Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Gene network analysis"'
Autor:
Ali Ammarellou
Publikováno v:
BMC Genomic Data, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Pungency of garlic (Allium sativum L.) is generated from breakdown of the alk(en)yl cysteine sulphoxide (CSO), alliin and its subsequent breakdown to allicin under the activity of alliinase (All). Based on recent evidence, two other importan
Externí odkaz:
https://doaj.org/article/f7d6b459cd9e40a0bbdcff17273eb35b
Autor:
Simon T. Hui, Lili Gong, Chantle Swichkow, Montgomery Blencowe, Dorota Kaminska, Graciel Diamante, Calvin Pan, Meet Dalsania, Samuel W. French, Clara E. Magyar, Päivi Pajukanta, Jussi Pihlajamäki, Kristina I. Boström, Xia Yang, Aldons J. Lusis
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 943-960 (2023)
Background & Aims: Nonalcoholic steatohepatitis (NASH) is a complex disease involving both genetic and environmental factors in its onset and progression. We analyzed NASH phenotypes in a genetically diverse cohort of mice, the Hybrid Mouse Diversity
Externí odkaz:
https://doaj.org/article/17f948e14a694036a2a9724de594eb98
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background Vector-borne viral diseases threaten human and wildlife worldwide. Vectors are often viewed as a passive syringe injecting the virus. However, to survive, replicate and spread, viruses must manipulate vector biology. While most ve
Externí odkaz:
https://doaj.org/article/4043beb2970240379d921f28549e6baa
Akademický článek
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Akademický článek
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MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illness
Autor:
Christopher J. Walsh, Carlos Escudero King, Muskan Gupta, Pamela J. Plant, Margaret J. Herridge, Sunita Mathur, Pingzhao Hu, Judy Correa, Sameen Ahmed, Anne Bigot, Claudia C. dosSantos, Jane Batt, Submitted on behalf of the MusclE and Nerve Dysfunction (MEND)‐ICU Group and Canadian Critical Care Translational Biology Group (CCCTBG)
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 2, Pp 1262-1276 (2022)
Abstract Background Intensive care unit (ICU)‐acquired weakness is characterized by muscle atrophy and impaired contractility that may persist after ICU discharge. Dysregulated muscle repair and regeneration gene co‐expression networks are presen
Externí odkaz:
https://doaj.org/article/f8215a3d765742de99fa1db9d3550ea5
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-12 (2022)
Abstract Background Atherosclerosis is one of the major causes of cardiovascular disease. It is characterized by the accumulation of atherosclerotic plaque in arteries under the influence of inflammatory responses, proliferation of smooth muscle cell
Externí odkaz:
https://doaj.org/article/30cff343366148f8a41296999f921df1
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Objective: To investigate the effect of Zhilong Huoxue Tongyu capsule (ZLH) in the treatment of cerebral ischemia–reperfusion injury and determine the underlying molecular network mechanism.Methods: The treatment effect of Zhilong Huoxue Tongyu cap
Externí odkaz:
https://doaj.org/article/46331fce41694f0382966c5714a1d316
Autor:
Sinjini Patra, Nilanjan Sahu, Shivam Saxena, Biswaranjan Pradhan, Saroj Kumar Nayak, Anasuya Roychowdhury
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
BackgroundDysbiosis/imbalance in the gut microbial composition triggers chronic inflammation and promotes colorectal cancer (CRC). Modulation of the gut microbiome by the administration of probiotics is a promising strategy to reduce carcinogenic inf
Externí odkaz:
https://doaj.org/article/10e02e80127b4b1e814819a9b5f98482
Autor:
Daniel Lancour, Josée Dupuis, Richard Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard C. Schellenberg, Mark Crovella, Lindsay A. Farrer, Simon Kasif
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background Identifying and understanding the functional role of genetic risk factors for Alzheimer disease (AD) has been complicated by the variability of genetic influences across brain regions and confounding with age-related neurodegenera
Externí odkaz:
https://doaj.org/article/a030cad76a4049c59eb4f3bca41ab8df