Zobrazeno 1 - 10
of 2 861
pro vyhledávání: '"Gene set enrichment"'
Autor:
Xinxin Zhang, Caiping Liu, Luqian Cao, Hongguang Tang, Haiyun Jiang, Changjing Hu, Xuehong Dong, Feiyang Zhou, Kunming Qin, Qiang Liu, Jinyang Shen, Yue Zhou
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract This study explored the comorbid mechanisms between Crohn’s disease (CD) and chronic obstructive pulmonary disease (COPD) using bioinformatics analysis. From the Gene Expression Omnibus (GEO) microarray dataset, 349 common differentially e
Externí odkaz:
https://doaj.org/article/f69266ff4a7640df9e5b4f9ba6271cdd
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Sepsis-induced myopathy is one of the serious complications of sepsis, which severely affects the respiratory and peripheral motor systems of patients, reduces their quality of life, and jeopardizes their lives, as evidenced by muscle atroph
Externí odkaz:
https://doaj.org/article/4186f508e4be4fdcb0d3b6ee00576d56
Autor:
Cezary Turek, Márton Ölbei, Tamás Stirling, Gergely Fekete, Ervin Tasnádi, Leila Gul, Balázs Bohár, Balázs Papp, Wiktor Jurkowski, Eszter Ari
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Traditional gene set enrichment analyses are typically limited to a few ontologies and do not account for the interdependence of gene sets or terms, resulting in overcorrected p-values. To address these challenges, we introduce mulea, an R p
Externí odkaz:
https://doaj.org/article/4173539fd2534cf08947a5381c37bf10
Autor:
Lilei Xu, Jiaqi Ma, Chuanlong Zhou, Zhe Shen, Kean Zhu, Xuewen Wu, Yang Chen, Ting Chen, Xianming Lin
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Knee osteoarthritis (KOA) is a common chronic joint disease globally. Synovial inflammation plays a pivotal role in its pathogenesis, preceding cartilage damage. Identifying biomarkers in osteoarthritic synovial tissues holds promise for ear
Externí odkaz:
https://doaj.org/article/9eafdbdfc06c48d8a0e95ff08b457ddf
Publikováno v:
Open Medicine, Vol 19, Iss 1, Pp 1301-14 (2024)
This study aims to address the substantive issue of lacking reliable prognostic biomarkers in hepatocellular carcinoma (HCC) by investigating the relationship between TP53-inducible glycolysis and apoptosis regulator (TIGAR) and HCC prognosis using T
Externí odkaz:
https://doaj.org/article/ea4291dd8c2a43b1a0ca4402c04a7a74
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 449-461 (2024)
Osteoarthritis (OA) is a comprehensive joint disorder. The specific genes that trigger OA and the strategies for its effective management are not fully understood. This study focuses on identifying key genes linked to iron metabolism that could influ
Externí odkaz:
https://doaj.org/article/100f935f32f84ffe829be285de8a7c20
Autor:
Kangjie Xu, Dongling Li, Kangkang Ji, Yanhua Zhang, Minglei Zhang, Hai Zhou, Xuefeng Hou, Jian Jiang, Zihang Zhang, Hua Dai, Hang Sun
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background Kidney renal clear cell carcinoma (KIRC) represents a significant proportion of renal cell carcinomas and is characterized by high aggressiveness and poor prognosis despite advancements in immunotherapy. Disulfidptosis, a novel ce
Externí odkaz:
https://doaj.org/article/f3121fe162444d5e9add7c00713dd2bc
Autor:
Éva Kereszturi
Publikováno v:
Molecular Brain, Vol 17, Iss 1, Pp 1-9 (2024)
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by social and communication difficulties, along with repetitive behaviors. While genetic factors play a significant role in ASD, the precise genetic landscape rem
Externí odkaz:
https://doaj.org/article/3c063ff8463f4f2397d7e3548720e023
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Ulcerative colitis (UC) is a chronic inflammatory bowel disease with intricate pathogenesis and varied presentation. Accurate diagnostic tools are imperative to detect and manage UC. This study sought to construct a robust diagnostic model u
Externí odkaz:
https://doaj.org/article/56322a7658f0435e87c56644e2a0b0ff
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 7, Pp 6328-6345 (2024)
Although sows do not directly enter the market, they play an important role in piglet breeding on farms. They consume large amounts of feed, resulting in a significant environmental burden. Pig farms can increase their income and reduce environmental
Externí odkaz:
https://doaj.org/article/a9a0022b17e144a6b0153f22e5475bd1