Zobrazeno 1 - 10 of 386 pro vyhledávání: '"Gendron FP"'
1
Akademický článek
The expression of P2Y 6 receptor promotes the quality of mucus in colitic mice.
Autor: Placet M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada., Molle CM; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada., Arguin G; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada., Geha S; Department of Pathology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada.; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, QC, Canada.
Publikováno v: The FEBS journal [FEBS J] 2021 Sep; Vol. 288 (18), pp. 5459-5473. Date of Electronic Publication: 2021 Mar 25.
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2
Akademický článek
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y 6 receptor.
Autor: Girard M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Canada., Bellefeuille SD; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Eiselt É; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Canada., Arguin G; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Longpré JM; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Canada., Sarret P; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Canada; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Canada., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Canada. Electronic address: fernand-p.gendron@usherbrooke.ca.
Publikováno v: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2023 Jun; Vol. 1870 (5), pp. 119476. Date of Electronic Publication: 2023 Apr 12.
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3
Akademický článek
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
Autor: Sohail M; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Shkreta L; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Toutant J; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Rabea S; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada., Babeu JP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Huard C; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada., Coulombe-Huntington J; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada., Delannoy A; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Placet M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Geha S; Department of Pathology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, QC, Canada., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Boudreau F; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada., Tyers M; Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada., Grierson DS; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada., Chabot B; Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke. Sherbrooke, Quebec, Canada.
Publikováno v: NAR cancer [NAR Cancer] 2021 May 25; Vol. 3 (2), pp. zcab019. Date of Electronic Publication: 2021 May 25 (Print Publication: 2021).
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4
Akademický článek
Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity.
Autor: Dai, Quanhui1,2 (AUTHOR), Preusse, Kristina2 (AUTHOR), Yu, Danni1 (AUTHOR), Kovall, Rhett A.3 (AUTHOR), Thorner, Konrad2 (AUTHOR), Lin, Xinhua1 (AUTHOR) xlin@fudan.edu.cn, Kopan, Raphael2 (AUTHOR) Rafi.kopan@gmail.com
Publikováno v: PLoS Genetics. 12/12/2024, Vol. 20 Issue 12, p1-27. 27p.
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5
Akademický článek
Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor.
Autor: Bergamin LS; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy., Penolazzi L; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy., Lambertini E; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy., Falzoni S; Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Sarti AC; Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Molle CM; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., De Bonis P; Department of Neurosurgery, S. Anna University Hospital, Ferrara, Italy., Di Virgilio F; Department of Medical Sciences, University of Ferrara, Ferrara, Italy., Piva R; Department of Biomedical and Specialty Surgical Sciences, University of Ferrara, Ferrara, Italy.
Publikováno v: Journal of cellular physiology [J Cell Physiol] 2021 Jan; Vol. 236 (1), pp. 641-652. Date of Electronic Publication: 2020 Jun 24.
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6
Akademický článek
The P2Y 6 receptor signals through Gα q /Ca 2+ /PKCα and Gα 13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Autor: Girard M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Dagenais Bellefeuille S; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Eiselt É; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Brouillette R; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Placet M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Arguin G; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Longpré JM; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Sarret P; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.; Institut de Pharmacologie de Sherbrooke, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.
Publikováno v: Journal of cellular physiology [J Cell Physiol] 2020 Dec; Vol. 235 (12), pp. 9676-9690. Date of Electronic Publication: 2020 May 18.
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7
Akademický článek
The expression of the P2Y 6 receptor is regulated at the transcriptional level by p53.
Autor: Molle CM; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: caroline.molle@usherbrooke.ca., Arguin G; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: guillaume.arguin@usherbrooke.ca., Jemfer C; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: c.jemfer@hubebi.com., Placet M; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: morgane.placet@usherbrooke.ca., Dagenais Bellefeuille S; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: steve.dagenais.bellefeuille@usherbrooke.ca., Gendron FP; Department of Immunology and Cell Biology, Faculty of Medicine and Health Sciences, Pavillon of Applied Research on Cancer, Université de Sherbrooke, Sherbrooke, QC, J1E 4K8, Canada. Electronic address: fernand-p.gendron@usherbrooke.ca.
Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2020 Apr 16; Vol. 524 (4), pp. 798-802. Date of Electronic Publication: 2020 Feb 06.
