Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gemma Pidelaserra Martí"'
Autor:
Rūta Veinalde, Gemma Pidelaserra-Martí, Coline Moulin, Lara M. Jeworowski, Linda Küther, Christian J. Buchholz, Dirk Jäger, Guy Ungerechts, Christine E. Engeland
Publikováno v:
Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 43-58 (2022)
PD-1/PD-L1 checkpoint blockade has achieved unprecedented success in cancer immunotherapy. Nevertheless, many immune-excluded tumors are resistant to therapy. Combination with oncolytic virotherapy may overcome resistance by inducing acute inflammati
Externí odkaz:
https://doaj.org/article/b0640d5bf54b4f37a29eefe3f960eb3d
Autor:
Rūta Veinalde, Gemma Pidelaserra-Martí, Coline Moulin, Chin Leng Tan, Theresa E. Schäfer, Na Kang, Claudia R. Ball, Jonas Leichsenring, Albrecht Stenzinger, Lars Kaderali, Dirk Jäger, Guy Ungerechts, Christine E. Engeland
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionPancreatic ductal adenocarcinoma (PDAC) is largely refractory to cancer immunotherapy with PD-1 immune checkpoint blockade (ICB). Oncolytic virotherapy has been shown to synergize with ICB. In this work, we investigated the combination of
Externí odkaz:
https://doaj.org/article/ba74acb47dae49da8309a7f9f1784388
Autor:
Elena Busch, Kristina D. Kubon, Johanna K. M. Mayer, Gemma Pidelaserra-Martí, Jessica Albert, Birgit Hoyler, Johannes P. W. Heidbuechel, Kyle B. Stephenson, Brian D. Lichty, Wolfram Osen, Stefan B. Eichmüller, Dirk Jäger, Guy Ungerechts, Christine E. Engeland
Publikováno v:
Viruses, Vol 12, Iss 2, p 242 (2020)
Priming and activation of CD8+ T cell responses is crucial to achieve anti-viral and anti-tumor immunity. Live attenuated measles vaccine strains have been used successfully for immunization for decades and are currently investigated in trials of onc
Externí odkaz:
https://doaj.org/article/9af18000f98945f6b2fe4a914b25707b
Publikováno v:
Cytokine & Growth Factor Reviews. 56:28-38
The study of measles virus (MeV) as a cancer immunotherapeutic was prompted by clinical observations of leukemia and lymphoma regressions in patients following measles virus infection in the 1970s and 1980s. Since then, numerous preclinical studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa8edef743d683feef711533c4f6cae
https://doi.org/10.1016/j.cytogfr.2020.07.009
https://doi.org/10.1016/j.cytogfr.2020.07.009
Autor:
Christine E. Engeland, Linda Küther, Guy Ungerechts, Christian J. Buchholz, Dirk Jäger, Rūta Veinalde, Gemma Pidelaserra-Martí, Lara Maria Jeworowski, Coline Moulin
Publikováno v:
Molecular therapy, 24:43-58
Molecular Therapy: Oncolytics, Vol 24, Iss, Pp 43-58 (2022)
Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 24, Iss, Pp 43-58 (2022)
Molecular Therapy Oncolytics
PD-1/PD-L1 checkpoint blockade has achieved unprecedented success in cancer immunotherapy. Nevertheless, many immune-excluded tumors are resistant to therapy. Combination with oncolytic virotherapy may overcome resistance by inducing acute inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e1f578f8f2b8a4e8d42ee9932982390
https://repository.publisso.de/resource/frl:6431729
https://repository.publisso.de/resource/frl:6431729
Autor:
Gemma Pidelaserra Martí, G. Triller, Christian E. Busse, Hedda Wardemann, Thomas Höfer, Lisa Buchauer, Stephen L. Hoffman, Sumana Chakravarty, Elena A. Levashina, Rajagopal Murugan, Peter G. Kremsner, Katharina Imkeller, Giulia Costa, B. Kim Lee Sim, Benjamin Mordmüller, Cornelia Kreschel
Publikováno v:
Science Immunology
Affinity maturation, the clonal selection and expansion of antigen-activated B cells expressing somatically mutated antibody variants that develop during T cell-dependent germinal center reactions, is considered pivotal for efficient development of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50085e624d3d80307c2e907d62906181
https://doi.org/10.1126/sciimmunol.aap8029
https://doi.org/10.1126/sciimmunol.aap8029
Autor:
Hedda Wardemann, A. Bosch, S.W. Scally, Giulia Costa, Peter G. Kremsner, Hassan Jumaa, Benjamin Mordmüller, G. Triller, B. Kim Lee Sim, Rajagopal Murugan, Valerio Renna, Stephen L. Hoffman, Katharina Imkeller, Jean-Philippe Julien, Gemma Pidelaserra Martí, Elena A. Levashina
Publikováno v:
Science
Surface antibody maturation Affinity maturation in B cells generates antibodies with increasingly enhanced antigen-binding properties. Imkeller et al. investigated the maturation of human B cells that express protective antibodies against the circums
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9515e66b24f1f4570d4baad81b83d7a3