Výsledky vyhledávání - "Gemma E Bone"

Clinical findings in 78 suspected cases of bovine spongiform encephalopathy in Great Britain

Autor: S. A. C. Hawkins, Timm Konold, F. Courtin, Gemma E Bone, S.J. Ryder, C. Berthelin-Baker

Publikováno v: Veterinary Record. 155:659-666

The clinical findings in 59 cows with bovine spongiform encephalopathy (BSE) were compared with those in 19 cattle that were submitted as BSE suspects but not confirmed by immunohistochemistry. Both groups were also compared with a control group of 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac2a264be913dc80813e70d6ed2e92c
https://doi.org/10.1136/vr.155.21.659

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Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges

Autor: Gemma E Bone, Saira Cawthraw, Derek Clifford, Michael J Stack, Melanie J. Chaplin, Timm Konold, Marion Simmons

Publikováno v: BMC Veterinary Research, Vol 8, Iss 1, p 22 (2012)
BMC Veterinary Research

Background The majority of atypical bovine spongiform encephalopathy (BSE) cases so far identified worldwide have been detected by active surveillance. Consequently the volume and quality of material available for detailed characterisation is very li

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80a9e9e7845eb3886d5ac20bd7c8877
https://doi.org/10.1186/1746-6148-8-22

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Time and frequency domain analysis of heart rate variability in cattle affected by bovine spongiform encephalopathy

Autor: Timm Konold, Gemma E Bone, Marion Simmons

Publikováno v: BMC Research Notes, Vol 4, Iss 1, p 259 (2011)
BMC Research Notes

Background Heart rate variability (HRV) analysis is a method to assess the function of the autonomic nervous system. Brainstem nuclei that influence HRV are affected by vacuolar changes and accumulation of disease-associated prion protein (PrPd) in b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8aff99e9e91b124bb7f2b8c6b83d6c
https://doi.org/10.1186/1756-0500-4-259

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Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

Autor: Wilfred Goldmann, Lorenzo González, S. A. C. Hawkins, Sílvia Sisó, Timm Konold, Marion Simmons, Saira Cawthraw, Gemma E Bone, Laura Phelan

Publikováno v: BMC Veterinary Research, Vol 6, Iss 1, p 13 (2010)
BMC Veterinary Research
Konold, T, Bone, G E, Phelan, L J, Simmons, M M, Gonzalez, L, Siso, S, Goldmann, W, Cawthraw, S & Hawkins, S A 2010, ' Monitoring of clinical signs in goats with transmissible spongiform encephalopathies ', BMC Veterinary Research, vol. 6, no. 13, 13 . https://doi.org/10.1186/1746-6148-6-13

BackgroundAs there is limited information about the clinical signs of BSE and scrapie in goats, studies were conducted to describe the clinical progression of scrapie and BSE in goats and to evaluate a short clinical protocol for its use in detecting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fef4a7ab1ca4cd4a12d1680106873ed
https://doi.org/10.1186/1746-6148-6-13

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Relationship between clinical signs and postmortem test status in cattle experimentally infected with the bovine spongiform encephalopathy agent

Autor: Angus Wear, Michael J Stack, Amanda Sach, A. Robin Sayers, Timm Konold, Gerald A. H. Wells, S. A. C. Hawkins, Gemma E Bone, Marion Simmons, Steven Van Winden

Publikováno v: BMC Veterinary Research
BMC Veterinary Research, Vol 6, Iss 1, p 53 (2010)

Background Various clinical protocols have been developed to aid in the clinical diagnosis of classical bovine spongiform encephalopathy (BSE), which is confirmed by postmortem examinations based on vacuolation and accumulation of disease-associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da6f77446b930af89434b7c33fa3e2c
https://pubmed.ncbi.nlm.nih.gov/21143919

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Pruritus is a common feature in sheep infected with the BSE agent

Autor: Martin Jeffrey, Christine Frédérique Berthelin-Baker, S. J. Bellworthy, Timm Konold, G. Dexter, Alberto Vidal-Diez, Marion Simmons, Melanie J. Chaplin, Andy Davis, Gemma E Bone, Peter Hill, Raül Tortosa

Publikováno v: BMC Veterinary Research, Vol 4, Iss 1, p 16 (2008)
BMC Veterinary Research

BackgroundThe variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain, br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e8509702610950e8aea7fc3c3766fa
http://www.biomedcentral.com/1746-6148/4/16

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Scrapie in goats

Autor: Gemma E Bone, S. J. Moore, G. Dexter, R. G. Pettitt, Timm Konold, Marion Simmons

Publikováno v: Veterinary Record. 161:395-396

SIR, — Following the amendment of ec regulation 999/2001, which covers rules for the prevention, control and eradication of certain transmissible spongiform encephalopathies (tses), since June 26, 2007, routine scrapie testing of female goats over

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https://doi.org/10.1136/vr.161.11.395-d

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Clinical findings in two cases of atypical scrapie in sheep: a case report

Autor: Ginny C. Saunders, Timm Konold, Gemma E Bone, Sharon Everitt, John Bracegirdle, Melanie J. Chaplin, Saira Cawthraw, Andrew Davis, Marion Simmons

Publikováno v: BMC Veterinary Research
BMC Veterinary Research, Vol 3, Iss 1, p 2 (2007)

Background Atypical scrapie is a recently recognised form of transmissible spongiform encephalopathy of sheep that differs from classical scrapie in its neuropathological and biochemical features. Most cases are detected in apparently healthy sheep a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82bb4b361f6e1cc9aa702df1b79a450
http://europepmc.org/articles/PMC1810526

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Heart rate variability analysis in sheep affected by transmissible spongiform encephalopathies

Autor: Gemma E Bone, Timm Konold

Publikováno v: BMC Research Notes
BMC Research Notes, Vol 4, Iss 1, p 539 (2011)

Background The function of the autonomic nervous system can be assessed by determining heart rate variability (HRV), which is impaired in some brainstem diseases in humans. Transmissible spongiform encephalopathies (TSEs) in sheep are diseases charac

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