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8
Akademický článek
Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.
Autor: Nassir M; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900, Israel., Pelletier J; Centre de Recherche du CHU de Québec - Université Laval, Pavillon CHUL, Québec city, QC, Canada., Arad U; Department of Rheumatology, Tel Aviv Medical Center and the Faculty of Medicine, Tel Aviv University, Tel Aviv, 6997801, Israel., Arguin G; Département d'immunologie et de biologie cellulaire, Faculté de Médecine et des sciences de la santé, Université de Sherbrooke, PRAC, 3201, Jean-Mignault, Sherbrooke, QC, J1E 4K8, Canada., Khazanov N; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900, Israel., Gendron FP; Département d'immunologie et de biologie cellulaire, Faculté de Médecine et des sciences de la santé, Université de Sherbrooke, PRAC, 3201, Jean-Mignault, Sherbrooke, QC, J1E 4K8, Canada., Sévigny J; Centre de Recherche du CHU de Québec - Université Laval, Pavillon CHUL, Québec city, QC, Canada; Département de Microbiologie-Infectiologie et d'Immunologie, Faculté de Médecine, Université Laval, Quebec city, QC G1V 4G2, Canada., Senderowitz H; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900, Israel., Fischer B; Department of Chemistry, Bar-Ilan University, Ramat-Gan, 52900, Israel. Electronic address: bilha.fischer@biu.ac.il.
Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2019 Dec 15; Vol. 184, pp. 111754. Date of Electronic Publication: 2019 Oct 04.
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9
Akademický článek
Reviewing the role of P2Y receptors in specific gastrointestinal cancers.
Autor: Bellefeuille SD; Département d'anatomie et de biologie cellulaire, Faculté de médecine et des sciences de la santé, Pavillon de recherche appliquée sur le cancer, Université de Sherbrooke, 3201 rue Jean-Mignault, Sherbrooke, Québec, J1E 4K8, Canada., Molle CM; Département d'anatomie et de biologie cellulaire, Faculté de médecine et des sciences de la santé, Pavillon de recherche appliquée sur le cancer, Université de Sherbrooke, 3201 rue Jean-Mignault, Sherbrooke, Québec, J1E 4K8, Canada., Gendron FP; Département d'anatomie et de biologie cellulaire, Faculté de médecine et des sciences de la santé, Pavillon de recherche appliquée sur le cancer, Université de Sherbrooke, 3201 rue Jean-Mignault, Sherbrooke, Québec, J1E 4K8, Canada. fernand-p.gendron@usherbrooke.ca.
Publikováno v: Purinergic signalling [Purinergic Signal] 2019 Dec; Vol. 15 (4), pp. 451-463. Date of Electronic Publication: 2019 Sep 02.
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10
Akademický článek
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-P α,α -Dithiophosphate Analogues.
Autor: Zelikman V; Department of Chemistry , Bar-Ilan University , Ramat-Gan 5290002 , Israel., Pelletier J; Centre de Recherche du CHU de Québec, Université Laval , Québec , QC , Canada., Simhaev L; Department of Chemistry , Bar-Ilan University , Ramat-Gan 5290002 , Israel., Sela A; Department of Chemistry , Bar-Ilan University , Ramat-Gan 5290002 , Israel., Gendron FP; Department of Anatomy and Cellular Biology , Université de Sherbrooke , 3201 Rue Jean-Mignault , Sherbrooke , QC J1E 4K8 , Canada., Arguin G; Department of Anatomy and Cellular Biology , Université de Sherbrooke , 3201 Rue Jean-Mignault , Sherbrooke , QC J1E 4K8 , Canada., Senderowitz H; Department of Chemistry , Bar-Ilan University , Ramat-Gan 5290002 , Israel., Sévigny J; Centre de Recherche du CHU de Québec, Université Laval , Québec , QC , Canada.; Département de Microbiologie-Infectiologie et d'Immunologie, Faculté de Médecine , Université Laval , Pavillon CHUL, 2705 Boulevard Laurier, Local T1-49 , Québec , QC G1V 4G2 , Canada., Fischer B; Department of Chemistry , Bar-Ilan University , Ramat-Gan 5290002 , Israel.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 May 10; Vol. 61 (9), pp. 3939-3951. Date of Electronic Publication: 2018 May 02.
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