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pro vyhledávání: '"Gene panel selection"'
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Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Targeted spatial transcriptomics hold particular promise in analyzing complex tissues. Most such methods, however, measure only a limited panel of transcripts, which need to be selected in advance to inform on the cell types or processes bei
Externí odkaz:
https://doaj.org/article/5400b0ad82bd43918520150a06bfd4c4
Autor:
Ana I. Casas, Ahmed A. Hassan, Quirin Manz, Christian Wiwie, Pamela Kleikers, Javier Egea, Manuela G. López, Markus List, Jan Baumbach, Harald H. H. W. Schmidt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Differential gene expression normalised to a single housekeeping (HK) is used to identify disease mechanisms and therapeutic targets. HK gene selection is often arbitrary, potentially introducing systematic error and discordant results. Here
Externí odkaz:
https://doaj.org/article/f695aab77cc14bc98cf8a63fc3f54100
Autor:
Casas, Ana I.1,2 (AUTHOR) anaisabel.casasguijarro@uk-essen.de, Hassan, Ahmed A.2 (AUTHOR), Manz, Quirin3 (AUTHOR), Wiwie, Christian4 (AUTHOR), Kleikers, Pamela2 (AUTHOR), Egea, Javier5,6 (AUTHOR), López, Manuela G.6 (AUTHOR), List, Markus7 (AUTHOR), Baumbach, Jan3 (AUTHOR), Schmidt, Harald H. H. W.2 (AUTHOR) hschmidt@ppmlab.net
Publikováno v:
Scientific Reports. 7/19/2022, Vol. 12 Issue 1, p1-12. 12p.
Autor:
Zhang Y; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Department of Neurobiology, Duke University, Durham, NC, USA., Petukhov V; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Biederstedt E; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Que R; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Zhang K; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA., Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 24. Date of Electronic Publication: 2023 Mar 24.
Publikováno v:
bioRxiv
Targeted spatial transcriptomics hold particular promise in analysis of complex tissues. Most such methods, however, measure only a limited panel of transcripts, which need to be selected in advance to inform on the cell types or processes being stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b8b2b3f08b3a1f9c300b7a79d5d7de
https://europepmc.org/articles/PMC10054990/
https://europepmc.org/articles/PMC10054990/
Autor:
Linga, BalaSubramani Gattu1,2 (AUTHOR), Mohammed, Sawsan G. A. A.3 (AUTHOR), Farrell, Thomas1 (AUTHOR), Rifai, Hilal Al4 (AUTHOR), Al-Dewik, Nader1,2,4,5,6 (AUTHOR) nader.al-dewik@kingston.ac.uk, Qoronfleh, M. Walid7 (AUTHOR) nader.al-dewik@kingston.ac.uk
Publikováno v:
Cancers. Jun2024, Vol. 16 Issue 11, p2017. 32p.
Autor:
Zhang, Weiliang, Meng, Zhen, Wang, Dongjie, Wu, Min, Liu, Kunpeng, Zhou, Yuanchun, Xiao, Meng
Recent advancements in single-cell genomics necessitate precision in gene panel selection to interpret complex biological data effectively. Those methods aim to streamline the analysis of scRNA-seq data by focusing on the most informative genes that
Externí odkaz:
http://arxiv.org/abs/2406.07418
Publikováno v:
Frontiers in Genetics; 2024, p1-7, 7p
Autor:
Josephs, Katherine S.1,2 (AUTHOR) kjosephs@imperial.ac.uk, Seaby, Eleanor G.3,4,5 (AUTHOR), May, Philippa2,6 (AUTHOR), Theotokis, Pantazis1,2,7 (AUTHOR), Yu, Jing8 (AUTHOR), Andreou, Avgi9 (AUTHOR), Sinclair, Hannah10 (AUTHOR), Morris-Rosendahl, Deborah1,2 (AUTHOR), Thomas, Ellen R. A.11 (AUTHOR), Ennis, Sarah3 (AUTHOR), Roberts, Angharad M.1,2,12 (AUTHOR), Ware, James S.1,2,7 (AUTHOR)
Publikováno v:
Genome Medicine. 10/29/2024, Vol. 16 Issue 1, p1-22. 22p.