Zobrazeno 1 - 10
of 5 468
pro vyhledávání: '"Gene expression profiles"'
Autor:
Arnob Sarker, Md. Abdul Aziz, Md. Bayazid Hossen, Md. Manir Hossain Mollah, Al-Amin, Md. Nurul Haque Mollah
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Glioblastoma (GBM) is the most malignant brain cancer and one of the leading causes of cancer-related death globally. So, identifying potential molecular signatures and associated drug molecules are crucial for diagnosis and therapies of GBM
Externí odkaz:
https://doaj.org/article/80f63320735546b0ba5ea1f954adf3c1
Autor:
Juanita Mellet, Candice L. Hendricks, Voula Stivaktas, Chrisna Durandt, Melvin A. Ambele, Michael S. Pepper
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Ex vivo haematopoietic stem/progenitor cell (HSPCs) expansion constitutes an important area of research, and has the potential to improve access to umbilical cord blood (UCB) as a source of stem cells for haematopoietic stem cell
Externí odkaz:
https://doaj.org/article/79229c6b5d14402b8a5116d7950c3316
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
BackgroundThe study aimed to investigate the molecular mechanisms underlying kidney stones by analyzing gene expression profiles. They focused on identifying differentially expressed genes (DEGs), performing gene set enrichment analysis (GSEA), weigh
Externí odkaz:
https://doaj.org/article/5caaa27fbfc745be913a3a3233312377
Autor:
Barbara Meier-Schiesser, MD, PhD, Christine Zecha, MD, Sarah Zierold, MD, Isabel Kolm, MD, Magdalena Röckel, MD, Waltraud Fröhlich, Nora Mittag, MD, Christina Schmitt, MD, Joerg Kumbrink, PhD, Jessica C. Hassel, MD, Carola Berking, MD, Dorothee Nashan, MD, Lars Einar French, MD, Julio Vera-González, PhD, Reinhard Dummer, MD, Katrin Kerl-French, MD, Lucie Heinzerling, MD, MPH
Publikováno v:
JAAD International, Vol 15, Iss , Pp 157-164 (2024)
Background: Although highly efficacious, immune checkpoint inhibitors induce a multitude of immune-related adverse events including lichenoid skin reactions (irLP) that are often therapy-resistant. Objectives: To compare the clinical, histological, a
Externí odkaz:
https://doaj.org/article/51030e89392948efa51788f904e90ecb
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Insects rely on sophisticated sensitive chemosensory systems to sense their complex chemical environment. This sensory process involves a combination of odorant receptors (ORs), gustatory receptors (GRs) and ionotropic receptors (
Externí odkaz:
https://doaj.org/article/39fd285675f546bba66d1c85d8ed3e73
Autor:
Ahmad Bereimipour, Saeed Karimi, Mohammad Faranoush, Amir Abbas Hedayati Asl, Monireh sadat Miri, Leila Satarian, Sara Taleahmad
Publikováno v:
Cell Journal, Vol 26, Iss 4, Pp 250-258 (2024)
Objective: Intraocular retinoblastoma (RB) is common in kids. Although the cause of this disease is a mutation in theRB1 gene, the formed cancerous mass in different patients is seen in non-invasive states, limited to the ocular cavityor in invasive
Externí odkaz:
https://doaj.org/article/77830a24e1f14c1788fe79d565bdc1f0
Autor:
Ehsan Jangholi, Hoda Ahmari Tehran, Afsaneh Ghasemi, Mohammad Hoseinian, Sina Firoozi, Seyed Mohammad Ghodsi, Mona Tamaddon, Ahmad Bereimipour, Mahmoudreza Hadjighassem
Publikováno v:
Cancer Reports, Vol 7, Iss 7, Pp n/a-n/a (2024)
Abstract Background Glioblastoma (GBM) is a malignant brain tumor that frequently occurs alongside other central nervous system (CNS) conditions. The secretome of GBM cells contains a diverse array of proteins released into the extracellular space, i
Externí odkaz:
https://doaj.org/article/cb43dbebff0a4079b74ea0f880f67030
Autor:
Di Zhao, Ling-feng Zeng, Gui-hong Liang, Ming-hui Luo, Jian-ke Pan, Yao-xing Dou, Fang-zheng Lin, He-tao Huang, Wei-yi Yang, Jun Liu
Publikováno v:
Bone & Joint Research, Vol 13, Iss 2, Pp 66-82 (2024)
Aims: This study aimed to explore the biological and clinical importance of dysregulated key genes in osteoarthritis (OA) patients at the cartilage level to find potential biomarkers and targets for diagnosing and treating OA. Methods: Six sets of ge
Externí odkaz:
https://doaj.org/article/b60ce0aea5ea460e947004a8e6a74ff2
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Geoherb usually represents high-quality medicinal herbs with better clinical therapeutic effects, and elucidating the geoherbalism is essential for the quality improvement of traditional Chinese Medicine. However, few researches were conduct
Externí odkaz:
https://doaj.org/article/47d094e1037c41d1ab5b138151c70cb4
Autor:
Min-Jing Chang, Qi-Fan Feng, Jia-Wei Hao, Ya-Jing Zhang, Rong Zhao, Nan Li, Yu-Hui Zhao, Zi-Yi Han, Pei-Feng He, Cai-Hong Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundFor Rheumatoid Arthritis (RA), a long-term chronic illness, it is essential to identify and describe patient subtypes with comparable goal status and molecular biomarkers. This study aims to develop and validate a new subtyping scheme that
Externí odkaz:
https://doaj.org/article/7db1a3b40cc848deba230b1ac643d55c