Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic.

Autor: Gelzinis JA; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA.; Institute for Cardiovascular & Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK., Szahaj MK; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA., Bekendam RH; Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Wurl SE; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA., Pantos MM; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA., Verbetsky CA; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA., Dufresne A; Baystate Research Facility, Baystate Medical Center, UMass Chan Medical School, Springfield, Massachusetts, USA., Shea M; Division of Oncology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Howard KC; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone St., Lexington, Kentucky, 40536, USA., Tsodikov OV; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone St., Lexington, Kentucky, 40536, USA., Garneau-Tsodikova S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 S. Limestone St., Lexington, Kentucky, 40536, USA., Zwicker JI; Division of Hemostasis and Thrombosis, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA., Kennedy DR; College of Pharmacy and Health Sciences, Western New England University, Springfield, Massachusetts, USA.; Institute for Cardiovascular & Metabolic Research, School of Biological Sciences, University of Reading, Reading, UK.; Department of Medicine, UMass Chan Medical School-Baystate, Springfield, Massachusetts, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 May; Vol. 37 (5), pp. e22914.