Multi-centre validation of a flow cytometry method to identify optimal responders to interferon-beta in multiple sclerosis

Autor: Guadalupe Herrera, Elisenda Alari-Pahissa, Alexandru Vlagea, David San Segundo, Juana Gil-Herrera, María Gema Salgado, J. M. Ferrer, Silvia Presas-Rodríguez, Cecilia Muñoz-Calleja, Juan Pablo Cuello, Patricia Urbaneja, Carmen Cámara, Herena Eixarch, Luisa M. Villar, Breogán Rodríguez-Acevedo, Rocío Hernández-Clares, Luis Querol, Eugenia Martinez-Hernandez, Virginia Meca-Lallana, Francisco Gascón-Gimenez, Tamara Castillo-Triviño, María Jesús Pinto-Medel, Jose E Martínez-Rodríguez, Margarita Massot, Agustín Oterino, Aina Teniente-Serra, Alfonso Muriel, Ernesto Roldán, Larraitz Aragón, Montserrat Gómez-Gutiérrez, Esther Moga, Eulalia Rodríguez-Martín, Noelia Villarrubia, Alvaro Prada

Publikováno v: CLINICA CHIMICA ACTA
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Clinica Chimica Acta
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

Background and objectives: Percentages of blood CD19 + CD5 + B cells and CD8 + perforin + T lymphocytes can predict response to Interferon (IFN)-beta treatment in relapsing-remitting multiple sclerosis (RRMS) patients. We aimed to standardize their d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df68d100788243bef2c87c45c5567e7c
https://pubmed.ncbi.nlm.nih.gov/30408481

HLA-C antibodies are associated with irreversible rejection in kidney transplantation: Shared molecular eplets characterization

Autor: Manuel Muro, Santiago Llorente, Jorge Eguia, Luisa Jimeno, Ruth López-Hernández, Anna Mrowiec, Alfredo Minguela, Francisco Boix, José A. Campillo, Alexandre Bosch, María R. Álvarez-López, Gema Salgado, María R. Moya-Quiles

Publikováno v: Human Immunology. 75:338-341

We report an interesting case concerning an irreversible antibody-mediated rejection (AMR), associated with anti-HLA-C DSA, which occurred after a second kidney transplantation despite having determined a low number of antibodies directed against HLA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e489ba43146d1861b90b65ec46874925
https://doi.org/10.1016/j.humimm.2014.01.010

HLA-DRB1 and HLA-DQB1 genes on susceptibility to and protection from allergic bronchopulmonary aspergillosis in patients with cystic fibrosis

Autor: Francisco Boix, María R. Álvarez-López, José A. Campillo, Alfredo Minguela, Ruth López-Hernández, Ana M. García-Alonso, María R. Moya-Quiles, María Dolores Pastor-Vivero, Manuel Muro, Pedro Mondejar-Lopez, Manuel Sanchez-Solis, Gema Salgado

Publikováno v: Microbiology and Immunology. 57:193-197

Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity pulmonary disease that affects both patients with cystic fibrosis (CF) and those with asthma. HLA-DRB1 alleles have previously been associated with ABPA–CF susceptibility; however

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa5505a5f9408902e0ab5d6dcd8155af
https://doi.org/10.1111/1348-0421.12020

Influence of human leukocyte antigen mismatching on rejection development and allograft survival in liver transplantation: Is the relevance of HLA-A locus matching being underestimated?

Autor: María R. Moya-Quiles, José A. Campillo, Alexandre Bosch, Carmen Botella, Alfredo Minguela, Francisco Boix, Gema Salgado, Luis Marín, M.R. Lopez-Alvarez, Manuel Miras, Jesús de la Peña-Moral, Ruth López-Hernández, Manuel Muro, María R. Álvarez-López, Francisco Sánchez-Bueno, Jose Miguel Bolarín, Noelia Pérez, Pedro Gil Martínez, Ricardo Robles, Helios Martínez, Ana M. García-Alonso

Publikováno v: Transplant Immunology. 26:88-93

The influence of HLA matching on liver transplant is still controversial, as studies have failed to demonstrate an adverse effect of HLA mismatching on transplant outcome. We examined the effect of HLA mismatching on transplant outcome in a series of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043a876542f2c2db93b57914cf529ea4
https://doi.org/10.1016/j.trim.2011.11.006

Specific 'intra-allele' and 'intra–broad antigen' human leukocyte antigen alloantibodies in kidney graft transplantation

Autor: Manuela López, Carmen Botella, Francisco Boix, Gema Salgado, Ruth López, María J. González-Soriano, Pedro Gil Martínez, José A. Campillo, María R. Álvarez-López, Alfredo Minguela, Manuel Muro, Santiago Llorente, Luisa Gimeno

Publikováno v: Human Immunology. 71:857-860

Human leukocyte antigen (HLA) antibodies are epitope specific and not antigen specific. This work presents a case of intra-allele (IA) sensitization. A 40-year-old-man underwent transplantion with identical "broad" DR. He was apparently not sensitize

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3793071f835de6616a1ee94b0fd77e62
https://doi.org/10.1016/j.humimm.2010.05.018