Zobrazeno 1 - 10
of 466
pro vyhledávání: '"Gene‐Jack Wang"'
Autor:
Peter Manza, Dardo Tomasi, Ehsan Shokri-Kojori, Rui Zhang, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, Michele-Vera Yonga, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The faster a drug enters the brain, the greater its addictive potential, yet the brain circuits underlying the rate dependency to drug reward remain unresolved. With simultaneous PET-fMRI we linked dynamics of dopamine signaling, brain activ
Externí odkaz:
https://doaj.org/article/623f73d6b0514209a834c48f08dca9bc
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
Background and aimsIncreasing evidence suggests that a ketogenic (high-fat, low-carbohydrate) diet (KD) intervention reduces alcohol withdrawal severity and alcohol craving in individuals with alcohol use disorder (AUD) by shifting brain energetics f
Externí odkaz:
https://doaj.org/article/ded28fcf4d4d4456a05f57db4c33f74d
Autor:
Dardo Tomasi, Peter Manza, Jean Logan, Ehsan Shokri-Kojori, Michele-Vera Yonga, Danielle Kroll, Dana Feldman, Katherine McPherson, Catherine Biesecker, Evan Dennis, Allison Johnson, Kai Yuan, Wen-Tung Wang, John A. Butman, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
Combined PET imaging and mathematical simulations reveal that the rate of dopamine increase in the striatum underlies self-reports of drug “high” in response to oral and intravenous methylphenidate challenges in humans
Externí odkaz:
https://doaj.org/article/7438493119da4cdb8fb6d112347e0e5c
Autor:
Xinyi Li, Daniel D. Langleben, Kevin G. Lynch, Gene-Jack Wang, Igor Elman, Corinde E. Wiers, Zhenhao Shi
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
BackgroundExcessive consumption of opioids is associated with impaired metabolic function including increased body mass index (BMI). Opioid antagonist naltrexone (NTX) is an effective treatment for opioid use disorder (OUD) that has the potential to
Externí odkaz:
https://doaj.org/article/cb9c2b20767a4c27a0e8403378013518
Autor:
Şükrü B. Demiral, Peter Manza, Erin Biesecker, Corinde Wiers, Ehsan Shokri-Kojori, Katherine McPherson, Evan Dennis, Allison Johnson, Dardo Tomasi, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
PET imaging in human participants revealed that D1 and D2 dopamine receptor availability was associated with eye-blink rates following treatment with oral methylphenidate, but not a placebo.
Externí odkaz:
https://doaj.org/article/eb8bf127aee141bca5ac632e6ce5563f
Autor:
Peter Manza, Ehsan Shokri-Kojori, Şükrü Barış Demiral, Corinde E. Wiers, Rui Zhang, Natasha Giddens, Katherine McPherson, Erin Biesecker, Evan Dennis, Allison Johnson, Dardo Tomasi, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-9 (2022)
Joint PET and MRI analyses of cortical D1 and D2 dopamine receptors in healthy adults provide a framework for understanding how dopamine-boosting drugs alter brain function.
Externí odkaz:
https://doaj.org/article/d0d017b2d0eb48b2a0cd101f9bb95750
Autor:
Leah Vines, Diana Sotelo, Allison Johnson, Evan Dennis, Peter Manza, Nora D. Volkow, Gene-Jack Wang
Publikováno v:
Intelligent Medicine, Vol 2, Iss 2, Pp 61-68 (2022)
Ketamine, a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist, has been exclusively used as an anesthetic in medicine and has led to new insights into the pathophysiology of neuropsychiatric disorders. Clinical studies have shown that lo
Externí odkaz:
https://doaj.org/article/af0aadd13bf84944ab6dd407a56135a7
Autor:
Peter Manza, Ehsan Shokri-Kojori, Şükrü Barış Demiral, Rui Zhang, Evan Dennis, Allison Johnson, Leah Vines, Diana Sotelo, Dardo Tomasi, Gene-Jack Wang, Nora D. Volkow
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/2921c8762d4f4c9c9d9aa79756783fac
Autor:
Xinyi Li, Zhenhao Shi, Juliana Byanyima, Peter T. Morgan, Jan-Willem van der Veen, Rui Zhang, Erin Deneke, Gene-Jack Wang, Nora D. Volkow, Corinde E. Wiers
Publikováno v:
Drug and Alcohol Dependence Reports, Vol 5, Iss , Pp 100092- (2022)
ABSTRACT: Background: We previously showed that ketogenic diet (KD) was effective in curbing alcohol withdrawal and craving in individuals with alcohol use disorder (AUD). We hypothesized that the clinical benefits were due to improvements in sleep.
Externí odkaz:
https://doaj.org/article/3700f148db254dc48eed6d6cfe69a082
Publikováno v:
Brain Sciences, Vol 13, Iss 10, p 1480 (2023)
Combined antiretroviral therapy (cART) has greatly reduced the severity of HIV-associated neurocognitive disorders in people living with HIV (PLWH); however, PLWH are more likely than the general population to use drugs and suffer from substance use
Externí odkaz:
https://doaj.org/article/bc65544d848e4166a5797cfd8ffa3287