High throughput drug screening identifies resveratrol as suppressor of hepatic SELENOP expression.

Autor: Hackler J; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Demircan K; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Chillon TS; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Sun Q; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Geisler N; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Schupp M; Institute of Pharmacology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany., Renko K; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany; German Federal Institute for Risk Assessment, Department Experimental Toxicology and ZEBET, 12277, Berlin, Germany., Schomburg L; Institute for Experimental Endocrinology, Charité-Universitätsmedizin Berlin, Max Rubner Center (MRC) for Cardiovascular Metabolic Renal Research, 10115, Berlin, Germany. Electronic address: lutz.schomburg@charite.de.

Publikováno v: Redox biology [Redox Biol] 2023 Feb; Vol. 59, pp. 102592. Date of Electronic Publication: 2022 Dec 26.

Acute resistance exercise and training reduce desmin phosphorylation at serine 31 in human skeletal muscle, making the protein less prone to cleavage.

Autor: Jacko, Daniel¹ (AUTHOR) d.jacko@dshs-koeln.de, Schaaf, Kirill¹ (AUTHOR), Aussieker, Thorben² (AUTHOR), Masur, Lukas¹ (AUTHOR), Zacher, Jonas³ (AUTHOR), Bersiner, Käthe⁴ (AUTHOR), Bloch, Wilhelm¹ (AUTHOR), Gehlert, Sebastian⁴ (AUTHOR)

Publikováno v: Scientific Reports. 11/14/2024, Vol. 12 Issue 1, p1-15. 15p.

Doxycycline decelerates aging in progeria mice.

Autor: Wang, Ming¹ (AUTHOR) kuailewm@126.com, Zhang, Jie¹ (AUTHOR), Qiu, Jiangping¹ (AUTHOR), Ma, Xuan¹ (AUTHOR), Xu, Chenzhong¹ (AUTHOR), Wu, Qiuhuan¹ (AUTHOR), Xing, Shaojun² (AUTHOR), Chen, Xinchun² (AUTHOR), Liu, Baohua¹ (AUTHOR) ppliew@szu.edu.cn

Publikováno v: Aging Cell. Jul2024, Vol. 23 Issue 7, p1-6. 6p.

Detection of functional protein domains by unbiased genome-wide forward genetic screening.

Autor: Herzog M; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK., Puddu F; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK., Coates J; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK., Geisler N; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK., Forment JV; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK. j.forment@gurdon.cam.ac.uk.; AstraZeneca, Oncology DNA damage response group, Hodgkin Building, 310 Cambridge Science Park, Milton Road, CB4 0WG, Cambridge, UK. j.forment@gurdon.cam.ac.uk., Jackson SP; The Wellcome/CRUK Gurdon Institute and Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QN, Cambridge, UK. s.jackson@gurdon.cam.ac.uk.

Publikováno v: Scientific reports [Sci Rep] 2018 Apr 18; Vol. 8 (1), pp. 6161. Date of Electronic Publication: 2018 Apr 18.

DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome‐Lysosome Fusion.

Autor: Ding, Xulong^1,2 (AUTHOR), Cao, Shuqiang³ (AUTHOR), Wang, Qing¹ (AUTHOR), Du, Bin¹ (AUTHOR), Lu, Kefeng¹ (AUTHOR), Qi, Shiqian¹ (AUTHOR), Cheng, Ying¹ (AUTHOR), Tuo, Qing‐zhang¹ (AUTHOR), Liang, Weibo³ (AUTHOR) liangweibo@scu.edu.cn, Lei, Peng¹ (AUTHOR) peng.lei@scu.edu.cn

Publikováno v: Advanced Science. 4/17/2024, Vol. 11 Issue 15, p1-14. 14p.