Výsledky vyhledávání - "Gelita, Owens"

Oral 1-O-octadecyl-2-O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice

Autor: Lora Melman, Kathy A. Aldern, Gelita Owens, James R. Beadle, Jill Schriewer, Karl Y. Hostetler, Julissa Trahan, R. Mark L. Buller

Publikováno v: Antiviral Research. 73:212-218

Hexadecyloxypropyl-cidofovir (HDP-CDV) has been shown to be orally active against lethal infection with orthopoxviruses including, mousepox, cowpox, vaccinia and rabbitpox. The alkoxyalkyl group provides oral absorption and reduces greatly the amount

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae16e80d5255fac65f3f6499412f5f03
https://doi.org/10.1016/j.antiviral.2006.10.009

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Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model

Autor: Lora Melman, Jill Schriewer, James R. Beadle, Karl Y. Hostetler, R. Mark L. Buller, Gelita Owens

Publikováno v: Virology. 318(2):474-481

Cidofovir (CDV) is a highly effective inhibitor of orthopoxvirus replication and may be used intravenously to treat smallpox or complications arising from the smallpox vaccine under an investigational new drug application (IND). However, CDV is absor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a567f05e41b5e118e2f5c387f08ff637

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Mouse models for studying orthopoxvirus respiratory infections

Autor: Jill, Schriewer, R Mark L, Buller, Gelita, Owens

Publikováno v: Methods in molecular biology (Clifton, N.J.). 269

Concern regarding the use of variola and monkeypox viruses as bioterrorist agents has led to an increased study of orthopoxviruses to understand the molecular and cellular basis of pathogenesis and develop safe and effective antivirals and vaccines a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::694649c33fa39397742943eaa9df8b0f
https://pubmed.ncbi.nlm.nih.gov/15114022

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Mouse Models for Studying Orthopoxvirus Respiratory Infections

Autor: Jill Schriewer, Gelita Owens, R. Mark L. Buller

Publikováno v: Vaccinia Virus and Poxvirology ISBN: 9781588292292

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6e44523b090ffacc9471ebf0749e13c4
https://doi.org/10.1385/1-59259-789-0:289

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