Zobrazeno 1 - 10
of 231
pro vyhledávání: '"Gema MORENO-BUENO"'
Autor:
Carlos Casas-Arozamena, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Eva Diaz, Sara S Oltra, Cristian Pablo Moiola, Silvia Cabrera, Alexandra Cortegoso, Teresa Curiel, Alicia Abalo, Mónica Pamies Serrano, Santiago Domingo, Pablo Padilla-Iserte, Marta Arnaez de la Cruz, Alicia Hernández, Virginia García-Pineda, Juan Ruiz-Bañobre, Rafael López, Xavier Matias-Guiu, Eva Colás, Antonio Gil-Moreno, Miguel Abal, Gema Moreno-Bueno, Laura Muinelo-Romay
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background There has been a rise in endometrial cancer (EC) incidence leading to increased mortality. To counter this trend, improving the stratification of post-surgery recurrence risk and anticipating disease relapse and treatment resistan
Externí odkaz:
https://doaj.org/article/d684ea05bd3b4749890be7772b452478
Autor:
Carlos Marugán, Natalia Sanz‐Gómez, Beatriz Ortigosa, Ana Monfort‐Vengut, Cristina Bertinetti, Ana Teijo, Marta González, Alicia Alonso de la Vega, María José Lallena, Gema Moreno‐Bueno, Guillermo deCárcer
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1531-1551 (2024)
Chromosomal instability (CIN) is a hallmark of cancer aggressiveness, providing genetic plasticity and tumor heterogeneity that allows the tumor to evolve and adapt to stress conditions. CIN is considered a cancer therapeutic biomarker because health
Externí odkaz:
https://doaj.org/article/3ef5cfa6ef0a445999dcca9dcaa443a0
Autor:
Rocío Rosas-Alonso, Julian Colmenarejo-Fernández, Olga Pernía, Miranda Burdiel, Carlos Rodríguez-Antolín, Itsaso Losantos-García, Tania Rubio, Rocío Moreno-Velasco, Isabel Esteban-Rodríguez, Virginia Martínez-Marín, Paloma Yubero, Nicolas Costa-Fraga, Angel Díaz-Lagares, Rafael López-López, Eva Díaz-Martin, Juan F. García, Catalina Vivancos Sánchez, Maria Luisa Gandía-González, Gema Moreno-Bueno, Javier de Castro, Inmaculada Ibánez de Cáceres
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Glioblastoma (GB) is a devastating tumor of the central nervous system characterized by a poor prognosis. One of the best-established predictive biomarker in IDH-wildtype GB is O6-methylguanine-DNA methyltransferase (MGMT) methylation (mMGMT
Externí odkaz:
https://doaj.org/article/e4a8484a046145d48a70e38e2c8d1575
Autor:
Isabel Tundidor, Marta Seijo-Vila, Sandra Blasco-Benito, María Rubert-Hernández, Gema Moreno-Bueno, Laura Bindila, Rubén Fernández de la Rosa, Manuel Guzmán, Cristina Sánchez, Eduardo Pérez-Gómez
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract Mammary gland development occurs primarily in adulthood, undergoing extensive expansion during puberty followed by cycles of functional specialization and regression with every round of pregnancy/lactation/involution. This process is ultimat
Externí odkaz:
https://doaj.org/article/3d512f49edd5494f82227c64f367f738
Autor:
Isabel Tundidor, Marta Seijo-Vila, Sandra Blasco-Benito, María Rubert-Hernández, Sandra Adámez, Clara Andradas, Sara Manzano, Isabel Álvarez-López, Cristina Sarasqueta, María Villa-Morales, Carmen González-Lois, Esther Ramírez-Medina, Belén Almoguera, Antonio J. Sánchez-López, Laura Bindila, Sigrid Hamann, Norbert Arnold, Christoph Röcken, Ignacio Heras-Murillo, David Sancho, Gema Moreno-Bueno, María M. Caffarel, Manuel Guzmán, Cristina Sánchez, Eduardo Pérez-Gómez
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Clinical management of breast cancer (BC) metastasis remains an unmet need as it accounts for 90% of BC-associated mortality. Although the luminal subtype, which represents >70% of BC cases, is generally associated with a favorable outcome,
Externí odkaz:
https://doaj.org/article/ab9e0b407ed94740a55b818db99ef737
Autor:
Manuel Gámez-Chiachio, Ángela Molina-Crespo, Carmen Ramos-Nebot, Jeannette Martinez-Val, Lidia Martinez, Katja Gassner, Francisco J. Llobet, Mario Soriano, Alberto Hernandez, Marco Cordani, Cristina Bernadó-Morales, Eva Diaz, Alejandro Rojo-Sebastian, Juan Carlos Triviño, Laura Sanchez, Ruth Rodríguez-Barrueco, Joaquín Arribas, David Llobet-Navás, David Sarrió, Gema Moreno-Bueno
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Gasdermin B (GSDMB) over-expression promotes poor prognosis and aggressive behavior in HER2 breast cancer by increasing resistance to therapy. Decoding the molecular mechanism of GSDMB-mediated drug resistance is crucial to identi
Externí odkaz:
https://doaj.org/article/f27d67a436224cd7aff26d109a24a883
Autor:
Gracia Mendoza, Rebeca González-Pastor, Juan Miguel Sánchez, Altamira Arce-Cerezo, Miguel Quintanilla, Gema Moreno-Bueno, Anna Pujol, Carolina Belmar-López, Alba de Martino, Efrén Riu, Tristan A. Rodriguez, Pilar Martin-Duque
Publikováno v:
Cells, Vol 12, Iss 9, p 1338 (2023)
The induction of pluripotency by enforced expression of different sets of genes in somatic cells has been achieved with reprogramming technologies first described by Yamanaka’s group. Methodologies for generating induced pluripotent stem cells are
Externí odkaz:
https://doaj.org/article/462c51c03615408780b575f630aba79d
Publikováno v:
EJC Supplements, Vol 15, Iss , Pp 16-26 (2020)
Background and purpose: Ovarian cancer (OC) is the deadliest gynaecologic cancer characterised by a high heterogeneity not only at the clinical point of view but also at the molecular level. This review focuses on the new insights about the OC molecu
Externí odkaz:
https://doaj.org/article/f6036d37a53a4125b667b2308bb373b2
Autor:
David Sarrio, Alejandro Rojo-Sebastián, Ana Teijo, María Pérez-López, Eva Díaz-Martín, Lidia Martínez, Saleta Morales, Pablo García-Sanz, José Palacios, Gema Moreno-Bueno
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Gasdermins (GSDM) genes play complex roles in inflammatory diseases and cancer. Gasdermin-B (GSDMB) is frequently upregulated in human cancers, especially in HER2-amplified breast carcinomas, and can promote diverse pro-tumor functions (invasion, met
Externí odkaz:
https://doaj.org/article/e900e82dc41b438d978cdff35ba16c98
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Adipose tissue secretes various peptides, including leptin. This hormone acts through the leptin receptor (Ob-R), which is expressed ubiquitously on the surface of various cells, including breast cancer cells and immune cells. Increasing evidence poi
Externí odkaz:
https://doaj.org/article/ef83cb9a6bc64c839e9db2f3d11410e1