Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16.

Autor: Casey NP; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Kleinmanns K; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway., Forcados C; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Gelebart PF; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway., Joaquina S; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Lode M; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway., Benard E; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Kaveh F; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Caulier B; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway.; Department of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Center for Cancer Cell Reprogramming (CanCell), Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Helgestad Gjerde C; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway., García de Jalón E; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway., Warren DJ; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Lindemann K; Department of Gynecologic Oncology, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Rokkones E; Department of Gynecologic Oncology, Oslo University Hospital, Oslo, Norway., Davidson B; Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Pathology, Division of Laboratory Medicine, Oslo University Hospital, Oslo, Norway., Myhre MR; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Kvalheim G; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Bjørge L; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway., McCormack E; Centre for Cancer Biomarkers CCBIO, Department of Clinical Science, University of Bergen, Bergen, Norway.; Centre for Pharmacy, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway., Inderberg EM; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway., Wälchli S; Translational Research Unit, Section of Cellular Therapy, Department of Oncology, Oslo University Hospital, Oslo, Norway sebastw@rr-research.no.

Publikováno v: Journal for immunotherapy of cancer [J Immunother Cancer] 2024 Apr 11; Vol. 12 (4). Date of Electronic Publication: 2024 Apr 11.