikováno v: The American journal of pathology [Am J Pathol] 2021 Feb; Vol. 191 (2), pp. 335-352. Date of Electronic Publication: 2020 Nov 09.

Impact of host immunity on HTLV-1 pathogenesis: potential of Tax-targeted immunotherapy against ATL.

Autor: Kannagi M; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan. kann.impt@tmd.ac.jp., Hasegawa A; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan., Nagano Y; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan., Kimpara S; Department of Immunotherapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.; Department of Immunology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Suehiro Y; Department of Hematology, National Kyushu Cancer Center, Fukuoka, Japan.

Publikováno v: Retrovirology [Retrovirology] 2019 Aug 22; Vol. 16 (1), pp. 23. Date of Electronic Publication: 2019 Aug 22.

Coevolution of HTLV-1-HBZ, Tax, and proviral load with host IRF-1 and CCNA-2 in HAM/TSP patients.

Autor: Saffari M; Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran., Rahimzada M; Immunology Research Center, Inflammation and Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran., Mirhosseini A; Immunology Research Center, Inflammation and Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran., Ghezaldasht SA; Blood Borne Infections Research Center, Academic Center for Education, Culture and Research (ACECR), Razavi Khorasan Branch, Mashhad, Iran., Valizadeh N; Immunology Research Center, Inflammation and Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran., Moshfegh M; Atiye Hospital, Saadat Abad, Tehran, Iran., Moradi MT; Medical Plants Research Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran. Electronic address: Mtmoradi65@gmail.com., Rezaee SA; Immunology Research Center, Inflammation and Inflammatory Diseases Division, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address: Rezaeer@mums.ac.ir.

Publikováno v: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2022 Sep; Vol. 103, pp. 105337. Date of Electronic Publication: 2022 Jul 12.

[Development of Tax-redirected T-cell immunotherapy using TCR gene transduction in patients with ATL].

Autor: Tanaka Y; Division of Hematology, Saitama Medical Center, Jichi Medical University., Kanda Y

Publikováno v: [Rinsho ketsueki] The Japanese journal of clinical hematology [Rinsho Ketsueki] 2015 Jul; Vol. 56 (7), pp. 815-24.

The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation.

Autor: Mohanty S; Department of Microbiology and Immunology, Penn State College School of Medicine, Hershey, Pennsylvania, United States of America., Han T; W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America., Choi YB; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America., Lavorgna A; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America., Zhang J; Department of Microbiology and Immunology, Penn State College School of Medicine, Hershey, Pennsylvania, United States of America., Harhaj EW; Department of Microbiology and Immunology, Penn State College School of Medicine, Hershey, Pennsylvania, United States of America.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2020 Dec 23; Vol. 16 (12), pp. e1008504. Date of Electronic Publication: 2020 Dec 23 (Print Publication: 2020).