Zobrazeno 1 - 10 of 55 pro vyhledávání: '"Geneeskunde: algemeen"'
1
Native LDL potentiate TNF alpha and IL-8 production by human mononuclear cells
Autor: Mihai G. Netea, Jos W. M. van der Meer, Anton F. H. Stalenhoef, Liesbeth E. H. Jacobs, Peter H.G.M. Willems, Anneke Hijmans, Pierre N.M. Demacker, Trees J.G. Verver-Jansen, Lambertus H.J. van Tits, Joost G. J. Hoenderop, Bart Jan Kullberg
Publikováno v: Journal of Lipid Research, 43, 1065-1071
Journal of Lipid Research (Online), 43, 1065-1071
Journal of Lipid Research (Online), 43, 1065-1071. Lipid research inc
Journal of Lipid Research, 43, 7, pp. 1065-1071
Journal of Lipid Research, Vol 43, Iss 7, Pp 1065-1071 (2002)
Contains fulltext : 185418.pdf (Publisher’s version ) (Open Access) Native LDL (nLDL) increases expression of adhesion molecules on endothelial cells through induction of Ca(2+) mobilization. Ca(2+) mobilization is also involved in the induction of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d9de6ea30edd2cc0781502d62b1261
https://doi.org/10.1194/jlr.m100254-jlr200
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2
Hormonal regulation of phospholipase D activity in Ca(2+) transporting cells of rabbit connecting tubule and cortical collecting duct
Autor: Joost G. J. Hoenderop, Linda van der Heijden, Peter H.G.M. Willems, Remko R. Bosch, Jan Joep H.H.M. De Pont, René J. M. Bindels
Publikováno v: Biochimica et Biophysica Acta. Molecular Cell Research, 1538, 2-3, pp. 329--38
Biochimica et Biophysica Acta. Molecular Cell Research, 1538, 329--38
Biochimica et Biophysica Acta. Molecular Cell Research, 1538, 329-338
Biochimica et Biophysica Acta. Molecular Cell Research, 1538, 2-3, pp. 329-338
Item does not contain fulltext Phospholipase D (PLD) is distributed widely in mammalian tissues where it is believed to play an important role in the regulation of cell functions and cell fate by a variety of extracellular signals. In this study, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee6a98da6f90e5f8a5a89ce3e7e348c
https://hdl.handle.net/2066/29935
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3
Principles of Signal Detection in Pharmacovigilance
Autor: Frank W. J. Gribnau, Antoine C. G. Egberts, I. R. Edwards, Yechiel A. Hekster, Ronald H. B. Meyboom, F. H. P. De Koning
Publikováno v: Drug Safety, 16, 355-365
Drug Safety, 16, 6, pp. 355-365
Adverse drug effects are manifold and heterogenous. Many situations may hamper the signalling (i.e. the detection of early warning signs) of adverse effects and new signals often differ from previous experiences. Signals have qualitative and quantita
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a27c9d3827e3408774c8e16566d9a
https://doi.org/10.2165/00002018-199716060-00002
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4
Long term beta-1 adrenergic blockade restores adrenomedullary activity in primary hypertension
Autor: Cees J. Tack, Theo Thien, Jacques J. Willemsen, Paul Smits, Marie-Cecile Jacobs, Jacques W.M. Lenders
Publikováno v: Journal of Cardiovascular Pharmacology, 30, 338-342
Journal of Cardiovascular Pharmacology, 30, pp. 338-342
Journal of Cardiovascular Pharmacology, 30, 3, pp. 338-342
Summary: in this; study we examined the effects of long-term treatment of 19 patients with primary hypertension with the sr adrenoceptor antagonist atenolol on norepinephrine and epi­ nephrine kinetics, at rest and during sympathoadrenal stimula­ t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2aac1639e793b53ec24ae9d6683001
https://hdl.handle.net/2066/24316
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5
Antigen specificity of anti-nuclear antibodies complexed to nucleosomes determines glomerular basement membrane binding in vivo
Autor: W. Tamboer, K. Kramers, Jhm Berden, Marc Monestier, Ruud J.T. Smeenk, T. P. M. Rijke, Gilbert J. Fournié, M. C. J. Van Bruggen, B. Walgreen
Publikováno v: European Journal of Immunology, 27, pp. 1564-1569
European Journal of Immunology, 27, 6, pp. 1564-1569
European Journal of Immunology, 27, 1564-1569
Monoclonal anti-nuclear antibodies which are complexed to nucleosomes are able to bind to the glomerular basement membrane (GBM) in vivo, whereas purified antibodies do not bind. The positively charged histone moieties in the nucleosome are-responsib
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5113e92029be4fb0f51d66ad64f51f
https://hdl.handle.net/2066/25112
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6
Good practice in the postmarketing surveillance of medicines
Autor: Meyboom, R.H.B.
