Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gek Huey Chua"'
Autor:
Jie Li, Lesong Mo, Fujie Zhang, Mei Mei, Zhe Xu, Guanghou Shui, Zehua Wang, Chao Zhang, Sin Man Lam, Yingchun Wang, Siyuan Yang, Shaohua Zhang, Gek Huey Chua, Jun Wang, Jin-Wen Song, Zhen Ni, Ming-Ju Zhou, Bowen Li, Lei Shi, Fanping Meng, Bernett Lee, Ming Shi, Shilai Bao, Jiabao Cao, Wen-Jing Cao, Fu-Sheng Wang, Xiahe Huang, Lei Huang
Publikováno v:
Nature Metabolism. 3:909-922
Exosomes represent a subtype of extracellular vesicle that is released through retrograde transport and fusion of multivesicular bodies with the plasma membrane1. Although no perfect methodologies currently exist for the high-throughput, unbiased iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf38e3e2b6a800f32921202bbf962ba
https://doi.org/10.1038/s42255-021-00425-4
https://doi.org/10.1038/s42255-021-00425-4
Autor:
Xiupeng Chen, Jie Li, Zhongbao Gao, Yang Yang, Wenqing Kuang, Yue Dong, Gek Huey Chua, Xiahe Huang, Binhua Jiang, He Tian, Yingchun Wang, Xun Huang, Yan Li, Sin Man Lam, Guanghou Shui
Publikováno v:
National Science Review. 9
While endogenous lipids are known to exhibit rhythmic oscillations, less is known about how specific lipids modulate circadian behavior. Through a series of loss-of-function and gain-of-function experiments on ceramide phosphoethanolamine (CPE) synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ec178eef401d4b1ecbdf93a7608dd74
https://doi.org/10.1093/nsr/nwac148
https://doi.org/10.1093/nsr/nwac148
Autor:
Sin Man Lam, Jie Li, Huan Sun, Weining Mao, Zongmin Lu, Qingshuo Zhao, Chao Han, Xia Gong, Binhua Jiang, Gek Huey Chua, Zhenwen Zhao, Fanwei Meng, Guanghou Shui
Publikováno v:
Molecular biology and evolution. 39(4)
Sinocyclocheilus represents a rare, freshwater teleost genus endemic to China that comprises the river-dwelling surface fish and the cave-dwelling cavefish. Using a combinatorial approach of quantitative lipidomics and mass-spectrometry imaging (MSI)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d9b6ca1b1a9c4e82577c77356f72a8
https://pubmed.ncbi.nlm.nih.gov/35277964
https://pubmed.ncbi.nlm.nih.gov/35277964
Publikováno v:
Science Bulletin. 65:1840-1848
Acyl-coenzyme A thioesters (acyl-CoAs) denote a key class of intermediary metabolites that lies at the hub of major metabolic pathways. The great diversity in polarity between short- and long-chain acyl-CoAs makes it technically challenging to cover
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ded6d1cb5f0b5d17b2456709082f2b6c
https://doi.org/10.1016/j.scib.2020.07.023
https://doi.org/10.1016/j.scib.2020.07.023
Autor:
Raoxu Wang, He Tian, Chao Zhang, Tao Yang, Guanghou Shui, Gek Huey Chua, Jin-Wen Song, Fan Ping Meng, Shaohua Zhang, Lei Huang, Wen-Jing Cao, Ji Yuan Zhang, Zhe Xu, Si Yu Wang, Peng Xia, Ming Shi, Bowen Li, Jun Liang Fu, Sin Man Lam, Fu-Sheng Wang, Zehua Wang, Tian Jun Jiang, Xing Fan
Publikováno v:
Cell Metabolism
Summary The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented threat to global public health. Herein, we utilized a combination of targeted and untargeted tandem mass spectrometry to analyze the plasma lipidome and metabolome in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d778b5b622a25cba9dd90df662625374
https://pubmed.ncbi.nlm.nih.gov/32610096
https://pubmed.ncbi.nlm.nih.gov/32610096
Publikováno v:
Oncotarget
// Sin Man Lam 1 , Gek Huey Chua 1 , Xiao-Jiang Li 1 , Bing Su 2 and Guanghou Shui 1 1 State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 2 State Key L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd2115f7905cac3c9274975363e26db
https://doi.org/10.18632/oncotarget.11190
https://doi.org/10.18632/oncotarget.11190
Autor:
Deepak Sarda1 deepak@bii.a-star.edu.sg, Gek Huey Chua1 chuagh@bii.a-star.edu.sg, Kuo-Bin Li1 kuobin@bii.a-star.edu.sg, Krishnan, Arun1 arun@bii.a-star.edu.sg
Publikováno v:
BMC Bioinformatics. 2005, Vol. 6, p152-12. 12p. 5 Charts, 4 Graphs.
Autor:
Laura E. Via, Martin W. Bratschi, Soohee Hwang, Hui Ming Lim, Gerd Michel, Mamadou Daffé, Gek Huey Chua, Clifton E. Barry, Hyun-Kyung Kwak, Véronique Dartois, Anne K. Bendt, Marie-Antoinette Lanéelle, Guanghou Shui, Markus R. Wenk, Seokyong Eum, Ignasius A. Jappar, Ang Lay Teng Michelle, Maxime Herve, Jong-Soek Lee, Siti Zarina Zainul Rahim
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine; Vol 4
EMBO Molecular Medicine; Vol 4
Mycolic acids are attractive diagnostic markers for tuberculosis (TB) infection because they are bacteria-derived, contain information about bacterial species, modulate host–pathogen interactions and are chemically inert. Here, we present a novel a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b24bae5e802c2d1ffa759290c2e503c
Publikováno v:
Cell Cycle. 6:2219-2226
Cyclin dependent kinases (CDK) associate with cyclins to regulate cell cycle progression and gene transcription by phosphorylating key proteins. The different cyclin-CDK complexes display differences in substrate specificities with substrates binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4111f31fb4fbcfc4fbf0b0131a22b50d
https://doi.org/10.4161/cc.6.18.4706
https://doi.org/10.4161/cc.6.18.4706
Publikováno v:
Journal of Bioinformatics and Computational Biology. :1245-1267
Physicochemcial properties of amino acids are important factors in determining protein structure and function. Most approaches make use of averaged properties over entire domains or even proteins to analyze their structure or function. This level of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82294d2de9aa14ff07b81c11c2e3220
https://doi.org/10.1142/s0219720006002442
https://doi.org/10.1142/s0219720006002442