Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Gemma F. Codner"'
Autor:
Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F. Codner, Marie Hutchison, Matthew Mackenzie, Michael Farmer, Thomas Coysh, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J. Cunningham, Emmanuel A. Asante, Sebastian Brandner, John Collinge, Simon Mead
Publikováno v:
Neurobiology of Disease, Vol 190, Iss , Pp 106363- (2024)
Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is thought to occur when the cellular prion protein (PrPC) spontaneously misfolds and assembles into prion fibrils, culminating in fatal neurodegeneration. In a genome-wi
Externí odkaz:
https://doaj.org/article/44274454a3b548c1acc3170aed6ccfe8
Autor:
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, Alasdair Allan, Gemma F. Codner, Remya R. Nair, Charlotte Tibbit, Ross McLeod, Zeinab Ali, Judith Noda, Alessandro Marrero-Gagliardi, José M. Brito-Armas, Muhammet M. Öztürk, Michelle Simon, Edward O’Neill, Sam Bryce-Smith, Jackie Harrison, Gemma Atkins, Silvia Corrochano, Michelle Stewart, Lydia Teboul, Abraham Acevedo-Arozena, Elizabeth M.C. Fisher, Thomas J. Cunningham
Publikováno v:
iScience, Vol 25, Iss 4, Pp 103999- (2022)
Externí odkaz:
https://doaj.org/article/b6e675c7a1d040dd9354ef6662434d04
Autor:
Anny Devoy, Georgia Price, Francesca De Giorgio, Rosie Bunton-Stasyshyn, David Thompson, Samanta Gasco, Alasdair Allan, Gemma F. Codner, Remya R. Nair, Charlotte Tibbit, Ross McLeod, Zeinab Ali, Judith Noda, Alessandro Marrero-Gagliardi, José M. Brito-Armas, Muhammet M. Öztürk, Michelle Simon, Edward O'Neill, Sam Bryce-Smith, Jackie Harrison, Gemma Atkins, Silvia Corrochano, Michelle Stewart, Lydia Teboul, Abraham Acevedo-Arozena, Elizabeth M.C. Fisher, Thomas J. Cunningham
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103463- (2021)
Summary: Amyotrophic lateral sclerosis/frontotemporal dementia (ALS/FTD) is a fatal neurodegenerative disorder, and continued innovation is needed for improved understanding and for developing therapeutics. We have created next-generation genomically
Externí odkaz:
https://doaj.org/article/5af44f859e954ddaba09b5e693fc05a6
Autor:
Gemma F. Codner, Joffrey Mianné, Adam Caulder, Jorik Loeffler, Rachel Fell, Ruairidh King, Alasdair J. Allan, Matthew Mackenzie, Fran J. Pike, Christopher V. McCabe, Skevoulla Christou, Sam Joynson, Marie Hutchison, Michelle E. Stewart, Saumya Kumar, Michelle M. Simon, Loranne Agius, Quentin M. Anstee, Kirill E. Volynski, Dimitri M. Kullmann, Sara Wells, Lydia Teboul
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract Background Recent advances in clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) genome editing have led to the use of long single-stranded DNA (lssDNA) molecules for generating conditional
Externí odkaz:
https://doaj.org/article/ee1cca96cdab4bc9a1b2e27269d0610a
Autor:
Emma Jones, Elizabeth Hill, Jacqueline Linehan, Tamsin Nazari, Adam Caulder, Gemma F Codner, Marie Hutchison, Matthew Mackenzie, Michael Wiggins De Oliveira, Huda Al-Doujaily, Malin Sandberg, Emmanuelle Viré, Thomas J Cunningham, Emmanuel A Asante, Sebastian Brandner, John Collinge, Simon Mead
Sporadic Creutzfeldt-Jakob disease (sCJD) is the most common human prion disease, which occurs when the cellular prion protein (PrPC) spontaneously misfolds into disease-associated forms, culminating in fatal neurodegeneration. In a genome-wide assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::102af94872efdcb9ae048729878b4e73
https://doi.org/10.1101/2023.01.10.523281
https://doi.org/10.1101/2023.01.10.523281
Autor:
Matthew Mackenzie, Alex Fower, Alasdair J. Allan, Gemma F. Codner, Rosie K. Bunton-Stasyshyn, Lydia Teboul
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afbfcf2311037e778782e70023dbafb4
https://doi.org/10.1007/978-1-0716-2990-1_4
https://doi.org/10.1007/978-1-0716-2990-1_4
Publikováno v:
Laboratory Animals. 56:69-82
The emergence of an array of genome-editing tools in recent years has facilitated the introduction of genetic modifications directly into the embryo, increasing the ease, efficiency and catalogue of alleles accessible to researchers across a range of
Autor:
Mark Stevenson, Gemma F. Codner, Rajesh V. Thakker, Michelle Stewart, Sara Wells, Fadil M. Hannan, Kreepa Kooblall, Asha L. Bayliss, Lydia Teboul, Victoria Stokes, Caroline M Gorvin
Publikováno v:
Human Molecular Genetics
Adaptor protein 2 (AP2), a heterotetrameric complex comprising AP2α, AP2β2, AP2μ2 and AP2σ2 subunits, is ubiquitously expressed and involved in endocytosis and trafficking of membrane proteins, such as the calcium-sensing receptor (CaSR), a G-pro
Autor:
Sherylanne Newton, Fanbo Kong, Adam J. Carlton, Carlos Aguilar, Andrew Parker, Gemma F. Codner, Lydia Teboul, Sara Wells, Steve D. M. Brown, Walter Marcotti, Michael R. Bowl
Mammalian hearing involves the mechanoelectrical transduction (MET) of sound-induced fluid waves in the cochlea. Essential to this process are the specialised sensory cochlear cells, the inner (IHCs) and outer hair cells (OHCs). While genetic hearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edee8af8ed3cebb01fa80cbc3073474e
https://eprints.whiterose.ac.uk/183662/1/journal.pgen.1009937.pdf
https://eprints.whiterose.ac.uk/183662/1/journal.pgen.1009937.pdf
Autor:
Carlos A. Aguilar, Michael R. Bowl, Adam J Carlton, Steve D.M. Brown, Sara Wells, Fanbo Kong, Lydia Teboul, Andrew Parker, Walter Marcotti, Gemma F. Codner, Sherylanne Newton
Mammalian hearing involves the mechanoelectrical transduction (MET) of sound-induced fluid waves in the cochlea. Essential to this process are the specialised sensory cochlear cells, the inner (IHCs) and outer hair cells (OHCs). While genetic hearing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c795668b4d8afabbb61948f4053eca76
https://doi.org/10.1101/2021.11.10.468016
https://doi.org/10.1101/2021.11.10.468016