Circulating levels of endogenous complement inhibitors correlate inversely with complement consumption in systemic lupus erythematosus.

Autor: van der Meulen S; Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands., Monahan RC; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, the Netherlands., van Kooten C; Department of Internal Medicine section Nephrology, Center of Expertise for Lupus-, Vasculitis and Complement-mediated Systemic Autoimmune Diseases, Leiden University Medical Center, Leiden, the Netherlands., Teng YKO; Department of Internal Medicine section Nephrology, Center of Expertise for Lupus-, Vasculitis and Complement-mediated Systemic Autoimmune Diseases, Leiden University Medical Center, Leiden, the Netherlands., Huizinga TWJ; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands., Steup-Beekman GM; Department of Rheumatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Rheumatology, Haaglanden Medical Center, The Hague, the Netherlands., Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, the Netherlands.

Publikováno v: European journal of immunology [Eur J Immunol] 2024 Nov; Vol. 54 (11), pp. e2450998. Date of Electronic Publication: 2024 Aug 20.

Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators.

Autor: Wang H; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., van de Bovenkamp FS; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Dijkstra DJ; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., Borggreven NV; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Pool J; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Zuijderduijn R; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Gstöttner C; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, Netherlands., Damelang T; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands., Vidarsson G; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands., Blom AM; Department of Translational Medicine, Section of Medical Protein Chemistry, Lund University, Malmö, Sweden., Domínguez-Vega E; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., Parren PWHI; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Gyes BV, Utrecht, Netherlands., Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 May 16; Vol. 15, pp. 1288597. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).

Safety and pharmacodynamic efficacy of eculizumab in aneurysmal subarachnoid hemorrhage (CLASH): A phase 2a randomized clinical trial.

Autor: Koopman I; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Tack RW; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Wunderink HF; Department of Medical Microbiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Bruns AH; Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., van der Schaaf IC; Department of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Cianci D; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, The Netherlands., van de Ridder IM; Department of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Hol EM; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Rinkel GJ; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Vergouwen MD; Department of Neurology and Neurosurgery, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Publikováno v: European stroke journal [Eur Stroke J] 2023 Dec; Vol. 8 (4), pp. 1097-1106. Date of Electronic Publication: 2023 Aug 22.

Does COVID-19 impact the prevalence of myositis specific antibodies in the Netherlands? A comparative nationwide study.

Autor: Kamperman RG; Department of Neurology, Neuroscience Institute, Amsterdam University Medical Centre (AUMC), location AMC, the Netherlands. Electronic address: r.kamperman@amsterdamumc.nl., van Leeuwen EM; Department of Experimental Immunology, Amsterdam Institute for Infection & Immunity, Amsterdam University Medical Centre (AUMC), location AMC, the Netherlands., Willems M; Department of Neurology, Diakonessenhuis Medical Centre, Utrecht, the Netherlands., van der Kooi AJ; Department of Neurology, Neuroscience Institute, Amsterdam University Medical Centre (AUMC), location AMC, the Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, the Netherlands., Hamann D; Central Diagnostic Laboratory/Centre of Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht, the Netherlands., van Lochem EG; Rijnstate Hospital, Department of Microbiology and Immunology, Arnhem, the Netherlands., Meek B; St. Antonius Hospital, Department of Medical Microbiology and Immunology, Nieuwegein, the Netherlands., van der Molen RG; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud University Medical Center, Nijmegen, the Netherlands., Platteel AC; Rijnstate Hospital, Department of Microbiology and Immunology, Arnhem, the Netherlands., Otten HG; Central Diagnostic Laboratory/Centre of Translational Immunology, University Medical Center (UMC) Utrecht, Utrecht, the Netherlands., Schreurs MW; Laboratory of Medical Microbiology and Immunology, Elisabeth-TweeSteden Hospital, Microvida, Tilburg, the Netherlands., Raaphorst J; Department of Neurology, Neuroscience Institute, Amsterdam University Medical Centre (AUMC), location AMC, the Netherlands.

Publikováno v: Journal of autoimmunity [J Autoimmun] 2023 Sep; Vol. 139, pp. 103081. Date of Electronic Publication: 2023 Jun 12.

Differences in IgG autoantibody Fab glycosylation across autoimmune diseases.

Autor: Koers J; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Sciarrillo R; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Derksen NIL; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Vletter EM; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., Fillié-Grijpma YE; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Raveling-Eelsing E; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Graça NAG; Department of Molecular Hematology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands., Leijser T; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Pas HH; Centre for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Laura van Nijen-Vos L; Centre for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Braham MVJ; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Buisman AM; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., de Jong J; Sanquin Diagnostic Services, Amsterdam, The Netherlands., Schriek AI; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands., Tio-Gillen AP; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., Teng YKO; Department of Nephrology, Leiden University Medical Center, Leiden, The Netherlands., Steenhuis M; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Swaneveld FH; Department of Transfusion Medicine, Sanquin Blood Bank, Amsterdam, The Netherlands., de Taeye SW; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands., van Gils MJ; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands., Verschuuren JJGM; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands., Rutgers B; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Heeringa P; Department of Pathology and Medical Biology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Horváth B; Centre for Blistering Diseases, Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Jacobs BC; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands; Department of Neurology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., de Leeuw K; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Franssen CFM; Department of Internal Medicine, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Veyradier A; Service d'Hématologie biologique, Hôpital Lariboisière and EA-3518 Institut de Recherche Saint Louis, Assistance Publique-Hôpitaux de Paris, Université de Paris, France; Centre de Référence des Microangiopathies Thrombotiques, Hôpital Saint-Antoine, AP-HP, Paris, France., Coppo P; Centre de Référence des Microangiopathies Thrombotiques, Hôpital Saint-Antoine, AP-HP, Paris, France; Service d'Hématologie, Hôpital Saint-Antoine, AP-HP, Paris, France; Faculté de médecine, Sorbonne Université, UPMC Univ Paris, Paris, France., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, The Netherlands., Marieke van Ham S; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands; Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands., van Els CACM; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands; Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands., van der Woude D; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., Huizinga R; Department of Medical Microbiology and Infection Prevention, Laboratory of Experimental Virology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, The Netherlands., Huijbers MG; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Kuijpers TW; Department of Pediatric Hematology, Immunology and Infectious Diseases, Emma Children's Hospital, Amsterdam University Medical Centre, Amsterdam, The Netherlands; Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Toes REM; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands., Bos NA; Department of Rheumatology and Clinical Immunology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands., Rispens T; Department of Immunopathology, Landsteiner Laboratory, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, the Netherlands. Electronic address: t.rispens@sanquin.nl.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2023 Jun; Vol. 151 (6), pp. 1646-1654. Date of Electronic Publication: 2023 Jan 27.