Zobrazeno 1 - 10
of 1 791
pro vyhledávání: '"Gene—gene interaction"'
Autor:
Ai-Ru Hsieh, Chen-Yu Tsai
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-11 (2024)
Abstract The supervised machine learning method is often used for biomedical relationship extraction. The disadvantage is that it requires much time and money to manually establish an annotated dataset. Based on distant supervision, the knowledge bas
Externí odkaz:
https://doaj.org/article/7d7a954fcc9048b6b569a56acaba2769
Autor:
Berenice Rivera-Paredez, Alberto Hidalgo-Bravo, Priscilla López-Montoya, Adriana Becerra‑Cervera, Nelly Patiño, Edgar Denova-Gutiérrez, Jorge Salmerón, Rafael Velázquez-Cruz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Skin pigmentation is negatively associated with circulating vitamin D (VD) concentration. Therefore, genetic factors involved in skin pigmentation could influence the risk of vitamin D deficiency (VDD). We evaluated the impact genetic varian
Externí odkaz:
https://doaj.org/article/c1cf26e8645a4c4682909b2c2bb33b59
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Objective Alcohol withdrawal syndrome (AWS) is a complex condition associated with alcohol use disorder (AUD), characterized by significant variations in symptom severity among patients. The psychological and emotional symptoms accompanying
Externí odkaz:
https://doaj.org/article/ab3cd56fae9d455595901de6a98d9fbd
Autor:
Maëva Veyssiere, Maria del Pilar Rodriguez Ordonez, Smahane Chalabi, Laetitia Michou, François Cornelis, Anne Boland, Robert Olaso, Jean-François Deleuze, Elisabeth Petit-Teixeira, Valérie Chaudru
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease caused by a combination of genetic and environmental factors. Rare variants with low predicted effects in genes participating in the same biological function might be involved in dev
Externí odkaz:
https://doaj.org/article/7325e1972e61498f86b59a1064b0e849
Autor:
Sotelo-Ramírez CE, Camarena B, Sanabrais-Jiménez MA, Zaragoza-Hoyos JU, Ordoñez-Martínez B, Escamilla-Orozco RI, Gómez-González B
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 19, Pp 2353-2361 (2023)
Carlo E Sotelo-Ramírez,1,2 Beatriz Camarena,2 Marco Antonio Sanabrais-Jiménez,2 Julio Uriel Zaragoza-Hoyos,2 Bruno Ordoñez-Martínez,2 Raul I Escamilla-Orozco,3 Beatriz Gómez-González4 1Posgrado en Biología Experimental, Universidad Autónoma M
Externí odkaz:
https://doaj.org/article/46855ed229bd401facb293d14d552473
Autor:
Jiawei Wu, Lidan Xu, Bangquan Liu, Wenjing Sun, Yuanting Hu, Yi Yang, Keer Guo, Xueyuan Jia, Haiming Sun, Jie Wu, Yun Huang, Wei Ji, Songbin Fu, Yuandong Qiao, Xuelong Zhang
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-9 (2023)
Abstract Background MSM are at high risk of HIV infection. Previous studies have shown that the cell cycle regulation plays an important role in HIV-1 infection, especially at the G2/M checkpoint. ATR, Chk1, Cdc25C and CDK1 are key genes of G2/M chec
Externí odkaz:
https://doaj.org/article/02faf79d72d44be3bcd59624e6b0cf0c
Autor:
Ziang Xu, Xinlei Chen, Xiaomeng Song, Xinxin Kong, Jiajin Chen, Yunjie Song, Maojie Xue, Lin Qiu, Mingzhu Geng, Changyue Xue, Wei Zhang, Ruyang Zhang
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract The majority of these existing prognostic models of head and neck squamous cell carcinoma (HNSCC) have unsatisfactory prediction accuracy since they solely utilize demographic and clinical information. Leveraged by autophagy-related epigenet
Externí odkaz:
https://doaj.org/article/260cab3713d84fe187bb5b9cc7144e02
Autor:
Ling Xu, Jingyi Zhang, Haibo Yang, Chengqi Cao, Ruojiao Fang, Ping Liu, Shu Luo, Binbin Wang, Kunlin Zhang, Li Wang
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
BackgroundPosttraumatic stress disorder (PTSD) and major depressive disorder (MDD) comorbidity occurs through exposure to trauma with genetic susceptibility. Neuropeptide-Y (NPY) and dopamine are neurotransmitters associated with anxiety and stress-r
Externí odkaz:
https://doaj.org/article/baa223656051490f93f79fec023f7954
Publikováno v:
IEEE Access, Vol 11, Pp 73568-73582 (2023)
Compared to single-omics data, utilizing multi-omics data helps to gain a more comprehensive understanding of the occurrence and development of cancer, which emphasizes the necessity of developing efficient multi-omics data fusion approaches. In this
Externí odkaz:
https://doaj.org/article/ce0a9e4973ab492aa1408e08ac9c9af5
Autor:
Marcus Keatinge, Matthew E. Gegg, Lisa Watson, Heather Mortiboys, Nan Li, Mark Dunning, Deepak Ailani, Hai Bui, Astrid van Rens, Dirk J. Lefeber, Anthony H. V. Schapira, Ryan B. MacDonald, Oliver Bandmann
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 6 (2023)
Externí odkaz:
https://doaj.org/article/2eda39a160ff472d9a32f0cc12287c6c