Výsledky vyhledávání - "Gemma Regan-Mochrie"

Balancing act of a leading strand DNA polymerase-specific domain and its exonuclease domain promotes genome-wide sister replication fork symmetry

Autor: Xiangzhou Meng, Clémence Claussin, Gemma Regan-Mochrie, Iestyn Whitehouse, Xiaolan Zhao

Publikováno v: Genes & Development. 37:74-79

Pol2 is the leading-strand DNA polymerase in budding yeast. Here we describe an antagonism between its conserved POPS (Pol2 family-specific catalytic core peripheral subdomain) and exonuclease domain and the importance of this antagonism in genome re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebdb25431a36dff51eeaebdc32a5e827
https://doi.org/10.1101/gad.350054.122

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Yeast ORC sumoylation status fine-tunes origin licensing

Autor: Gemma Regan-Mochrie, Timothy Hoggard, Nikhil Bhagwat, Gerard Lynch, Neil Hunter, Dirk Remus, Catherine A. Fox, Xiaolan Zhao

Publikováno v: Genes & development, vol 36, iss 13-14

Sumoylation is emerging as a posttranslation modification important for regulating chromosome duplication and stability. The origin recognition complex (ORC) that directs DNA replication initiation by loading the MCM replicative helicase onto origins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4575383268c7297c6f136c2282898c
https://pubmed.ncbi.nlm.nih.gov/35926881

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