Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gemma V. White"'
Autor:
Paul Shaw, Storm J. Hassell-Hart, Gayle E. Douglas, Andrew G. Malcolm, Alan R. Kennedy, Gemma V. White, Laura C. Paterson, William J. Kerr
We report here the application of silyl enol ether moieties as efficient alkene coupling partners within cobalt-mediated intramolecular Pauson-Khand reactions. This cyclization strategy delivers synthetically valuable oxygenated cyclopentenone produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af528aeb5cd77acc05de4638b7d9a905
https://strathprints.strath.ac.uk/80138/1/Shaw_etal_OL_2022_Oxygenated_cyclopentenones_via_the_Pauson_Khand_reaction.pdf
https://strathprints.strath.ac.uk/80138/1/Shaw_etal_OL_2022_Oxygenated_cyclopentenones_via_the_Pauson_Khand_reaction.pdf
Autor:
Yoshiaki Washio, Alan Nadin, Mike Barker, Peter Pogány, Darren V. S. Green, Gemma V. White, Anthony W. J. Cooper, Stephen D. Pickett, Graham George Adam Inglis, Sebastien Andre Campos, Jacob T. Bush, Darren L Poole, John Pritchard, Vipulkumar Kantibhai Patel, Andrew Baxter, David Jonathan Hirst
Publikováno v:
Journal of Medicinal Chemistry. 63:11964-11971
Machine learning approaches promise to accelerate and improve success rates in medicinal chemistry programs by more effectively leveraging available data to guide a molecular design. A key step of an automated computational design algorithm is molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaade1fbb3d97867eecd66229c56d4cc
https://doi.org/10.1021/acs.jmedchem.0c01148
https://doi.org/10.1021/acs.jmedchem.0c01148
Autor:
Sebastien Andre Campos, Gemma V. White, Francesca Zappacosta, Daniel Thomas, John P. Evans, Vipulkumar Kantibhai Patel, Nicholas C. O. Tomkinson, Julie C. L. Fournier
Covalent inhibition is a powerful strategy to develop potent and selective small molecule kinase inhibitors. Targeting the conserved catalytic lysine is an attractive method for selective kinase inactivation. We have developed novel, selective inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6a7e195de5074c360ee374d9748d77
https://strathprints.strath.ac.uk/78022/1/Fournier_etal_CB_2021_Acetylation_of_the_catalytic_lysine_inhibits_kinase_activity.pdf
https://strathprints.strath.ac.uk/78022/1/Fournier_etal_CB_2021_Acetylation_of_the_catalytic_lysine_inhibits_kinase_activity.pdf
Autor:
Panayiotis A. Procopiou, Rachael A. Ancliff, Mark J. Bamford, Christopher Browning, Helen Connor, Susannah Davies, Yvonne C. Fogden, Simon T. Hodgson, Duncan S. Holmes, Brian E. Looker, Karen M. L. Morriss, Christopher A. Parr, Elizabeth A. Pickup, Sanjeet S. Sehmi, Gemma V. White, Clarissa J. Watts, David M. Wilson, Michael D. Woodrow
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 26, p6706-6717, 12p