The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner

Autor: Gemma Roest, Evelien Hesemans, Kirsten Welkenhuyzen, Tomas Luyten, Nikolai Engedal, Geert Bultynck, Jan B. Parys

Publikováno v: Cells, Vol 7, Iss 12, p 239 (2018)

Accumulation of misfolded proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to reduce protein load and restore homeostasis, including via induction of autophagy. We used the proline analogue l-azetidine-2-carbox

Externí odkaz: https://doaj.org/article/f62e5acc6fb24b339abbc9b9f2d2f040

The ER Stress Inducer l-Azetidine-2-Carboxylic Acid Elevates the Levels of Phospho-eIF2α and of LC3-II in a Ca2+-Dependent Manner

Autor: Kirsten Welkenhuyzen, Jan B. Parys, Tomas Luyten, Gemma Roest, Geert Bultynck, Nikolai Engedal, Evelien Hesemans

Publikováno v: Cells, Vol 7, Iss 12, p 239 (2018)
Cells
Volume 7
Issue 12

Accumulation of misfolded proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) to reduce protein load and restore homeostasis, including via induction of autophagy. We used the proline analogue l-azetidine-2-carbox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809985e7955e2674e0d192644ea02818
https://lirias.kuleuven.be/handle/123456789/631051

IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer

Autor: Jan B. Parys, Geert Bultynck, Gemma Roest, Tim Vervliet, Elzbieta Kania

Publikováno v: Frontiers in Oncology
Frontiers in Oncology, Vol 7 (2017)

Calcium ions (Ca2+) play a complex role in orchestrating diverse cellular processes, including cell death and survival. To trigger signaling cascades, intracellular Ca2+ is shuffled between the cytoplasm and the major Ca2+ stores, the endoplasmic ret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c96d2d4aee29391523f1ffd20d04e1b
https://doi.org/10.3389/fonc.2017.00140

From red to blue to far-red in Lhca4: how does the protein modulate the spectral properties of the pigments?

Autor: Emilie Wientjes, Gemma Roest, Roberta Croce

Publikováno v: Wientjes, I E, Roest, G J & Croce, R 2012, ' From blue to red to far-red in Lhca4: how does the protein modulate the spectral properties of the pigments? ', Biochimica et Biophysica Acta (BBA)-Bioenergetics, vol. 1817, pp. 711-717 . https://doi.org/10.1016/j.bbabio.2012.02.030
Biochimica et Biophysica Acta (BBA)-Bioenergetics, 1817, 711-717. Elsevier
Biochimica et Biophysica Acta, 1817(5), 711-717

The first event of photosynthesis is the harvesting of solar energy by a large array of pigments. These pigments are coordinated to proteins that organize them to assure efficient excitation energy transfer. The protein plays an essential role in tun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52c93ebbd256780053a948d5067f92d
https://pubmed.ncbi.nlm.nih.gov/22406625