Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gemma R. Grant"'
Autor:
Karl W. Broman, Andrew G. Smith, Bruce Clothier, Gemma R. Grant, Susan W. Robinson, David J. Judah, R.E. Edwards, Reginald Davies
Publikováno v:
Hepatology. 44:174-185
Polymorphisms of genes linked to iron metabolism may account for individual variability in hemochromatosis and iron status connected with liver and cardiovascular diseases, cancers, toxicity, and infection. Mouse strains exhibit marked differences in
Autor:
Yuri E. Dubrova, Alistair Ritchie, Celia A. May, Alec J. Jeffreys, John D.H. Stead, Angela C. Shone, Keiji Tamaki, Ruth C. Barber, Esther Signer, Caroline R. H. Hollies, Rita Neumann, Gemma R. Grant, Maria Panayi, Philippe Bois, Jérôme Buard
Publikováno v:
Electrophoresis. 20:1665-1675
Minisatellites include some of the most variable loci in the human genome and are superb for dissecting processes of tandem repeat DNA instability. Single DNA molecule analysis has revealed different mutation processes operating in the soma and germl
Publikováno v:
Genomics. 80(1)
Minisatellites provide very informative systems for analyzing processes of tandem repeat DNA turnover in humans. The mouse genome also contains authentic minisatellites, but none has yet been found to show high levels of instability. Indirect evidenc
Publikováno v:
Mutation research. 500(1-2)
Expanded simple tandem repeat (ESTR) loci include some of the most unstable DNA in the mouse genome and have been extensively used in pedigree studies of germline mutation. We now show that repeat DNA instability at the mouse ESTR locus Ms6-hm can al
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489900913
Evermore sophisticated tests are need to study germline toxicology. The gene conversion-based systems developed in Leicester and in the USA are steps in the right direction, but a lot of validation both in vivo and in vitro is required. Transgenic te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33fc066344c2d725de7a09e553d18a30
https://doi.org/10.1007/978-1-4899-0089-0_14
https://doi.org/10.1007/978-1-4899-0089-0_14
Publikováno v:
The American Journal of Human Genetics. (4):801-809
Germline mutation at eight human minisatellite loci has been studied among families from rural areas of the Kiev and Zhitomir regions of Ukraine, which were heavily contaminated by radionuclides after the Chernobyl accident. The control and exposed g
Publikováno v:
Genome Biology
Genome Biology, BioMed Central, 2007, 8, pp.R80. ⟨10.1186/gb-2007-8-5-r80⟩
Genome Biology, 2007, 8, pp.R80. ⟨10.1186/gb-2007-8-5-r80⟩
Genome Biology, BioMed Central, 2007, 8, pp.R80. ⟨10.1186/gb-2007-8-5-r80⟩
Genome Biology, 2007, 8, pp.R80. ⟨10.1186/gb-2007-8-5-r80⟩
Global analysis of four minisatellite loci in House Mouse reveals unexpected long-range gene flow between populations and subspecies.
Background Four hypervariable minisatellite loci were scored on a panel of 116 individuals of various geographi
Background Four hypervariable minisatellite loci were scored on a panel of 116 individuals of various geographi