Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

Autor: Igor Bazov, Oleg Krishtal, Jan Mulder, Hiroyuki Watanabe, Dineke S. Verbeek, Georgy Bakalkin, Tatiana Yakovleva, Henrik Druid, Kanar Alkass, G. V. Gerashchenko, Craig A. Stockmeier, Olga Kononenko, Åsa Fex Svenningsen, Oleg Dyachok, Malin Andersson, Grazyna Rajkowska

Publikováno v: Kononenko, O, Bazov, I, Watanabe, H, Gerashchenko, G, Dyachok, O, Verbeek, D S, Alkass, K, Druid, H, Andersson, M, Mulder, J, Fex Svenningsen, Å, Rajkowska, G, Krishtal, O, Yakovleva, T & Bakalkin, G 2017, ' Opioid precursor protein isoform is targeted to the cell nuclei in the human brain ', B B A-General Subjects, vol. 1861, no. 2, pp. 246–255 . https://doi.org/10.1016/j.bbagen.2016.11.002
Biochimica et Biophysica Acta-General Subjects, 1861(2), 246-255. ELSEVIER SCIENCE BV

Background: Neuropeptide precursors are traditionally viewed as proteins giving rise to small neuropeptide molecules. Prodynorphin (PDYN) is the precursor protein to dynorphins, endogenous ligands for the kappa-opioid receptor. Alternative mRNA splic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d38f283d45a80c7a35bd83cb2a5e60f
https://hdl.handle.net/11370/647f138f-3c80-465e-bbc8-68d27d8752ec

Ectopic expression of systemic RNA interference defective protein in embryonic stem cells

Autor: Jennifer C. Moore, Suk Ying Tsang, Rika Van Huizen, Ronald A. Li, Camie W.Y. Chan

Publikováno v: Biochemical and Biophysical Research Communications. 357:480-486

RNA interference (RNAi), a post-transcriptional gene silencing mechanism originally described in Caenorhabditis elegans, involves sequence-specific mRNA degradation mediated by double-stranded RNAs (dsRNAs). Passive dsRNA uptake has been uniquely obs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281b1d1413f1cf98c88cdd17c5f378ad
https://doi.org/10.1016/j.bbrc.2007.03.187

RNA interference-mediated URG4 gene silencing diminishes cyclin D1 mRNA expression in HepG2 cells

Autor: Gok D, Cetinkaya A, Feitelson Ma, Yavuz Dodurga, Satiroglu-Tufan Nl

Publikováno v: Genetics and molecular research : GMR. 9(3)

Up-regulated gene 4 (URG4), stimulated by HBxAg, is a novel gene located on chromosome 7 (7p13). The full-length URG4 clone is 3.607 kb and encodes a polypeptide of 922 amino acids, with a molecular weight of 104 kDa (GeneID: 55665). It promotes cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c4ac5a8e75fdd4b2e92e53a2d91159
https://pubmed.ncbi.nlm.nih.gov/20714998

Two means of transcriptional reactivation within heterochromatin

Autor: Probst, Aline V., Fransz, Paul F., Paszkowski, Jerzy, Mittelsten Scheid, Ortrun

Publikováno v: Plant Journal
Plant Journal, Wiley, 2003, 33 (4), pp.743-9
Plant Journal, Vol. 33, No 4 (2003) pp. 743-9

International audience; DNA methylation levels and specific histone modifications of chromatin in interphase nuclei are taken as an indicator of transcriptional activity or silencing. Arabidopsis mutants impaired in maintenance of transcriptional gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6bb8d2d5f44dc15526a5943b0f6b333b
https://pubmed.ncbi.nlm.nih.gov/12609046