Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gemma Mudd"'
Autor:
Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Kevin McDonnell, Philip Brandish, Nicholas Keen, Phil Jeffrey
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/6414f70ad96342768354adee2801717c
Autor:
Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen, Rachel Dods, Rachid Lani, Katerine Van Rietschoten, Tom Stephen, Fanglei You
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background In contrast to immune checkpoint inhibitors, the use of antibodies as agonists of immune costimulatory receptors as cancer therapeutics has largely failed. We sought to address this problem using a new class of modular synthetic drugs, ter
Externí odkaz:
https://doaj.org/article/2beebb8f72534439867cc69dff340982
Autor:
Jun Ma, Sailaja Battula, Kristen Hurov, Johanna lahdenranta, Gemma Mudd, Punit Upadhyaya, Elizabeth Repash, Julia Kristensson, Marianna Kleyman, Jessica Kublin, Liuhong Chen, Eric Haines, Kevin McDonnell, Philip Brandish, Nicholas Keen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/6541410690f84d4cbbca57e8c0959953
Supplementary Figures 1-3 and Tables 1-6 from MMAE Delivery Using the Bicycle Toxin Conjugate BT5528
Autor:
Nicholas Keen, Johanna Lahdenranta, Sophie Watcham, Liuhong Chen, Silvia Pavan, Katerine Van Rietschoten, Philip Huxley, Gemma Mudd, Amy Brown, Gavin Bennett
Supplementary data are provided to further understand the pharmacokinetics and efficacy of BT5528 and EphA2 expression in tumors. Figure S1: Plasma concentration-time curves of BT5528 and MMAE following IV dosing of BT5528 1 in mouse, rat, and cynomo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d028f22c98c3c31042280fe8a7a22e41
https://doi.org/10.1158/1535-7163.22521787.v1
https://doi.org/10.1158/1535-7163.22521787.v1
Autor:
Nicholas Keen, Johanna Lahdenranta, Sophie Watcham, Liuhong Chen, Silvia Pavan, Katerine Van Rietschoten, Philip Huxley, Gemma Mudd, Amy Brown, Gavin Bennett
Supplementary information detailing methods used to generate in vitro and in vivo data presented in paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28102bfe9e7011fdffae4da9f9ba601f
https://doi.org/10.1158/1535-7163.22521784.v1
https://doi.org/10.1158/1535-7163.22521784.v1
Autor:
Richard Gorlick, Edward A. Kolb, Malcolm A. Smith, Peter J. Houghton, Raushan T. Kurmasheva, Gemma Mudd, Johanna Lahdenranta, Philip Huxley, Tara Gelb, Stephen W. Erickson, Eric J. Earley, Alexander J. Lazar, Jing Wang, Sankaranarayanan Kannan, Sylvester Jusu, Zhaohui Xu, Douglas J. Harrison, Jonathan D. Gill, Michael E. Roth, Pooja Hingorani, Rossana Lazcano, Zhongting Zhang, Wendong Zhang, Xiangjun Tian, Yifei Wang
Immunoconjugates targeting cell-surface antigens have demonstrated clinical activity to enable regulatory approval in several solid and hematologic malignancies. We hypothesize that a rigorous and comprehensive surfaceome profiling approach to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7ea80bc4b8e698adfe074c0396aa17
https://doi.org/10.1158/1535-7163.c.6543420.v1
https://doi.org/10.1158/1535-7163.c.6543420.v1
Autor:
Richard Gorlick, Edward A. Kolb, Malcolm A. Smith, Peter J. Houghton, Raushan T. Kurmasheva, Gemma Mudd, Johanna Lahdenranta, Philip Huxley, Tara Gelb, Stephen W. Erickson, Eric J. Earley, Alexander J. Lazar, Jing Wang, Sankaranarayanan Kannan, Sylvester Jusu, Zhaohui Xu, Douglas J. Harrison, Jonathan D. Gill, Michael E. Roth, Pooja Hingorani, Rossana Lazcano, Zhongting Zhang, Wendong Zhang, Xiangjun Tian, Yifei Wang
Supplementary Figure from Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b112014e6ad507d3fbb602485a955b34
https://doi.org/10.1158/1535-7163.22522536.v1
https://doi.org/10.1158/1535-7163.22522536.v1
Autor:
Nicholas Keen, Johanna Lahdenranta, Sophie Watcham, Liuhong Chen, Silvia Pavan, Katerine Van Rietschoten, Philip Huxley, Gemma Mudd, Amy Brown, Gavin Bennett
Supplementary Chemical Structures provides an inventory and structural diagrams of all Bicycle conjugates used in paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7950b471e78d68b5160b6cf58eaf72
https://doi.org/10.1158/1535-7163.22521790
https://doi.org/10.1158/1535-7163.22521790
Autor:
Richard Gorlick, Edward A. Kolb, Malcolm A. Smith, Peter J. Houghton, Raushan T. Kurmasheva, Gemma Mudd, Johanna Lahdenranta, Philip Huxley, Tara Gelb, Stephen W. Erickson, Eric J. Earley, Alexander J. Lazar, Jing Wang, Sankaranarayanan Kannan, Sylvester Jusu, Zhaohui Xu, Douglas J. Harrison, Jonathan D. Gill, Michael E. Roth, Pooja Hingorani, Rossana Lazcano, Zhongting Zhang, Wendong Zhang, Xiangjun Tian, Yifei Wang
Supplementary Data from Comprehensive Surfaceome Profiling to Identify and Validate Novel Cell-Surface Targets in Osteosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be984949854c626083a6af42bbd0f3f
https://doi.org/10.1158/1535-7163.22522539.v1
https://doi.org/10.1158/1535-7163.22522539.v1
Autor:
Daniel P. Teufel, Klaus Kopka, Uwe Haberkorn, Karin Leotta, Ursula Schierbaum, Gemma Mudd, Gavin Bennett, Liuhong Chen, Edward H. Walker, Catherine L. Stace, Spencer Campbell, Helen Harrison, Ann-Christin Baranski, Katerine van Rietschoten, Ulrike Bauder-Wüst, Silvia Pavan, Matthias Eder
The file contains supplemental details related to sequence information of the bicyclic peptides referred to in the text, binding data, organ distribution data, PK parameters, mouse and human plasma stability, in vivo metabolism of BCY-B2 in mice, cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48e1ab702f23ec4c672dff01350427c9
https://doi.org/10.1158/0008-5472.22422660
https://doi.org/10.1158/0008-5472.22422660