Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Gene Therapy/ methods"'
This publication is an overview of the exciting discoveries in the field of AIDS which were discussed at the workshop ‘Development and Applications of Vaccines and Gene Therapy in AIDS'(Naples, June 1995). Various articles present the latest advanc
Publikováno v:
International Journal of Pharmaceutics. 413:174-183
Oral delivery of gene therapeutics would facilitate treatment of local intestinal disease, including colon cancer and inflammatory bowel disease, thus avoiding invasive surgery. The aims of this study were to investigate; if the orientation of the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452345cc59823c2b57e7447b45e01956
https://doi.org/10.1016/j.ijpharm.2011.04.021
https://doi.org/10.1016/j.ijpharm.2011.04.021
Publikováno v:
Molecular Therapy. 18:477-490
Lentiviral vectors (LVs) have emerged as potent and versatile vectors for ex vivo or in vivo gene transfer into dividing and nondividing cells. Robust phenotypic correction of diseases in mouse models has been achieved paving the way toward the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017d6b77ca87252d723e9b9c125a7f45
https://doi.org/10.1038/mt.2009.319
https://doi.org/10.1038/mt.2009.319
Publikováno v:
British Journal of Dermatology; Vol 161
Gene therapy has the potential to treat devastating inherited diseases for which there is little hope of finding a conventional cure. These include lethal diseases, like immunodeficiencies or several metabolic disorders, or conditions associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e23f4cac22c064d78b33164d7b7dba
https://doi.org/10.1111/j.1365-2133.2009.09243.x
https://doi.org/10.1111/j.1365-2133.2009.09243.x
Autor:
Thomas Moll, Wolfgang Langhans, Panteleimon Giannakopoulos, Irene Garcia-Gabay, Philippe G. Vallet, Fabienne de Bilbao, Denis Arsenijevic
Publikováno v:
Journal of Neurochemistry, Vol. 110, No 1 (2009) pp. 12-22
Early studies showed that the administration of the anti-inflammatory cytokine interleukin-10 (IL10) protects against permanent middle cerebral artery occlusion (MCAO) in mice. In this study, transgenic mice expressing murine IL10 (IL10T) directed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b678b87e61b37cb8e3b9601d9f51ef13
https://doi.org/10.1111/j.1471-4159.2009.06098.x
https://doi.org/10.1111/j.1471-4159.2009.06098.x
Autor:
W. Holzgreve, M. Lessl
The title'Stem Cells from Cord Blood, In Utero Stem Cell Develop ment, and Transplantation-Inclusive Gene Therapy'suggests that more than one topic is combined in one workshop. Indeed, at first glance the recovery of stem cells from cord blood has
Autor:
Danielle Baetens, Patrick Aebischer, Navid Alizadeh, Denys Montandon, Michael S. Pepper, Chris Rinsch, Pierre Dominique Quinodoz, Brigitte Pittet
Publikováno v:
Gene Therapy, Vol. 8, No 7 (2001) pp. 523-33
Stimulating angiogenesis by gene transfer approaches offers the hope of treating tissue ischemia which is untreatable by currently practiced techniques of vessel grafting and bypass surgery. Vascular endothelial growth factor (VEGF) and basic fibrobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257ec00e46c89944156eb4178c94a968
https://doi.org/10.1038/sj.gt.3301436
https://doi.org/10.1038/sj.gt.3301436
Publikováno v:
Gene Therapy. 8:58-66
The transplantation of genetically engineered cells faces limitations associated with host immunity. Allogeneic cells are typically rejected in response to inherent histo-incompatibility. Even autologous cells can induce an immune response toward ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::438e65026ad0967bf3643da71aa3abd6
https://doi.org/10.1038/sj.gt.3301356
https://doi.org/10.1038/sj.gt.3301356
Publikováno v:
Transplantation, Vol. 89, No 1 (2010) pp. 127-129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53b64da18a035d9907dedeae174fb916
https://doi.org/10.1097/tp.0b013e3181c28118
https://doi.org/10.1097/tp.0b013e3181c28118
Autor:
Hans Yssel, Louise Swainson, Wilhelm Friedrich, Naomi Taylor, M Boyer, Marcos Steinberg, Klaus Schwarz, Nelly Noraz
Publikováno v:
Gene Therapy
Gene Therapy, Nature Publishing Group, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, Nature Publishing Group, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Gene Therapy, 2000, 7 (16), pp.1392--400. ⟨10.1038/sj.gt.3301249⟩
Humans lacking the ZAP-70 protein tyrosine kinase present with an absence of CD8+ T cells and defective CD4+ T cells in the periphery. This severe combined immunodeficiency is fatal unless treated by allogeneic bone marrow transplantation. However, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf555fe728d9f80cd926fb434cd34b8
https://doi.org/10.1038/sj.gt.3301249
https://doi.org/10.1038/sj.gt.3301249