Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gencer Sancar"'
Autor:
Leontine Sandforth, Sebastian Brachs, Julia Reinke, Diana Willmes, Gencer Sancar, Judith Seigner, David Juarez-Lopez, Arvid Sandforth, Jeffrey D. McBride, Jian-Xing Ma, Sven Haufe, Jens Jordan, Andreas L. Birkenfeld
Publikováno v:
Molecular Metabolism, Vol 82, Iss , Pp 101905- (2024)
Objective: Kallistatin (KST), also known as SERPIN A4, is a circulating, broadly acting human plasma protein with pleiotropic properties. Clinical studies in humans revealed reduced KST levels in obesity. The exact role of KST in glucose and energy h
Externí odkaz:
https://doaj.org/article/8029e4df1a684f388440b641e51135c4
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0001de3b0c3b4843a46dcab9512dbefb
Publikováno v:
Bio-Protocol, Vol 6, Iss 11 (2016)
Digestion of chromatin by micrococcal nuclease MNase followed by high throughput sequencing allows us to determine the location and occupancy of nucleosomes on the genome. Here in this protocol we have described optimized conditions of MNase digestio
Externí odkaz:
https://doaj.org/article/fa2b181aafd94c36a1cac104cf67246a
Autor:
Cigdem Sancar, Nati Ha, Rüstem Yilmaz, Rafael Tesorero, Tamas Fisher, Michael Brunner, Gencer Sancar
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005105 (2015)
Light is an important environmental cue that affects physiology and development of Neurospora crassa. The light-sensing transcription factor (TF) WCC, which consists of the GATA-family TFs WC1 and WC2, is required for light-dependent transcription. S
Externí odkaz:
https://doaj.org/article/d9634c31dab949ac8eb16ed484f1a59e
Autor:
Carmen Ruger-Herreros, María del Mar Gil-Sánchez, Gencer Sancar, Michael Brunner, Luis M Corrochano
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95069 (2014)
The activation of transcription by light in the fungus Neurospora crassa requires the White Collar Complex (WCC), a photoreceptor and transcription factor complex. After light reception two WCCs interact and bind the promoters of light-regulated gene
Externí odkaz:
https://doaj.org/article/20d119cb39c741f79e6bd1ee7a64dc05
Publikováno v:
Nat Metab
While fibroblast growth factor (FGF) 1 is expressed in multiple tissues, only adipose-derived and brain FGF1 have been implicated in the regulation of metabolism. Adipose FGF1 production is upregulated in response to dietary stress and is essential f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc51832070f1f3ce768ce8cd3d74806
https://doi.org/10.1038/s42255-022-00580-2
https://doi.org/10.1038/s42255-022-00580-2
Autor:
Sonja N. Brun, Gencer Sancar, Jan Lumibao, Allison S. Limpert, Huiyu Ren, Angela Ianniciello, Herve Tiriac, Michael Downes, Danielle D. Engle, Ronald M. Evans, Nicholas D.P. Cosford, Reuben J. Shaw
Amongst cancer subtypes, pancreatic ductal adenocarcinoma (PDA) has been demonstrated to be most sensitive to autophagy inhibition, which may be due to unique metabolic rewiring in these cells. The serine/threonine kinase ULK1 forms the catalytic cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9cd979bb7e86417dcc2356901a2c92
https://doi.org/10.1101/2021.05.15.444304
https://doi.org/10.1101/2021.05.15.444304
Autor:
Gencer Sancar, Sihao Liu, Emanuel Gasser, Jacqueline G. Alvarez, Christopher Moutos, Kyeongkyu Kim, Tim van Zutphen, Yuhao Wang, Timothy F. Huddy, Brittany Ross, Yang Dai, David Zepeda, Brett Collins, Emma Tilley, Matthew J. Kolar, Ruth T. Yu, Annette R. Atkins, Theo H. van Dijk, Alan Saghatelian, Johan W. Jonker, Michael Downes, Ronald M. Evans
Publikováno v:
Cell Metab
Cell metabolism, 34(1), 171-183.E6. CELL PRESS
Cell metabolism, 34(1), 171-183.E6. CELL PRESS
Inexorable increases in insulin resistance, lipolysis, and hepatic glucose production (HGP) are hallmarks of type 2 diabetes. Previously, we showed that peripheral delivery of exogenous fibroblast growth factor 1 (FGF1) has robust anti-diabetic effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830a4346330bd93206e8219bfa472963
https://hdl.handle.net/11370/b5fac37b-87e5-4748-a768-58576879b579
https://hdl.handle.net/11370/b5fac37b-87e5-4748-a768-58576879b579
Autor:
Hanspeter Herzel, Cigdem Sancar, Robert Lehmann, Michael Brunner, Gencer Sancar, Bharath Ananthasubramaniam
Publikováno v:
Information-and Communication Theory in Molecular Biology ISBN: 9783319547282
Eukaryotic genes are typically regulated by multiple transcription factors in a combinatorial manner. Quantitative understanding of gene regulation is particularly relevant for oscillatory expression due to transcriptional feedback loops. For periodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f00f632f1c080a3e34c218735191fff
https://doi.org/10.1007/978-3-319-54729-9_8
https://doi.org/10.1007/978-3-319-54729-9_8
Autor:
Michael Brunner, Gencer Sancar
Publikováno v:
Cellular and Molecular Life Sciences. 71:2667-2680
Circadian clocks orchestrate behavioral and physiological processes in a time-of-day dependent manner. The network of clock-controlled genes is intimately interconnected with metabolic regulatory circuits. Circadian clocks rhythmically regulate the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c9eed3babf57d7ec51067cc8fd876e
https://doi.org/10.1007/s00018-014-1574-7
https://doi.org/10.1007/s00018-014-1574-7