Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Gema Atienza"'
1
Akademický článek
A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages.
Autor: Maria C Maldifassi, Gema Atienza, Francisco Arnalich, Eduardo López-Collazo, Jose L Cedillo, Carolina Martín-Sánchez, Anna Bordas, Jaime Renart, Carmen Montiel
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e108397 (2014)
Nicotine stimulation of α7 nicotinic acetylcholine receptor (α7 nAChR) powerfully inhibits pro-inflammatory cytokine production in lipopolysaccharide (LPS)-stimulated macrophages and in experimental models of endotoxemia. A signaling pathway downst
Externí odkaz: https://doaj.org/article/04c777d9f5b74cb6b7382f262c888fb4
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2
The human-specific duplicated α7 gene inhibits the ancestral α7, negatively regulating nicotinic acetylcholine receptor-mediated transmitter release
Autor: Gema Atienza, Eva Alés, Arturo Chávez-Reyes, Carolina Martín-Sánchez, Francisco Arnalich, José Luis Cedillo, Anna Bordas, Santiago Balseiro-Gomez, Carmen Montiel, María Extremera
Publikováno v: The Journal of Biological Chemistry
Gene duplication generates new functions and traits, enabling evolution. Human-specific duplicated genes in particular are primary sources of innovation during our evolution although they have very few known functions. Here we examine the brain funct
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a881750a98efc25dc22b75c59d0177a
http://europepmc.org/articles/PMC7949125
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3
Expression patterns for nicotinic acetylcholine receptor subunit genes in smoking-related lung cancers
Autor: Gema Atienza, Carmen Fernández-Capitán, Anna Bordas, Carolina Martín-Sánchez, Isabel Esteban-Rodríguez, Carmen Montiel, Francisco Arnalich, J. J. Rios, Laura Guerra-Pastrián, Javier de Castro, José Luis Cedillo
Publikováno v: Oncotarget
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Cigarette smoking is associated with increased risk for all histologic types of lung cancer, but why the strength of this association is stronger for squamous cell carcinoma than adenocarcinoma of the lung (SQC-L, ADC-L) is not fully understood. Beca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c74af39ce3088283240efaea4e52bc4
https://doi.org/10.18632/oncotarget.18948
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4
Anti-tumoral activity of the human-specific duplicated form of α7-nicotinic receptor subunit in tobacco-induced lung cancer progression
Autor: J. J. Rios, Gema Atienza, Raquel L Arribas, Isabel Esteban-Rodríguez, José Luis Cedillo, Anna Bordas, Carolina Martín-Sánchez, Francisco Arnalich, Carmen Montiel, María Extremera
Publikováno v: Lung cancer (Amsterdam, Netherlands). 128
Objectives: Tobacco smoking is strongly correlated with the onset and progression of non-small cell lung cancer (NSCLC). By activating α7 nicotinic acetylcholine receptors (α7-nAChRs) in these tumors nicotine and its tobacco-derived nitrosamine, NN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5abd583304f90ceb55f0dbc42c1abb
https://pubmed.ncbi.nlm.nih.gov/30642446
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5
Interaction of the α7-nicotinic subunit with its human-specific duplicated dupα7 isoform in mammalian cells: Relevance in human inflammatory responses
Autor: Gema Atienza, Anna Bordas, Cecilio Giménez, Francisco Zafra, Carolina Martín-Sánchez, Maria Constanza Maldifassi, José Luis Cedillo, Carmen Montiel, Francisco Arnalich, María Extremera, Jaime Renart
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
The α7 nicotinic receptor subunit and its partially duplicated human-specific dupα7 isoform are coexpressed in neuronal and non-neuronal cells. In these cells, α7 subunits form homopentameric α7 nicotinic acetylcholine receptors (α7-nAChRs) impl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddc6c3212b94408e9d55bfa849a9d0b
http://hdl.handle.net/10261/188232
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6
Function of Partially Duplicated Human α7 Nicotinic Receptor Subunit CHRFAM7A Gene
Autor: Francisco Arnalich, Jaime Renart, Gema Atienza, Eva Andres-Mateos, Carmen Montiel, M. Constanza Maldifassi, Ana M. de Lucas-Cerrillo, Jesús Cruces, Rocío Serantes, Aurora Sánchez-Pacheco
Publikováno v: Journal of Biological Chemistry. 286:594-606
The neuronal α7 nicotinic receptor subunit gene (CHRNA7) is partially duplicated in the human genome forming a hybrid gene (CHRFAM7A) with the novel FAM7A gene. The hybrid gene transcript, dupα7, has been identified in brain, immune cells, and the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8a2ddd7cdfd75dabf280f9a6a6ffae83
https://doi.org/10.1074/jbc.m110.180067
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8
A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages
Autor: Anna Bordas, Maria Constanza Maldifassi, Carolina Martín-Sánchez, Gema Atienza, Eduardo López-Collazo, José Luis Cedillo, Jaime Renart, Francisco Arnalich, Carmen Montiel
Publikováno v: PLoS ONE, Vol 9, Iss 9, p e108397 (2014)
Digital.CSIC. Repositorio Institucional del CSIC
instname
PLoS ONE
This is an open-access article distributed under the terms of the Creative Commons Attribution License.-- et al.
Nicotine stimulation of α7 nicotinic acetylcholine receptor (α7 nAChR) powerfully inhibits pro-inflammatory cytokine production in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdaae15ae069655f52f258b268085971
http://europepmc.org/articles/PMC4178160?pdf=render
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9
Decreased vascular endothelial growth factor response to acute hypoglycemia in type 2 diabetic patients with hypoglycemic coma
Autor: Maria Constanza Maldifassi, Rafael Herruzo, Rosa Codoceo, Enrique Ciria, Gema Atienza, Francisco Arnalich, Carmen Montiel, José Luis Cedillo, Jaime Renart, Angustias Quesada
Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
El pdf del artículo es el manuscrito de autor.-- et al.
[Introduction]: Plasma vascular endothelial growth factor (VEGF) was shown to increase during acute hypoglycemia and could mediate rapid adaptation of the brain. In this study we examined
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ea494027ed0c3676a75559fada1d81
http://hdl.handle.net/10261/76705
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10
Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response
Autor: Ana M, de Lucas-Cerrillo, M Constanza, Maldifassi, Francisco, Arnalich, Jaime, Renart, Gema, Atienza, Rocío, Serantes, Jesús, Cruces, Aurora, Sánchez-Pacheco, Eva, Andrés-Mateos, Carmen, Montiel
Publikováno v: The Journal of biological chemistry. 286(1)
The neuronal α7 nicotinic receptor subunit gene (CHRNA7) is partially duplicated in the human genome forming a hybrid gene (CHRFAM7A) with the novel FAM7A gene. The hybrid gene transcript, dupα7, has been identified in brain, immune cells, and the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::71840095ad6c085774797604be2c5066
https://pubmed.ncbi.nlm.nih.gov/21047781
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