Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Gene Uenishi"'
Autor:
Tom Humphreys, Keith Weiser, Asuka Arimoto, Akane Sasaki, Gene Uenishi, Brent Fujimoto, Takeshi Kawashima, Kekoa Taparra, Janos Molnar, Noriyuki Satoh, Yusuke Marikawa, Kuni Tagawa
Publikováno v:
Frontiers in Ecology and Evolution, Vol 10 (2022)
Hemichordate enteropneust worms regenerate extensively in a manner that resembles the regeneration for which planaria and hydra are well known. Although hemichordates are often classified as an extant phylogenetic group that may hold ancestral deuter
Externí odkaz:
https://doaj.org/article/248d53880b084102a19dd8e7c0ea03fe
Publikováno v:
Bio-Protocol, Vol 10, Iss 13 (2020)
Pluripotent stem cells (PSCs) have the potential to provide homogeneous cell populations of T cells that can be grown at a clinical scale and genetically engineered to meet specific clinical needs. OP9-DLL4, a stromal line ectopically expressing the
Externí odkaz:
https://doaj.org/article/5d83271cd826498f857d8b03b7154431
Autor:
Mi Ae Park, Akhilesh Kumar, Ho Sun Jung, Gene Uenishi, Oleg V. Moskvin, James A. Thomson, Igor I. Slukvin
Publikováno v:
Cell Reports, Vol 23, Iss 8, Pp 2467-2481 (2018)
Summary: Understanding the pathways guiding the development of definitive hematopoiesis with lymphoid potential is essential for advancing human pluripotent stem cell (hPSC) technologies for the treatment of blood diseases and immunotherapies. In the
Externí odkaz:
https://doaj.org/article/00af84ab4fee4184b14e731e3db90a86
Autor:
Ho Sun Jung, Gene Uenishi, Akhilesh Kumar, Mi Ae Park, Matt Raymond, Dustin Fink, Ethan McLeod, Igor Slukvin
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 401-405 (2016)
Human embryonic stem cell line WA01 was genetically modified using zinc-finger nucleases and the PiggyBac/transponson system to introduce a fluorescence reporter for VE-cadherin (VEC; tdTomato) and CD43 (eGFP). Phenotypic and functional assays for pl
Externí odkaz:
https://doaj.org/article/479b161d2d9d44378c88ee76755e5633
Autor:
Gene Uenishi, Derek Theisen, Jeong-Hee Lee, Akhilesh Kumar, Matt Raymond, Maxim Vodyanik, Scott Swanson, Ron Stewart, James Thomson, Igor Slukvin
Publikováno v:
Stem Cell Reports, Vol 3, Iss 6, Pp 1073-1084 (2014)
The recent identification of hemogenic endothelium (HE) in human pluripotent stem cell (hPSC) cultures presents opportunities to investigate signaling pathways that are essential for blood development from endothelium and provides an exploratory plat
Externí odkaz:
https://doaj.org/article/bd92bb855e1a4330afb9cf9af031b8e6
Autor:
Rohini Radia, Gene Uenishi, Maria H. Gilleece, Adrian Bloor, Laurie S. Larson, Diana Drier, James E. Griffin, Igor I. Slukvin, Amit R. Patel, Kilian Kelly, David T Yeung, John E.J. Rasko, Derek J. Hei
Publikováno v:
Nature Medicine. 26:1720-1725
The therapeutic potential of donor-derived mesenchymal stromal cells (MSCs) has been investigated in diverse diseases1, including steroid-resistant acute graft versus host disease (SR-aGvHD)2. However, conventional manufacturing approaches are hamper
Publikováno v:
Bio Protoc
Pluripotent stem cells (PSCs) have the potential to provide homogeneous cell populations of T cells that can be grown at a clinical scale and genetically engineered to meet specific clinical needs. OP9-DLL4, a stromal line ectopically expressing the
Autor:
Mi Ae Park, Irene M. Ong, Kran Suknuntha, Gene Uenishi, James A. Thomson, Igor I. Slukvin, Yoon Jung Choi, Ho Sun Jung, Peng Liu, Matthew Raymond
Publikováno v:
Cell reports
SUMMARY SOX17 has been implicated in arterial specification and the maintenance of hematopoietic stem cells (HSCs) in the murine embryo. However, knowledge about molecular pathways and stage-specific effects of SOX17 in humans remains limited. Here,
Autor:
Dustin M. Fink, Mi Ae Park, Matt Raymond, Ethan McLeod, Akhilesh Kumar, Ho Sun Jung, Igor I. Slukvin, Gene Uenishi
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 401-405 (2016)
Human embryonic stem cell line WA0 1 was genetically modified using zinc-finger nucleases and the PiggyBac/transponson system to introduce a fluorescence reporter for VE-cadherin (VEC; tdTomato) and CD43 (eGFP). Phenotypic and functional assays for p
Autor:
Igor I. Slukvin, Gene Uenishi
Publikováno v:
Experimental hematology. 71
Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the de novo production of blood cells for transfusion, immunotherapies, and transplantation. However, even with advanced hematopoietic differentiation methods, the pri