Does HLA explain the high incidence of childhood-onset type 1 diabetes in the Canary Islands? The role of Asp57 DQB1 molecules

Autor: Yeray Nóvoa-Medina, Itahisa Marcelino-Rodriguez, Nicolás M. Suárez, Marta Barreiro-Bautista, Eva Rivas-García, Santiago Sánchez-Alonso, Gema González-Martínez, Sofía Quinteiro-González, Ángela Domínguez, María Cabrera, Sara López, Svetlana Pavlovic, Carlos Flores, Gran Canarian Diabetes and Obesity Research Group, Ana M. Wägner

Publikováno v: BMC Pediatrics, Vol 24, Iss 1, Pp 1-12 (2024)

Abstract The Canary Islands inhabitants, a recently admixed population with significant North African genetic influence, has the highest incidence of childhood-onset type 1 diabetes (T1D) in Spain and one of the highest in Europe. HLA accounts for ha

Externí odkaz: https://doaj.org/article/e088d419d45649918f94dcbd461f893e

Immunogenicity of a third dose with mRNA-vaccines in the ChAdOx1-S/BNT162b2 vaccination regimen against SARS-CoV-2 variants

Autor: Javier García-Pérez, Alberto M. Borobia, Mayte Pérez-Olmeda, Antonio Portolés, Luis Castaño, Magdalena Campins-Artí, María Jesús Bertrán, Mercedes Bermejo, José Ramón Arribas, Andrea López, Ana Ascaso-del-Rio, Eunate Arana-Arri, Inmaculada Fuentes Camps, Anna Vilella, Almudena Cascajero, María Teresa García-Morales, María Castillo de la Osa, Carla Pérez Ingidua, David Lora, Paloma Jiménez-Santana, Silvia Pino-Rosa, Agustín Gómez de la Cámara, Erick De La Torre-Tarazona, Esther Calonge, Raquel Cruces, Cristóbal Belda-Iniesta, José Alcamí, Jesús Frías, Antonio J. Carcas, Francisco Díez-Fuertes, Lucía Díaz García, Elena Ramírez García, Enrique Seco Meseguer, Stefan Mark Stewart Balbàs, Alicia Marín Candón, Irene García García, Mikel Urroz Elizalde, Paula de la Rosa, Marta Sanz García, Cristina López Crespo, Vega Mauleón Martínez, Raquel de Madariaga Castell, Laura Vitón Vara, Rocío Prieto-Pérez, Emilio Vargas-Castrillón, Leonor Laredo, Ouhao Zhu-Huang, Teresa Iglesias, Natale Imaz-Ayo, Susana Meijide, Aitor García de Vicuña, Ana Santorcuato, Iraide Exposito, Sara de Benito, Alazne Bustinza, Mikel Gallego, Dolores García-Vázquez, Ana Belén de la Hoz, Gustavo Pérez-Nanclares, Josu Aurrekoetxea, Ines Urrutia, Rosa Martínez-Salazar, Janire Orcajo, Begoña Calvo, June Corcuera, Olaia Velasco, Anibal Aguayo, Xavier Martínez-Gómez, Susana Otero-Romero, Lluis Armadans, Blanca Borras-Bermejo, Oleguer Parés, Sonia Uriona, José Ángel Rodrigo Pendás, Cesar Llorente, José Santos, Laia Pinós, Lina Camacho, Judith Riera, Carla Sans, Antonia Agustí, Carmen Altadill, Carla Aguilar Blancafort, Gisela Gili Serrat, Aitana Plaza, Anna Feliu Prius, Maria Margarita Torrens, Esther Palacio, Gloria Torres, Julia Calonge, Elena Ballarin Alins, Eulàlia Pérez-Esquirol, Lourdes Vendrell Bosch, Marta Aldea, Eugènia Mellado, Ma Ángeles Marcos, Marta Tortajada, Lourdes E. Barón-Mira, Laura Granés, Sulayman Lazaar, Sara Herranz, Montserrat Malet, Sebastiana Quesada, Anna Llupià, Victoria Olivé, Antoni Trilla, Begoña Gómez, Elisenda González, Sheila Romero, Francisco Javier Gámez, Cristina Casals, Laura Burunat, Juan José Castelló, Patricia Fernández, Josep Lluís Bedini, Jordi Vila, Juan Carlos Hurtado, Isabel Jado, Giovanni Fedele, Concepción Perea, Mónica González, Isabel Grajera, María Ángeles Murillo, Pilar Balfagón, Irene Díaz-Marín, Gema González-Pardo

Publikováno v: iScience, Vol 27, Iss 9, Pp 110728- (2024)

Summary: CombiVacS study has demonstrated a strong immune response of the heterologous ChAdOx1-S/BNT162b2 vaccine combination. The primary outcomes of the study were to assess the humoral immune response against SARS-CoV-2, 28 days after a third dose

Externí odkaz: https://doaj.org/article/1d8485bc140e4998a160d76238a98bff

Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)2-Functionalized Carbon Nanotubes for Glucose Detection

Autor: Diego Bolaños-Mendez, Lenys Fernández, Rafael Uribe, Alisson Cunalata-Castro, Gema González, Isamara Rojas, Andrés Chico-Proano, Alexis Debut, Luis Alberto Celi, Patricio Espinoza-Montero

Publikováno v: Sensors, Vol 24, Iss 23, p 7707 (2024)

This work reports on the assessment of a non-hydrolytic electrochemical sensor for glucose sensing that is developed using functionalized carbon nanotubes (fCNTs)/Co(OH)2. The morphology of the nanocomposite was investigated by scanning electron micr

Externí odkaz: https://doaj.org/article/18b671b81dda4d8887e0011e9b95718b

Microcrystalline Luminescent (Eu1-xLnx)2bdc3·nH2O (Ln = La, Gd, Lu) Antenna MOFs: Effect of Dopant Content on Structure, Particle Morphology, and Luminescent Properties

Autor: Stefaniia S. Kolesnik, Nikita A. Bogachev, Ilya E. Kolesnikov, Sergey N. Orlov, Mikhail N. Ryazantsev, Gema González, Mikhail Yu. Skripkin, Andrey S. Mereshchenko

Publikováno v: Molecules, Vol 29, Iss 2, p 532 (2024)

In this work, three series of micro-sized heterometallic europium-containing terephthalate MOFs, (Eu1-xLnx)2bdc3·nH2O (Ln = La, Gd, Lu), are synthesized via an ultrasound-assisted method in an aqueous medium. La3+ and Gd3+-doped terephthalates are i

Externí odkaz: https://doaj.org/article/466f2fa8780d48d1ba3c271a686a84aa

Evaluation of an electrochemical biosensor based on carbon nanotubes, hydroxyapatite and horseradish peroxidase for the detection of hydrogen peroxide

Autor: Jocelyne Alvarez-Paguay, Lenys Fernández, Diego Bolaños-Méndez, Gema González, Patricio J. Espinoza-Montero

Publikováno v: Sensing and Bio-Sensing Research, Vol 37, Iss , Pp 100514- (2022)

Evaluation of an electrochemical biosensor based on glassy carbon (GC) electrode that was modified with multiwall carbon nanotubes (MWCNTs), which in turn were modified with hydroxyapatite (HAp) and horseradish peroxidase (HRP), for the detection of

Externí odkaz: https://doaj.org/article/99c96f44ebac4e01a7731267ef65a394