Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Gene regulatory elements"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 357-370 (2023)
Riboswitches are functional RNA elements that regulate gene expression by directly detecting metabolites. Twenty years have passed since it was first discovered, researches on riboswitches are becoming increasingly standardized and refined, which cou
Externí odkaz:
https://doaj.org/article/84a473b3bd044623bf52af257db1e39a
Autor:
Soheil Yousefi, Ruizhi Deng, Kristina Lanko, Eva Medico Salsench, Anita Nikoncuk, Herma C. van der Linde, Elena Perenthaler, Tjakko J. van Ham, Eskeatnaf Mulugeta, Tahsin Stefan Barakat
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-27 (2021)
Abstract Background Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation, and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is a complex organ that is s
Externí odkaz:
https://doaj.org/article/8bd08f49ac6c42ddbc775328a55f61d6
Publikováno v:
Вавиловский журнал генетики и селекции, Vol 25, Iss 3, Pp 344-355 (2021)
The correct deployment of genetic programs for development and differentiation relies on finely coordinated regulation of specific gene sets. Genomic regulatory elements play an exceptional role in this process. There are few types of gene regulatory
Externí odkaz:
https://doaj.org/article/013c0d6e95c24ef2b880031a3933f469
Autor:
Jonathan J. Froehlich, Bora Uyar, Margareta Herzog, Kathrin Theil, Petar Glažar, Altuna Akalin, Nikolaus Rajewsky
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108988- (2021)
Summary: How regulatory sequences control gene expression is fundamental for explaining phenotypes in health and disease. Regulatory elements must ultimately be understood within their genomic environment and development- or tissue-specific contexts.
Externí odkaz:
https://doaj.org/article/ce5cdaf5f7314b4398c31f465e7e436e
Publikováno v:
eLife, Vol 8 (2019)
RNA splicing is an essential part of eukaryotic gene expression. Although the mechanism of splicing has been extensively studied in vitro, in vivo kinetics for the two-step splicing reaction remain poorly understood. Here, we combine transient transc
Externí odkaz:
https://doaj.org/article/30692b75cc824b83bf3d9429a5992660
Autor:
Bates, Mallory N.
21% of U.S adults experienced mental illnesses in 2020. Nearly 1 in 4 active- duty military personnel showed signs of mental health conditions in 2014 [89]. Mental health can be identified in the body by different biomarkers. These biomarkers potenti
Autor:
Eskeatnaf Mulugeta, Eva Medico Salsench, Elena Perenthaler, Herma C. van der Linde, Anita Nikoncuk, Ruizhi Deng, Kristina Lanko, Soheil Yousefi, Tahsin Stefan Barakat, Tjakko J. van Ham
Publikováno v:
Genome Medicine, 13(1):162. BioMed Central Ltd.
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-27 (2021)
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-27 (2021)
Background Non-coding regulatory elements (NCREs), such as enhancers, play a crucial role in gene regulation, and genetic aberrations in NCREs can lead to human disease, including brain disorders. The human brain is a complex organ that is susceptibl
Publikováno v:
Viruses, Vol 10, Iss 3, p 116 (2018)
Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long
Externí odkaz:
https://doaj.org/article/ba1c4bf7ccca4f97818d3a06c57b7f5c
Autor:
Ivan eMerelli, Fabio eTordini, Maurizio eDrocco, Marco eAldinucci, Pietro eLiò, Luciano eMilanesi
Publikováno v:
Frontiers in Genetics, Vol 6 (2015)
The representation, integration and interpretation of omic data is a complex task, in particular considering the huge amount of information that is daily produced in molecular biology laboratories all around the world. The reason is that sequencing d
Externí odkaz:
https://doaj.org/article/1380895a68c640aab416f51738b961b4