Zobrazeno 1 - 10
of 254
pro vyhledávání: '"Gene E, Alexander"'
Autor:
Hyun Song, Pradyumna K. Bharadwaj, David A. Raichlen, Christian G. Habeck, Matthew D. Grilli, Matthew J. Huentelman, Georg A. Hishaw, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Homocysteine (Hcy) is a cardiovascular risk factor implicated in cognitive impairment and cerebrovascular disease but has also been associated with Alzheimer’s disease. In 160 healthy older adults (mean age = 69.66 ± 9.95 years), we sought to inve
Externí odkaz:
https://doaj.org/article/f5320eed5a0245309c690ea3f60b1ff3
Autor:
David A. Raichlen, Madeline Ally, Daniel H. Aslan, M. Katherine Sayre, Pradyumna K. Bharadwaj, Silvio Maltagliati, Mark H. C. Lai, Rand R. Wilcox, Christian G. Habeck, Yann C. Klimentidis, Gene E. Alexander
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION We examined the relationship between sedentary behavior (SB), moderate‐to‐vigorous physical activity (MVPA), and white matter hyperintensity (WMH) volumes, a common magnetic resonance imaging (MRI) marker associated with ris
Externí odkaz:
https://doaj.org/article/033fd6a5b7f84cae9863a01675336b03
Autor:
Hanna K. Hausman, Gene E. Alexander, Ronald Cohen, Michael Marsiske, Steven T. DeKosky, Georg A. Hishaw, Andrew O'Shea, Jessica N. Kraft, Yunfeng Dai, Samuel Wu, Adam J. Woods
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 283-311 (2024)
Background: Pharmacological interventions for depression and anxiety in older adults often have significant side effects, presenting the need for more tolerable alternatives. Transcranial direct current stimulation (tDCS) is a promising non-pharmacol
Externí odkaz:
https://doaj.org/article/2d17439435bf4f4baac9749fff83b8bf
Autor:
Emily J. Van Etten, Pradyumna K. Bharadwaj, Matthew D. Grilli, David A. Raichlen, Georg A. Hishaw, Matthew J. Huentelman, Theodore P. Trouard, Gene E. Alexander
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
Hippocampal volume is particularly sensitive to the accumulation of total brain white matter hyperintensity volume (WMH) in aging, but how the regional distribution of WMH volume differentially impacts the hippocampus has been less studied. In a coho
Externí odkaz:
https://doaj.org/article/61d96f3f69ff49b89b51d46b436b5c3d
Autor:
Hanna K. Hausman, Gene E. Alexander, Ronald Cohen, Michael Marsiske, Steven T. DeKosky, Georg A. Hishaw, Andrew O'Shea, Jessica N. Kraft, Yunfeng Dai, Samuel Wu, Adam J. Woods
Publikováno v:
Brain Stimulation, Vol 16, Iss 3, Pp 904-917 (2023)
Background: There is a need for effective interventions to stave off cognitive decline in older adults. Cognitive training has variably produced gains in untrained tasks and daily functioning. Combining cognitive training with transcranial direct cur
Externí odkaz:
https://doaj.org/article/4ac9d2719dc54d849b3a96051a4820c2
Autor:
Boris Cheval, Liza Darrous, Karmel W. Choi, Yann C. Klimentidis, David A. Raichlen, Gene E. Alexander, Stéphane Cullati, Zoltán Kutalik, Matthieu P. Boisgontier
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Physical activity and cognitive functioning are strongly intertwined. However, the causal relationships underlying this association are still unclear. Physical activity can enhance brain functions, but healthy cognition may also promote enga
Externí odkaz:
https://doaj.org/article/2bc33b5542bf404086e494787f3bf38d
Autor:
Hanna K. Hausman, Yunfeng Dai, Andrew O’Shea, Vanessa Dominguez, Matthew Fillingim, Kristin Calfee, Daniela Carballo, Cindy Hernandez, Sean Perryman, Jessica N. Kraft, Nicole D. Evangelista, Emily J. Van Etten, Samantha G. Smith, Pradyumna K. Bharadwaj, Hyun Song, Eric Porges, Steven T. DeKosky, Georg A. Hishaw, Michael Marsiske, Ronald Cohen, Gene E. Alexander, Samuel S. Wu, Adam J. Woods
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Background: Older adults are at a greater risk for contracting and experiencing severe illness from COVID-19 and may be further affected by pandemic-related precautions (e.g., social distancing and isolation in quarantine). However, the longitudinal
Externí odkaz:
https://doaj.org/article/0d28dc1038984b51949432b19084b439
Autor:
Hanna K. Hausman, Cheshire Hardcastle, Jessica N. Kraft, Nicole D. Evangelista, Emanuel M. Boutzoukas, Andrew O'Shea, Alejandro Albizu, Kailey Langer, Emily J. Van Etten, Pradyumna K. Bharadwaj, Hyun Song, Samantha G. Smith, Eric Porges, Georg A. Hishaw, Samuel Wu, Steven DeKosky, Gene E. Alexander, Michael Marsiske, Ronald Cohen, Adam J. Woods
Publikováno v:
Neuroimage: Reports, Vol 2, Iss 2, Pp 100085- (2022)
Minimizing head motion during functional magnetic resonance imaging (fMRI) is important for maintaining the integrity of neuroimaging data. While there are a variety of techniques to control for head motion, oftentimes, individuals with excessive in-
Externí odkaz:
https://doaj.org/article/f4cc2fea7d864b918bc7c587012653a5
Autor:
David A. Raichlen, Pradyumna K. Bharadwaj, Lauren A. Nguyen, Mary Kathryn Franchetti, Erika K. Zigman, Abigail R. Solorio, Gene E. Alexander
Publikováno v:
BMC Geriatrics, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background The ability to walk and perform cognitive tasks simultaneously is a key aspect of daily life. Performance declines in these dual-tasks may be associated with early signs of neurodegenerative disease and increased risk of falls. Th
Externí odkaz:
https://doaj.org/article/94b972f350ae48c5bef6540e27c3af0f
Autor:
Emanuel M. Boutzoukas, Andrew O'Shea, Alejandro Albizu, Nicole D. Evangelista, Hanna K. Hausman, Jessica N. Kraft, Emily J. Van Etten, Pradyumna K. Bharadwaj, Samantha G. Smith, Hyun Song, Eric C. Porges, Alex Hishaw, Steven T. DeKosky, Samuel S. Wu, Michael Marsiske, Gene E. Alexander, Ronald Cohen, Adam J. Woods
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Frontal lobe structures decline faster than most other brain regions in older adults. Age-related change in the frontal lobe is associated with poorer executive function (e.g., working memory, switching/set-shifting, and inhibitory control). The effe
Externí odkaz:
https://doaj.org/article/93a863182b9141759e27564035bc76ed