Telomere tracking from birth to adulthood and residential traffic exposure

Autor: Esmée M. Bijnens, Maurice P. Zeegers, Catherine Derom, Dries S. Martens, Marij Gielen, Geja J. Hageman, Michelle Plusquin, Evert Thiery, Robert Vlietinck, Tim S. Nawrot

Publikováno v: BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)

Abstract Background Telomere attrition is extremely rapid during the first years of life, while lifestyle during adulthood exerts a minor impact. This suggests that early life is an important period in the determination of telomere length. We investi

Externí odkaz: https://doaj.org/article/e9c51fdcd2d441aa84e3bc2db15e8df9

Cross-Sectional Associations between Dietary Daily Nicotinamide Intake and Patient-Reported Outcomes in Colorectal Cancer Survivors, 2 to 10 Years Post-Diagnosis

Autor: Geja J. Hageman, Annaleen Koole, Marlou-Floor Kenkhuis, Simone J. P. M. Eussen, Wenbo Wu, Frederik-Jan van Schooten, Matty P. Weijenberg, Stephanie O. Breukink, Martijn J.L. Bours

Publikováno v: Nutrients, 13(11):3707. Multidisciplinary Digital Publishing Institute (MDPI)
Nutrients
Nutrients, Vol 13, Iss 3707, p 3707 (2021)
Volume 13
Issue 11

Supplementation with nicotinamide adenine dinucleotide (NAD+) precursors including dietary nicotinamide has been found to boost tissue NAD+ levels and ameliorate oxidative stress-induced damage that contributes to aging and aging-related diseases. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654bf2e375e16cf11102abf5a63fa23c
https://cris.maastrichtuniversity.nl/en/publications/31583bad-b1ff-493e-8a3d-3276bea92000

The vitamin B6 paradox

Autor: Guido R.M.M. Haenen, Antoon Opperhuizen, Aalt Bast, Geja J. Hageman, Eugène H.J.M. Jansen, Misha F. Vrolijk

Publikováno v: Toxicology in Vitro, 44, 206-212. Elsevier Science

Vitamin B6 is a water-soluble vitamin that functions as a coenzyme in many reactions involved in amino acid, carbohydrates and lipid metabolism. Since 2014, > 50 cases of sensory neuronal pain due to vitamin B6 supplementation were reported. Up to no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c2a7188693583eb7b69760a3d9e9c7
https://doi.org/10.1016/j.tiv.2017.07.009

Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD

Autor: Geja J. Hageman, Frits M.E. Franssen, Niki L. Reynaert, Emiel F.M. Wouters, Poornima Gopal, Martijn A. Spruit, Lowie E.G.W. Vanfleteren, Erica P.A. Rutten

Publikováno v: Chest, 149(1), 53-61. Elsevier

BACKGROUND: Accelerated aging has been proposed as a pathologic mechanism of various chronic diseases, including COPD. This concept has almost exclusively been approached by analyses of individual markers. We investigated whether COPD is associated w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f408ad70e9c774c8bb48152d85922dce
https://doi.org/10.1378/chest.15-0645

Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies

Autor: Gil Atzmon, Rosalind Ramsey-Goldman, Barry J. McDonnell, Yun-Ling Zheng, David Gilley, Teresa E. Seeman, Maciej Tomaszewski, Massimo Mangino, Geja J. Hageman, Florian Kronenberg, Iiris Hovatta, Giuseppe Paolisso, Line Rode, Ellen W. Demerath, Jaakko Kaprio, Katarina Nordfjäll, Jonathan N. Hofmann, Peter Willeit, Rosana Maria dos Reis, Barbara Kollerits, Andrea Elena Iglesias Molli, Guo Cheng, Wei Zheng, Karen A. Mather, Daniel Eisenberg, Fadi J. Charchar, Sarah E. Harris, Bianca D’Antono, Jason Y.Y. Wong, Sofia Pavanello, Lisa A. Boardman, Guillaume Paré, Jacob B. H. Hjelmborg, Erik J. Giltay, Tim De Meyer, Evangelia Antoniou, Dmytro Krasnienkov, Maurice P. Zeegers, Marek Kasielski, Audrey E. Hendricks, Linda Broer, Lifang Hou, Andrew Steptoe, Andrew J. Pellatt, Jennifer A. Nettleton, Vanessa A. Diaz, Steven C. Hunt, Marij Gielen, Josine E. Verhoeven, Christian Gieger, Roxanne Schaakxs, Belinda L. Needham, Catherine Duggan, Timo E. Strandberg, Ute Mons, Klelia D. Salpea, Jeremy D. Kark, Raffaela Zannolli, Muthuswamy Balasubramanyam, Michael Chong, Richard P. Ebstein, Daniel Bunout, Amelia Marti, Kristina Sundquist, Lisa Mirabello, Hisham Nassar, David J. Kurz, Ramin Farzaneh-Far, Ilja Demuth, Pim van der Harst

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Christensen, K & TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length : A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475
Gielen, M, Hageman, G J, Antoniou, E E, Nordfjall, K, Mangino, M, Balasubramanyam, M, De Meyer, T, Hendricks, A E, Giltay, E J, Hunt, S C, Nettleton, J A, Salpea, K D, Diaz, V A, Farzaneh-far, R, Atzmon, G, Harris, S E, Hou, L, Gilley, D, Hovatta, I, Kark, J D, Nassar, H, Kurz, D J, Mather, K A, Willeit, P, Zheng, Y, Pavanello, S, Demerath, E W, Rode, L, Bunout, D, Steptoe, A, Boardman, L, Marti, A, Needham, B, Zheng, W, Ramsey-goldman, R, Pellatt, A J, Kaprio, J, Hofmann, J N, Gieger, C, Paolisso, G, Hjelmborg, J B H, Mirabello, L, Seeman, T, Wong, J, Van Der Harst, P, Broer, L, Kronenberg, F, Kollerits, B, Strandberg, T, Eisenberg, D T A, Duggan, C, Verhoeven, J E, Schaakxs, R, Zannolli, R, Dos Reis, R M R, Charchar, F J, Tomaszewski, M, Mons, U, Demuth, I, Molli, A E I, Cheng, G, Krasnienkov, D, D'antono, B, Kasielski, M, Mcdonnell, B J, Ebstein, R P, Sundquist, K, Pare, G, Chong, M & Zeegers, M P 2018, ' Body mass index is negatively associated with telomere length: a collaborative cross-sectional meta-analysis of 87 observational studies ', The American journal of clinical nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
TELOMAAS group 2018, ' Body mass index is negatively associated with telomere length: A collaborative cross-sectional meta-analysis of 87 observational studies ', American Journal of Clinical Nutrition, vol. 108, no. 3, pp. 453-475 . https://doi.org/10.1093/ajcn/nqy107
American Journal of Clinical Nutrition, 108(3), 453-475. Oxford University Press
American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, 108(3), 453-475. American Society for Nutrition

Background: Even before the onset of age-related diseases, obesity might be a contributing factor to the cumulative burden of oxidative stress and chronic inflammation throughout the life course. Obesity may therefore contribute to accelerated shorte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fdf732c38593d0bc118ec9a93d2b12d
https://hdl.handle.net/1887/96085