Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gemma E. Mudd"'
Autor:
Heather Scott, Katie Hill, Liuhong Chen, Kevin McDonnell, Philip Brandish, Nicholas Keen, Rachel Dodds, Laura L Goodfield, Robert P Hammer, Winston Lu, Tamera Ashworth, Hannah S Gardner, Luca Mascheroni, Tazmin Martin, Matthieu Masureel, Sandra Uhlenbroich, Marta Amaral, Julia Kristenson, Gemma E Mudd
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/106eccc88ac34f02b396bec325cdea45
Autor:
Kevin Lee, Nicholas Keen, Phil Jeffrey, Michael J. Skynner, Johanna Lahdenranta, Eric Haines, Carly Campbell, Peter U. Park, Amy N. Brown, Heather S. Scott, Sophie M. Watcham, Katerine Van Rietschoten, Paul J. Beswick, Helen Harrison, Gemma E. Mudd, Liuhong Chen, Gavin Bennett, Michael Rigby
Supplementary Figure from BT8009; A Nectin-4 Targeting Bicycle Toxin Conjugate for Treatment of Solid Tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0148ec0572dcf04288b6c7ac55148911
https://doi.org/10.1158/1535-7163.22523875
https://doi.org/10.1158/1535-7163.22523875
Autor:
Gemma E. Mudd, Heather Scott, Liuhong Chen, Katerine van Rietschoten, Gabriela Ivanova-Berndt, Katarzyna Dzionek, Amy Brown, Sophie Watcham, Lewi White, Peter U. Park, Phil Jeffrey, Mike Rigby, Paul Beswick
Publikováno v:
Journal of medicinal chemistry. 65(21)
Bicycle toxin conjugates (BTCs) are a promising new class of molecules for targeted delivery of toxin payloads into tumors. Herein we describe the discovery of BT8009, a Nectin-4 targeting BTC currently under clinical evaluation. Nectin-4 is overexpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef778895f7d675a7a657e81ab8226e23
https://pubmed.ncbi.nlm.nih.gov/36204777
https://pubmed.ncbi.nlm.nih.gov/36204777
Autor:
Punit Upadhyaya, Julia Kristensson, Johanna Lahdenranta, Elizabeth Repash, Jun Ma, Jessica Kublin, Gemma E. Mudd, Lia Luus, Phil Jeffrey, Kristen Hurov, Kevin McDonnell, Nicholas Keen
Publikováno v:
Journal of medicinal chemistry. 65(14)
CD137 (4-1BB) is a co-stimulatory receptor on immune cells and Nectin-4 is a cell adhesion molecule that is overexpressed in multiple tumor types. Using a series of poly(ethylene glycol) (PEG)-based linkers, synthetic bicyclic peptides targeting CD13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c27610ba02170186a7dd0cfd287a4aa
https://pubmed.ncbi.nlm.nih.gov/35819182
https://pubmed.ncbi.nlm.nih.gov/35819182