Zobrazeno 1 - 10
of 711
pro vyhledávání: '"Gene-expression microarray"'
Autor:
Noritaka Wakasugi, Harumasa Takano, Mitsunari Abe, Nobukatsu Sawamoto, Toshiya Murai, Toshiki Mizuno, Teruyuki Matsuoka, Ryo Yamakuni, Hirooki Yabe, Hiroshi Matsuda, Takashi Hanakawa, Parkinson’s and Alzheimer’s disease Dimensional Neuroimaging Initiative (PADNI)
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundDopamine transporter single-photon emission computed tomography (DAT-SPECT) is a crucial tool for evaluating patients with Parkinson’s disease (PD). However, its implication is limited by inter-site variability in large multisite clinical
Externí odkaz:
https://doaj.org/article/9750fd33b2e04876bf209159987c138a
Gene expression can serve as a powerful predictor for disease progression and other phenotypes. Consequently, microarrays, which capture gene expression genome-wide, have been used widely over the past two decades to derive biomarker signatures for t
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A90143
https://tud.qucosa.de/api/qucosa%3A90143/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A90143/attachment/ATT-0/
Autor:
Gringmuth, Marieke, Walther, Jenny, Greiser, Sebastian, Touissant, Magali, Schwalm, Benjamin, Kool, Marcel, Kortmann, Rolf-Dieter, Glasow, Annegret, Patties, Ina
Children with high-risk SHH/TP53-mut and Group 3 medulloblastoma (MB) have a 5-year overall survival of only 40%. Innovative approaches to enhance survival while preventing adverse effects are urgently needed. We investigated an innovative therapy ap
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A89163
https://ul.qucosa.de/api/qucosa%3A89163/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A89163/attachment/ATT-0/
Autor:
Patricia Martinez-Morales, Irene Morán Cruz, Lorena Roa-de la Cruz, Paola Maycotte, Juan Salvador Reyes Salinas, Victor Javier Vazquez Zamora, Claudia Teresita Gutierrez Quiroz, Alvaro Jose Montiel-Jarquin, Verónica Vallejo-Ruiz
Publikováno v:
PeerJ, Vol 9, p e12081 (2021)
Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased expression of glycogenes involved in sialylation and sialylated glycans. He
Externí odkaz:
https://doaj.org/article/f20ffa4857484911b3876016e54a14ee
Autor:
Shunichi Oka, Xiaoyan Li, Fengzhu Zhang, Nitesh Tewari, Ri Ma, Liangjun Zhong, Makoto Makishima, Yi Liu, Ujjal K. Bhawal
Publikováno v:
Biochemistry and Biophysics Reports, Vol 25, Iss , Pp 100894- (2021)
MicroRNAs are emerging as critical post-transcriptional modulators in bone remodeling, regulating the functions of osteoblasts and osteoclasts. Intercellular crosstalk between osteoblasts and osteoclasts is mediated by miR-21 that controls the bone h
Externí odkaz:
https://doaj.org/article/604a09570b624bcd8236aa8f19930fb3
Akademický článek
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Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The development of new drugs is multidisciplinary and systematic work. High-throughput techniques based on “-omics” have driven the discovery of biomarkers in diseases and therapeutic targets of drugs. A transcriptome is the complete set of all R
Externí odkaz:
https://doaj.org/article/f9a44a1ed3184d09810950f682b81904
Autor:
Aurora Crespo-Jara, Maria Carmen Redal-Peña, Elena Maria Martinez-Navarro, Manuel Sureda, Francisco Jose Fernandez-Morejon, Francisco J. Garcia-Cases, Ramon Gonzalez Manzano, Antonio Brugarolas
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract Background Building a universal genomic signature predicting the intensity of FDG uptake in diverse metastatic tumors may allow us to understand better the biological processes underlying this phenomenon and their requirements of glucose upt
Externí odkaz:
https://doaj.org/article/45ba77917604499e97bc4ce9029022ed
Publikováno v:
Journal of the Royal Statistical Society. Series B (Statistical Methodology), 2004 Jan 01. 66(4), 815-849.
Externí odkaz:
https://www.jstor.org/stable/3647651
Autor:
Fraley, Chris, Raftery, Adrian E.
Publikováno v:
Journal of the American Statistical Association, 2002 Jun 01. 97(458), 611-631.
Externí odkaz:
https://www.jstor.org/stable/3085676