Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Gene Kurosawa"'
Autor:
Nobunao Ikewaki, Masaru Iwasaki, Gene Kurosawa, Kosagi-Sharaf Rao, Johant Lakey-Beitia, Senthilkumar Preethy, Samuel JK Abraham
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 8, Pp 2808-2813 (2021)
Conventional vaccines to combat COVID-19 through different approaches are at various stages of development. The complexity of COVID-19 such as the potential mutations of the virus leading to antigenic drift and the uncertainty on the duration of the
Externí odkaz:
https://doaj.org/article/0478231d12be4362a48404c124b550a2
Autor:
Kadalraja Raghavan, Vidyasagar Devaprasad Dedeepiya, Ramesh Shankar Kandaswamy, Mangaleswaran Balamurugan, Nobunao Ikewaki, Tohru Sonoda, Gene Kurosawa, Masaru Iwasaki, Senthilkumar Preethy, Samuel JK Abraham
Publikováno v:
Brain and Behavior, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Introduction Poor sleep quality is a major problem in patients with autism spectrum disorder (ASD), and is attributed to low melatonin levels. Melatonin supplementation is recommended; however, its effectiveness varies. β‐Glucans have pre
Externí odkaz:
https://doaj.org/article/a3dd354d70684f05aa1f22dda11962e5
Autor:
Takuma Hayashi, Naoki Yamamoto, Gene Kurosawa, Kaori Tajima, Mariko Kondo, Noriko Hiramatsu, Yu Kato, Miho Tanaka, Hisateru Yamaguchi, Yoshikazu Kurosawa, Harumoto Yamada, Nobuyuki Fujita
Publikováno v:
Cancers, Vol 14, Iss 23, p 5829 (2022)
Osteosarcoma is a malignant tumor that produces neoplastic bone or osteoid osteoma. In human multicentric osteosarcoma (HMOS), a unique variant of human osteosarcoma (HOS), multiple bone lesions occur simultaneously or asynchronously before lung meta
Externí odkaz:
https://doaj.org/article/611f8d268ed64a70ab6fc96d8a16bb81
Autor:
Fukiko Hihara, Hiroki Matsumoto, Mitsuyoshi Yoshimoto, Takashi Masuko, Yuichi Endo, Chika Igarashi, Tomoko Tachibana, Mitsuhiro Shinada, Ming-Rong Zhang, Gene Kurosawa, Aya Sugyo, Atsushi B. Tsuji, Tatsuya Higashi, Hiroaki Kurihara, Makoto Ueno, Yukie Yoshii
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5807 (2022)
Peritoneal dissemination of pancreatic cancer has a poor prognosis. We have reported that intraperitoneal radioimmunotherapy using a 64Cu-labeled antibody (64Cu-ipRIT) is a promising adjuvant therapy option to prevent this complication. To achieve pe
Externí odkaz:
https://doaj.org/article/0d760c3e34b0475c92ee299e4da2927e
Autor:
Nobuko Ohshima, Yoshitaka Iba, Ritsuko Kubota-Koketsu, Ayami Yamasaki, Keiko Majima, Gene Kurosawa, Daisuke Hirano, Shunji Yoshida, Mototaka Sugiura, Yoshizo Asano, Yoshinobu Okuno, Yoshikazu Kurosawa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7422 (2020)
Four kinds of avian-derived H5N1 influenza virus, A/Vietnam/1194/2004 (Clade 1), A/Indonesia/5/2005 (Clade 2.1), A/Qinghai/1A/2005 (Clade 2.2), and A/Anhui/1/2005 (Clade 2.3), have been stocked in Japan for use as pre-pandemic vaccines. When a pandem
Externí odkaz:
https://doaj.org/article/a765001f8d7240acad085c7cbade5379
Autor:
Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Gene Kurosawa, Yoshikazu Kurosawa, David Alexander, Hiroyuki Tsuda, Tsuneo Saga, Tatsuya Higashi
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2304 (2020)
Background: CD73 is an ectonucleotidase regulating extracellular adenosine concentration and plays an important role in adenosine-mediated immunosuppressive pathways. The efficacy of CD73-targeted therapy depends on the expression levels of CD73; the
Externí odkaz:
https://doaj.org/article/fdd71911547a4c9a9af2941668e10e51
Autor:
Daisuke Hirano, Nobuko Ohshima, Ritsuko Kubota-Koketsu, Ayami Yamasaki, Gene Kurosawa, Yoshinobu Okuno, Shunji Yoshida, Yoshikazu Kurosawa
Publikováno v:
Journal of Immunology Research, Vol 2018 (2018)
We analyzed the antibody (Ab) repertoire against influenza B viruses induced by vaccination with seasonal influenza viruses in one individual who had never been vaccinated until 2009. The vaccine used in this study comprised B/Massachusetts/2/2012 (Y
Externí odkaz:
https://doaj.org/article/cab4209450984c759f6f7b33c6ca3983
Autor:
Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Mitsuru Koizumi, Yoshinori Ukai, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga, Tatsuya Higashi
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 2979 (2018)
The poor prognosis of pancreatic cancer requires the development of more effective therapy. CD147 expresses in pancreatic cancer with high incidence and has a crucial role in invasion and metastasis. We developed a fully human monoclonal antibody (05
Externí odkaz:
https://doaj.org/article/9cfcb8d526e1424eb41b6e4e1550e0c5
Autor:
Aya Sugyo, Atsushi B Tsuji, Hitomi Sudo, Maki Okada, Mitsuru Koizumi, Hirokazu Satoh, Gene Kurosawa, Yoshikazu Kurosawa, Tsuneo Saga
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123761 (2015)
Pancreatic cancer is an aggressive tumor and the prognosis remains poor. Therefore, development of more effective therapy is needed. We previously reported that 89Zr-labeled TSP-A01, an antibody against transferrin receptor (TfR), is highly accumulat
Externí odkaz:
https://doaj.org/article/b235263fd9f54e5585f3762841bd0f0d
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 11, p 1862 (2016)
In previous studies, we identified 29 tumor-associated antigens (TAAs) and isolated 488 human monoclonal antibodies (mAbs) that specifically bind to one of the 29 TAAs. In the present study, we performed histochemical analysis of 36 freshly resected
Externí odkaz:
https://doaj.org/article/288126fdbbf7407fb01fc36f9a8efd5e