Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Gemma A. J. Kuijpers"'
Autor:
Harvey B. Pollard, Gertrud Goping, Gemma A. J. Kuijpers, Moussa B.H. Youdim, Oluwadare M. Adeyemo
Publikováno v:
Experimental Neurology. 142:170-178
The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can induce a parkinsonian syndrome in humans and nonhuman primates, which is susceptible to treatment and prevention by drugs such as L-DOPA and L-deprenyl. Recently, we have reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::affc1d8d6a9a2e3fb80b3e101105e378
https://doi.org/10.1006/exnr.1996.0188
https://doi.org/10.1006/exnr.1996.0188
Publikováno v:
FEBS Letters
FEBS Letters, Wiley, 1996, 392 (3), pp.263-268. ⟨10.1016/0014-5793(96)00827-7⟩
FEBS Letters, Wiley, 1996, 392 (3), pp.263-268. ⟨10.1016/0014-5793(96)00827-7⟩
Following incubation of human fibroblasts with Ca2+ ionophore A23187, we found strong immunofluorescence labelling of the nuclear envelope by annexin IV antibody. Using confocal imaging of cells loaded with Fluo-3, we showed that A23187 generates an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456c8eefb060289137360ed42ddb740a
https://doi.org/10.1016/0014-5793(96)00827-7
https://doi.org/10.1016/0014-5793(96)00827-7
Publikováno v:
Brain Research. 687:35-52
The neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) causes a Parkinsonian syndrome in the goldfish (Carassius auratus), characterized by transient bradykinesia, the accumulation of MPP+ in the brain, and a decrease in the forebrain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7410149381f31848d13e10fd21ca7c
https://doi.org/10.1016/0006-8993(95)00391-3
https://doi.org/10.1016/0006-8993(95)00391-3
Publikováno v:
Cell & Tissue Research. 279:85-92
Adrenal medullary chromaffin cells secrete catecholamines through exocytosis of their intracellular chromaffin granules. Osmotic granule swelling has been implicated to play a role in the generation of membrane stress associated with the fusion of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed45eabe1878eed40b8ed53255e0513
https://doi.org/10.1007/bf00300694
https://doi.org/10.1007/bf00300694
Publikováno v:
British Journal of Pharmacology. 113:471-478
1. Strychnine, which is known as a potent and selective antagonist of the inhibitory glycine receptor in the central nervous system, inhibits the nicotinic stimulation of catecholamine release from bovine cultured adrenal chromaffin cells in a concen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbb5676e5972e35f4f89c1960c0cab8
https://doi.org/10.1111/j.1476-5381.1994.tb17013.x
https://doi.org/10.1111/j.1476-5381.1994.tb17013.x
Publikováno v:
Cell & Tissue Research. 269:323-330
Synexin (annexin VII) is a Ca(2+)- and phospholipid-binding protein which has been proposed to play a role in Ca(2+)-dependent membrane fusion processes. Using a monoclonal antibody against synexin, Mab 10E7, and immunogold, we carried out a semiquan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0fc2fe04e107319b0544173607ebcb
https://doi.org/10.1007/bf00319624
https://doi.org/10.1007/bf00319624
Fluorescent lipid analogue 3,3´-dioctadecyloxacarbocyanine incorporated into biological membranes was used to induce photoactivation of a hydrophobic probe 5-[125I]iodonaphthyl-1-azide (125INA) by energy transfer and to thereby confine subsequent ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1eafb4fe9543cde75326253826e303c
https://europepmc.org/articles/PMC1219821/
https://europepmc.org/articles/PMC1219821/
Publikováno v:
Biochimica et biophysica acta. 1234(2)
The effects of the protein synthesis inhibitors actinomycin D and cycloheximide on the cellular content of the calcium binding protein synexin, and on the secretory response of cultured bovine adrenal medullary chromaffin cells were determined. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de425bbe976a74651fc2c8229cd9d936
https://pubmed.ncbi.nlm.nih.gov/7696302
https://pubmed.ncbi.nlm.nih.gov/7696302
Autor:
Moussa B.H. Youdim, Anthony S. Basile, B. R. De Costa, Ian A. Paul, Gemma A. J. Kuijpers, Harvey B. Pollard, Phil Skolnick, Eduardo Rojas
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 7(12)
Neither the physiological function of sigma (sigma) receptors nor the cellular mechanism responsible for the pharmacological effects of sigma receptor ligands is known. We now report that sigma receptor ligands noncompetitively inhibit nicotine-stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958750e10dc6e9aef4ad06e6f99ea402
https://pubmed.ncbi.nlm.nih.gov/8375616
https://pubmed.ncbi.nlm.nih.gov/8375616
Publikováno v:
Microscopy research and technique. 21(1)
Human SW 1116 colon carcinoma cells were grown on matrix-covered coverslips and flat embedded in specially prepared gelatin capsules in the hydrophylic resin LR White. Dehydration and polymerization were carried out so as to maximize preservation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92725eb6323a29824d172f6dc920861
https://pubmed.ncbi.nlm.nih.gov/1591409
https://pubmed.ncbi.nlm.nih.gov/1591409