Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Gen Wei"'
Autor:
Xifeng Wang, Huayu Yang, Dengcheng Zhan, Haiying Sun, Qiang Huang, Yiping Zhang, Yue Lin, Gen Wei, Fuzhou Hua, Li Liu, Shibiao Chen
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39013- (2024)
Alzheimer's disease (AD) is a gradual neurodegenerative ailment that lacks any disease-modifying intervention. Our objective was to pinpoint pharmacological targets with a focus on amyloid beta (Aβ) and tau to treat and prevent AD in the European po
Externí odkaz:
https://doaj.org/article/9488e6e5b7a341a0aa37c90642243c67
Autor:
Guangyong Zhang, Qing Yao, Chubing Long, Pengcheng Yi, Jiali Song, Luojia Wu, Wei Wan, Xiuqin Rao, Yue Lin, Gen Wei, Jun Ying, Fuzhou Hua
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 3, Pp 779-793 (2025)
Mononuclear macrophage infiltration in the central nervous system is a prominent feature of neuroinflammation. Recent studies on the pathogenesis and progression of multiple sclerosis have highlighted the multiple roles of mononuclear macrophages in
Externí odkaz:
https://doaj.org/article/1c802f09ceca453b841bbc661f8e8840
Autor:
Luojia Wu, Yue Lin, Jiali Song, Longshan Li, Xiuqin Rao, Wei Wan, Gen Wei, Fuzhou Hua, Jun Ying
Publikováno v:
Neurobiology of Disease, Vol 185, Iss , Pp 106244- (2023)
Lysosomes are acidic intracellular organelles with autophagic functions that are critical for protein degradation and mitochondrial homeostasis, while abnormalities in lysosomal physiological functions are closely associated with neurological disorde
Externí odkaz:
https://doaj.org/article/86e6f71ae8f34613b69bf2fe64ffc36e
Autor:
Lieliang Zhang, Xifeng Wang, Wen Yu, Jun Ying, Pu Fang, Qingcui Zheng, Xiaojin Feng, Jialing Hu, Fan Xiao, Shoulin Chen, Gen Wei, Yue Lin, Xing Liu, Danying Yang, Yang Fang, Guohai Xu, Fuzhou Hua
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Evidence suggests that the accumulation of lipid drots (LDs) accelerates damage to mitochondria and increases the release of inflammatory factors. These have been implicated as a mechanism underlying neurodegenerative diseases or tumors and aging-rel
Externí odkaz:
https://doaj.org/article/74d38dd4b29649be9caa9643a5e26246
Autor:
Miaomiao Chen, Xingning Lai, Xifeng Wang, Jun Ying, Lieliang Zhang, Bin Zhou, Xing Liu, Jing Zhang, Gen Wei, Fuzhou Hua
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Microglia and astrocytes maintain tissue homeostasis in the nervous system. Both microglia and astrocytes have pro-inflammatory phenotype and anti-inflammatory phenotype. Activated microglia and activated astrocytes can contribute to several neurolog
Externí odkaz:
https://doaj.org/article/a2811e0270dd4a09ac0734ee067a86d5
Autor:
Yang Fang, Xifeng Wang, Danying Yang, Yimei Lu, Gen Wei, Wen Yu, Xing Liu, Qingcui Zheng, Jun Ying, Fuzhou Hua
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The intracellular energy state will alter under the influence of physiological or pathological stimuli. In response to this change, cells usually mobilize various molecules and their mechanisms to promote the stability of the intracellular energy sta
Externí odkaz:
https://doaj.org/article/05e539612c32470291abf50c8c8f845c
Autor:
Lieliang Zhang, Fan Xiao, Jing Zhang, Xifeng Wang, Jun Ying, Gen Wei, Shoulin Chen, Xiangfei Huang, Wen Yu, Xing Liu, Qingcui Zheng, Guohai Xu, Shuchun Yu, Fuzhou Hua
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Surgery and anesthesia-induced perioperative neurocognitive disorder (PND) are closely related to NOD-like receptors (NLR) family, pyrin domain containing 3 (NLRP3) inflammasome microglia inflammatory response. Inhibiting the occurrence o
Externí odkaz:
https://doaj.org/article/cb5f21d528e348b48deab027cce48ef5
Publikováno v:
In Engineering Structures 1 May 2023 282
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