Publikováno v: Pharmacy World and Science, 19, 4, pp. 186-190
Pharmacy World and Science, 19, 186-190
Contains fulltext : 25930___.PDF (Publisher’s version ) (Open Access)
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https://hdl.handle.net/2066/25930
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7
Autoimmunity against nucleosomes and lupus nephritis
Autor: Bruggen, M.C.J. van, Kramers, C., Berden, J.H.M.
Publikováno v: Annales de Médecine Interne, 147, 485-489
Annals of Internal Medicine C.2, 147, pp. 485-489
Annals of Internal Medicine C.2, 147, 485-489
Annales de Médecine Interne, 147, 7, pp. 485-489
Item does not contain fulltext
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https://hdl.handle.net/2066/25338
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8
Dual Reactivity of Several Monoclonal Anti-nucleosome Autoantibodies for Double-stranded DNA and a Short Segment of Histone H3
Autor: Jhm Berden, P. Richalet-Sécordel, Christine Stemmer, K. Kramers, Sylviane Muller, M. van Bruggen
Publikováno v: Journal of Biological Chemistry, 271, 21257-21261
Journal of Biological Chemistry, 271, pp. 21257-21261
Journal of Biological Chemistry, 271, 35, pp. 21257-21261
We have shown previously that four IgG monoclonal autoantibodies (mAbs) reacted in ELISA with both double-stranded (ds) DNA and peptide 83-100 of histone H3. The peptide 83-100 contains a cysteine residue at position 96 and readily dimerizes at pH 7-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a8060a01ddd46f58828b087ebb9622
https://doi.org/10.1074/jbc.271.35.21257
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9
Molecular cloning and expression of a cyclic AMP activated chloride conductance regulator : a novel ATP-binding cassette transporter
Autor: Frans G. M. Russel, Peter M.T. Deen, M.A. van Kuijck, Andreas E. Busch, René J. M. Bindels, R.A.M.H. van Aubel, Florian Lang, C.H. van Os
Publikováno v: Proceedings of the National Academy of Sciences USA, 93, 5401-5406
Proceedings of the National Academy of Science USA, 93, 11, pp. 5401-5406
Proceedings of the National Academy of Science USA, 93, 5401-5406. Natl acad sciences
Proceedings of the National Academy of Science USA, 93, 5401-5406
Proceedings of the National Academy of Science USA, 93, pp. 5401-5406
Proceedings of the National Academy of Sciences USA, 9, pp. 5401-5406
Proceedings of the National Academy of Sciences USA, 93, pp. 5401-5406
Proceedings of the National Academy of Sciences USA, 9, 5401-5406
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ATP-regulated, cAMP-activated chloride channel located in the apical membrane of many epithelial secretory cells. Here we report cloning of a cAMP-activated epithelial basolateral chlor
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https://hdl.handle.net/2066/22512
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10
Renal excretion and accumulation kinetics of 2-methylbenzoylglycine in the isolated perfused rat kidney
Autor: Frans G. M. Russel, Rosalinde Masereeuw, Miek M. Moons
Publikováno v: Journal of Pharmacy and Pharmacology, 48, 560-565
Journal of Pharmacy and Pharmacology, 48, 6, pp. 560-565
ResearcherID
Journal of Pharmacy and Pharmacology, 48, pp. 560-565
The effect of protein binding on kidney function has been studied by investigating the renal accumulation and secretion of the hippurate analogue 2-methylbenzoylglycine in the isolated perfused rat kidney in the absence and presence of bovine serum a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a162a26c6e9b10db9fffef3e3739c21b
https://hdl.handle.net/2066/22899
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