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CD200 ectodomain shedding into the tumor microenvironment leads to NK cell dysfunction and apoptosis
Autor:
Huw J. Morgan, Elise Rees, Simone Lanfredini, Kate A. Powell, Jasmine Gore, Alex Gibbs, Charlotte Lovatt, Gemma E. Davies, Carlotta Olivero, Boris Y. Shorning, Giusy Tornillo, Alex Tonks, Richard Darley, Eddie C.Y. Wang, Girish K. Patel
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 21 (2022)
The basis of immune evasion, a hallmark of cancer, can differ even when cancers arise from one cell type such as in the human skin keratinocyte carcinomas: basal and squamous cell carcinoma. Here we showed that the basal cell carcinoma tumor–initia
Externí odkaz:
https://doaj.org/article/ea703a273eba40cda8c0b9d20462893e