Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Gen Kurosawa"'
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 6, p e1005501 (2017)
Most biological processes accelerate with temperature, for example cell division. In contrast, the circadian rhythm period is robust to temperature fluctuation, termed temperature compensation. Temperature compensation is peculiar because a system-le
Externí odkaz:
https://doaj.org/article/e8c33782832e4c7eb22ea0572547bb95
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48892 (2012)
In the mammalian brain, the suprachiasmatic nucleus (SCN) of the anterior hypothalamus is considered to be the principal circadian pacemaker, keeping the rhythm of most physiological and behavioral processes on the basis of light/dark cycles. Because
Externí odkaz:
https://doaj.org/article/ce160137dfe54c17bd55b03ec807862a
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20880 (2011)
Periods of biological clocks are close to but often different from the rotation period of the earth. Thus, the clocks of organisms must be adjusted to synchronize with day-night cycles. The primary signal that adjusts the clocks is light. In Neurospo
Externí odkaz:
https://doaj.org/article/d905b7eab139457badc82802447c42f2
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18663 (2011)
In mammals, cellular circadian rhythms are generated by a transcriptional-translational autoregulatory network that consists of clock genes that encode transcriptional regulators. Of these clock genes, Period1 (Per1) and Period2 (Per2) are essential
Externí odkaz:
https://doaj.org/article/c4c54ac29f5d4f35adea470721ec8af2
Mammalian hibernators decrease basal metabolism and body temperature (Tb) to minimize energy expenditure in harsh seasons. During hibernation, Tb drops to low temperature (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f6a5468cd2e805dd3a88e5cbaefeb54
https://doi.org/10.1101/2021.11.12.468369
https://doi.org/10.1101/2021.11.12.468369
Autor:
Motomu Endo, Kazuhiko Kume, Naohiro Kon, Yoshitaka Fukada, Hsin Tzu Wang, Yoshiaki S. Kato, Koji Kawasaki, Hideaki Tagashira, Gen Kurosawa, Yasunori Sugiyama, Ryosuke Enoki, Tatsuto Nakane, Hideo Iwasaki, Takahiro Iwamoto, Naohiro Kawamoto, Kyouhei Uemoto
Publikováno v:
Science Advances. 7
Circadian rhythms are based on biochemical oscillations generated by clock genes/proteins, which independently evolved in animals, fungi, plants, and cyanobacteria. Temperature compensation of the oscillation speed is a common feature of the circadia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864bedd9171de38c56ceee8060cdd65d
https://doi.org/10.1126/sciadv.abe8132
https://doi.org/10.1126/sciadv.abe8132
Autor:
Gen Kurosawa, Shingo Gibo
Publikováno v:
Journal of Theoretical Biology. 490:110140
Messenger RNAs are often destabilized by methylation, suggesting that mRNA methylation alters mRNA and protein dynamics. This may indicate that the gene regulatory system is reflected by the metabolic system through mRNA methylation because methylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a0014e4105960c7a392c8aca361eaf
https://doi.org/10.1016/j.jtbi.2019.110140
https://doi.org/10.1016/j.jtbi.2019.110140
Autor:
Jean-Michel Fustin, David M. Virshup, Shiqi Ye, Rajesh Narasimamurthy, Hsin Yi Chang, Masahito Ikawa, Hitoshi Okamura, Asami Oji, Bowen Zhuang, Gen Kurosawa, Kakeru Itoh, Ichiro Manabe, Rika Kojima, Masao Doi, Yasushi Ishihama, Shingo Gibo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(27)
The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a3abcaa3a7921ffca68cd92f2a1ccb
https://pubmed.ncbi.nlm.nih.gov/29784786
https://pubmed.ncbi.nlm.nih.gov/29784786
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
MicroRNAs (miRNAs) are small, non-coding RNAs that play critical roles in the post-transcriptional regulation of gene expression. Although the molecular mechanisms of the biogenesis and activation of miRNA have been extensively studied, the details o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4752d839f13de1094e4ecfb78aa602a
https://pubmed.ncbi.nlm.nih.gov/28974737
https://pubmed.ncbi.nlm.nih.gov/28974737
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 13, Iss 6, p e1005501 (2017)
PLoS Computational Biology, Vol 13, Iss 6, p e1005501 (2017)
Most biological processes accelerate with temperature, for example cell division. In contrast, the circadian rhythm period is robust to temperature fluctuation, termed temperature compensation. Temperature compensation is peculiar because a system-le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e76b8e7fbbc00b97c5dfb90b63f1b9
https://pubmed.ncbi.nlm.nih.gov/28594845
https://pubmed.ncbi.nlm.nih.gov/28594845