Zobrazeno 1 - 10
of 490
pro vyhledávání: '"Gema Frühbeck"'
Autor:
Jaime López-Alcalá, Ana Gordon, Andrés Trávez, Carmen Tercero-Alcázar, Alejandro Correa-Sáez, María Jesús González-Rellán, Oriol A. Rangel-Zúñiga, Amaia Rodríguez, Antonio Membrives, Gema Frühbeck, Rubén Nogueiras, Marco A. Calzado, Rocío Guzmán-Ruiz, María M. Malagón
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-28 (2024)
Abstract Background Excessive lipid accumulation in the adipose tissue in obesity alters the endocrine and energy storage functions of adipocytes. Adipocyte lipid droplets represent key organelles coordinating lipid storage and mobilization in these
Externí odkaz:
https://doaj.org/article/67e13ce9f2ae45388dd0b4f7ac1984d8
Autor:
J. Karina Zapata, M. Cristina Azcona-Sanjulian, Victoria Catalán, Beatriz Ramírez, Camilo Silva, Amaia Rodríguez, Javier Escalada, Gema Frühbeck, Javier Gómez-Ambrosi
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-10 (2023)
Abstract Objective To assess how inaccurately the body mass index (BMI) is used to diagnose obesity compared to body fat percentage (BF%) measurement and to compare the cardiometabolic risk in children and adolescents with or without obesity accordin
Externí odkaz:
https://doaj.org/article/89cfbe22a2394f7e84c9949f88ea794d
Autor:
Maria J. Gonzalez-Rellan, Tamara Parracho, Violeta Heras, Amaia Rodriguez, Marcos F. Fondevila, Eva Novoa, Natalia Lima, Marta Varela-Rey, Ana Senra, Maria D.P. Chantada-Vazquez, Cristina Ameneiro, Ganeko Bernardo, David Fernandez-Ramos, Fernando Lopitz-Otsoa, Jon Bilbao, Diana Guallar, Miguel Fidalgo, Susana Bravo, Carlos Dieguez, Maria L. Martinez-Chantar, Oscar Millet, Jose M. Mato, Markus Schwaninger, Vincent Prevot, Javier Crespo, Gema Frühbeck, Paula Iruzubieta, Ruben Nogueiras
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101776- (2023)
Objective: O-GlcNAcylation is a post-translational modification that directly couples the processes of nutrient sensing, metabolism, and signal transduction, affecting protein function and localization, since the O-linked N-acetylglucosamine moiety c
Externí odkaz:
https://doaj.org/article/534b9501b49e4a008f0846e144ff4da3
Autor:
Maite Aguas-Ayesa, Patricia Yárnoz-Esquiroz, Laura Olazarán, Carolina M. Perdomo, Marta García-Goñi, Patricia Andrada, Javier Escalada, Camilo Silva, Ascensión Marcos, Gema Frühbeck
Publikováno v:
Nutrients, Vol 15, Iss 22, p 4824 (2023)
Unhealthy dietary habits and sedentarism coexist with a rising incidence of excess weight and associated comorbidities. We aimed to analyze the dietary and drinking patterns of patients with excess weight, their main characteristics, plausible gender
Externí odkaz:
https://doaj.org/article/a3eecc99d51245eab15febf0b39fd586
Autor:
Aarón Otero, Sara Becerril, Marina Martín, Javier A. Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi, María A. Burrell, Gema Frühbeck, Amaia Rodríguez
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionObesity contributes to ectopic fat deposition in non-adipose organs, including the pancreas. Pancreas steatosis associates with inflammation and β-cell dysfunction, contributing to the onset of insulin resistance and type 2 diabetes. An
Externí odkaz:
https://doaj.org/article/a67e37be52534e13972180aa549273c8
Autor:
Carolina M. Perdomo, Ana Ezponda, Jorge M. Núñez-Córdoba, José I. Herrero, Gorka Bastarrika, Gema Frühbeck, Javier Escalada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Non-alcoholic fatty liver disease (NAFLD) is associated with cardiovascular disease morbimortality. However, it is not clear if NAFLD staging may help identify early or subclinical markers of cardiovascular disease. We aimed to evaluate the
Externí odkaz:
https://doaj.org/article/06cbde148f5748b088c6a8867e6072a6
Autor:
Lorenzo M. Donini, Luca Busetto, Stephan C. Bischoff, Tommy Cederholm, Maria D. Ballesteros-Pomar, John A. Batsis, Juergen M. Bauer, Yves Boirie, Alfonso J. Cruz-Jentoft, Dror Dicker, Stefano Frara, Gema Frühbeck, Laurence Genton, Yftach Gepner, Andrea Giustina, Maria Cristina Gonzalez, Ho-Seong Han, Steven B. Heymsfield, Takashi Higashiguchi, Alessandro Laviano, Andrea Lenzi, Ibolya Nyulasi, Edda Parrinello, Eleonora Poggiogalle, Carla M. Prado, Javier Salvador, Yves Rolland, Ferruccio Santini, Mireille J. Serlie, Hanping Shi, Cornel C. Sieber, Mario Siervo, Roberto Vettor, Dennis T. Villareal, Dorothee Volkert, Jianchun Yu, Mauro Zamboni, Rocco Barazzoni
Publikováno v:
Obesity Facts, Pp 1-15 (2022)
Introduction: Loss of skeletal muscle mass and function (sarcopenia) is common in individuals with obesity due to metabolic changes associated with a sedentary lifestyle, adipose tissue derangements, comorbidities (acute and chronic diseases) and dur
Externí odkaz:
https://doaj.org/article/d1276094cfe743eb9365d15d78027e81
Autor:
Gema Frühbeck, Javier Gómez-Ambrosi, Beatriz Ramírez, Amaia Mentxaka, Amaia Rodríguez, Sara Becerril, Gabriel Reina, Victor Valentí, Rafael Moncada, Camilo Silva, Victoria Catalán
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/4c06e28e42cd41c4a26de91d103d77ca
Autor:
Carolina M. Perdomo, Jorge M. Núñez-Córdoba, Ana Ezponda, Francisco J. Mendoza, Javier Ampuero, Gorka Bastarrika, Gema Frühbeck, Javier Escalada
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundTo better understand the patient's heterogeneity in fatty liver disease (FLD), metabolic dysfunction–associated fatty liver disease (MAFLD) was proposed by international experts as a new nomenclature for nonalcoholic fatty liver disease (
Externí odkaz:
https://doaj.org/article/5faaf15439c54fd4ae2f6c81711316a9
Autor:
Gema Frühbeck, Leire Méndez-Giménez, Sara Becerril, Beatriz Ramírez, Ana Wenting Hernández-Pardos, Javier A. Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi, Inês V. da Silva, Graça Soveral, Amaia Rodríguez
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3412 (2023)
Glycerol is a key metabolite for lipid accumulation in insulin-sensitive tissues. We examined the role of aquaporin-7 (AQP7), the main glycerol channel in adipocytes, in the improvement of brown adipose tissue (BAT) whitening, a process whereby brown
Externí odkaz:
https://doaj.org/article/c2ba23ed6c62498bae85e6cde5229e7b