Reduction of the inflammatory responses against alginate-poly-L-lysine microcapsules by anti-biofouling surfaces of PEG-b-PLL diblock copolymers.

Autor: Milica Spasojevic, Genaro A Paredes-Juarez, Joop Vorenkamp, Bart J de Haan, Arend Jan Schouten, Paul de Vos

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e109837 (2014)

Large-scale application of alginate-poly-L-lysine (alginate-PLL) capsules used for microencapsulation of living cells is hampered by varying degrees of success, caused by tissue responses against the capsules in the host. A major cause is proinflamma

Externí odkaz: https://doaj.org/article/aae34419431544d198ccc78580a5737b

Magnetic Manipulation of Blood Conductivity with Superparamagnetic Iron Oxide-Loaded Erythrocytes

Autor: Bernhard Gleich, Genaro A Paredes-Juarez, Gavin R Philips, Antonella Antonelli, Mauro Magnani, Jeff W.M. Bulte

Publikováno v: ACS Applied Materials & Interfaces. 11:11194-11201

The active and passive electrophysiological properties of blood and tissue have been utilized in a vast array of clinical techniques to noninvasively characterize anatomy and physiology and to diagnose a wide variety of pathologies. However, the accu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f71f1acef05705c22470ba1b193d142
https://doi.org/10.1021/acsami.9b00394

Magnetically Aligned Nanorods in Alginate Capsules (MANiACs): Soft Matter Tumbling Robots for Manipulation and Drug Delivery

Autor: Sagar Chowdhury, J. Watson-Daniels, Chenghao Bi, Sahar Jafari, Olivia Hale, Shailesh B. Raval, Danica Sun, Dian R. Arifin, Benjamin A. Evans, Maria Guix, James Baker-McKee, Jeff W.M. Bulte, Bradley English, Chad Ropp, Lamar O. Mair, Pavel Stepanov, Benjamin V. Johnson, Genaro A. Paredes-Juarez, Irving N. Weinberg, Zachary Baker, David J. Cappelleri

Publikováno v: Micromachines
Volume 10
Issue 4
Micromachines, Vol 10, Iss 4, p 230 (2019)

Soft, untethered microrobots composed of biocompatible materials for completing micromanipulation and drug delivery tasks in lab-on-a-chip and medical scenarios are currently being developed. Alginate holds significant potential in medical microrobot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0b7d361829c7013756e7524e5c30bf
https://pubmed.ncbi.nlm.nih.gov/30935105

The role of pathogen-associated molecular patterns in inflammatory responses against alginate based microcapsules

Autor: Marijke M. Faas, Paul de Vos, Bart J. de Haan, Genaro A. Paredes-Juarez

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society, 172(3), 983-992. Elsevier Bedrijfsinformatie b.v.

Alginate-based microcapsules are used for immunoisolation of cells to release therapeutics on a minute-to-minute basis. Unfortunately, alginate-based microcapsules are suffering from varying degrees of success, which is usually attributed to differen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f009b4dbcd03ef69ec0ef0b55e6706ac
https://doi.org/10.1016/j.jconrel.2013.09.009

Selection of polymers for application in scaffolds applicable for human pancreatic islet transplantation

Autor: Aart A. van Apeldoorn, Paul de Vos, Marijke M. Faas, Jeroen Kuipers, Genaro A. Paredes-Juarez, Alexandra M. Smink, Anouk H G Wolters, Bart J. de Haan, Eelco J.P. de Koning, Leendert Schwab, Marten A. Engelse, Ben N G Giepmans

Publikováno v: Biomedical Materials (Bristol, England), 11(3):035006. IOP PUBLISHING LTD
Biomedical materials (Bristol, England), 11(3). IOP Publishing Ltd.
Biomedical Materials, 11(3). IOP PUBLISHING LTD

The liver is currently the site for transplantation of islets in humans. This is not optimal for islets, but alternative sites in humans are not available. Polymeric scaffolds in surgically accessible areas are a solution. As human donors are rare, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a11329155cf645314f31a8492d035f
https://hdl.handle.net/1887/99356